Unraveling the crystal structure of Leptospira kmetyi riboflavin synthase and computational analyses for potential development of new antibacterials
Over the last decade, an escalating number of reported cases of leptospirosis in Malaysia has resulted in a significant number of deaths. Leptospirosis is caused by Leptospira sp., which is disseminated by soil and water. Due to the absolute dependence of microbes on this biosynthesis pathway couple...
| Main Authors: | Mohamad Aris, Sayangku Nor Ariati, Raja Abd Rahman, Raja Noor Zaliha, Mohamad Ali, Mohd Shukuri, Jonet, Mohd Anuar, Taiki, Motomura, Muhd Noor, Noor Dina, Mohd Shariff, Fairolniza, Kai-Cheng, Hsu, Thean, Chor Leow |
|---|---|
| Format: | Article |
| Published: |
Elsevier BV
2022
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/102542/ |
Similar Items
Unravelling the structure of riboflavin synthase from Leptospira kmetyi for designing potential anti-bacterial drug
by: Mohamad Aris, Sayangku Nor Ariati
Published: (2021)
by: Mohamad Aris, Sayangku Nor Ariati
Published: (2021)
Identification of potential riboflavin synthase inhibitors by virtual screening and molecular dynamics simulation studies
by: Mohamad Aris, Sayangku Nor Ariati, et al.
Published: (2021)
by: Mohamad Aris, Sayangku Nor Ariati, et al.
Published: (2021)
Detection of Leptospira kmetyi at recreational areas in Peninsular Malaysia
by: Mohamad Zaki, Aznida, et al.
Published: (2020)
by: Mohamad Zaki, Aznida, et al.
Published: (2020)
Leptospira kmetyi sp. nov., isolated from an environmental source in Malaysia.
by: Slack, Andrew T., et al.
Published: (2009)
by: Slack, Andrew T., et al.
Published: (2009)
Cloning, expressing, and purification of riboflavin synthase from photobacterium sp. j15
by: Dorrazehi, Gol Mohammad
Published: (2014)
by: Dorrazehi, Gol Mohammad
Published: (2014)
In silico identification and characterization of potential druggable targets among hypothetical proteins of Leptospira interrogans serovar Copenhageni: a comprehensive bioinformatics approach
by: Siddiqui, Quratulain, et al.
Published: (2022)
by: Siddiqui, Quratulain, et al.
Published: (2022)
Crystallographic analysis of ground and space thermostable T1 lipase crystal obtained via counter diffusion method approach
by: Mohamad Aris, Sayangku Nor Ariati, et al.
Published: (2014)
by: Mohamad Aris, Sayangku Nor Ariati, et al.
Published: (2014)
Development of indirect IgG ELISA for detection of leptospiral infection in cattle using Malaysian local isolate Leptospira kmetyi serovar malaysia strain Bejo-Iso9
by: Abdul Rahman, Mohammad Sabri, et al.
Published: (2017)
by: Abdul Rahman, Mohammad Sabri, et al.
Published: (2017)
Expression and characterization of thermotolerant lipase with broad pH profiles isolated from an Antarctic Pseudomonas sp strain AMS3
by: Latip, Wahhida, et al.
Published: (2016)
by: Latip, Wahhida, et al.
Published: (2016)
Leptospira interrogans and Leptospira kirschneri are the dominant Leptospira species causing human leptospirosis in Central Malaysia
by: Philip, Noraini, et al.
Published: (2020)
by: Philip, Noraini, et al.
Published: (2020)
Crystallographic analysis of ground- and space-grown thermostable T1 lipase crystal
by: Mohamad Aris, Sayangku Nor Ariati
Published: (2013)
by: Mohamad Aris, Sayangku Nor Ariati
Published: (2013)
Leptospira dzianensis and Leptospira putramalaysiae are later heterotypic synonyms of Leptospira yasudae and Leptospira stimsonii
by: Casanovas-Massana, Arnau, et al.
Published: (2021)
by: Casanovas-Massana, Arnau, et al.
Published: (2021)
Adaptational properties and applications of cold-active lipase from psychrophilic bacteria
by: Maiangwa, Jonathan, et al.
Published: (2015)
by: Maiangwa, Jonathan, et al.
Published: (2015)
Crystallization and structure elucidation of GDSL esterase of Photobacterium sp. J15
by: Syed Mazlan, Sharifah Nur Hidayah, et al.
Published: (2018)
by: Syed Mazlan, Sharifah Nur Hidayah, et al.
Published: (2018)
Molecular dynamic simulation of space and earth-grown crystal structures of thermostable T1 lipase geobacillus zalihae revealed a better structure
by: Ishak, Siti Nor Hasmah, et al.
Published: (2017)
by: Ishak, Siti Nor Hasmah, et al.
Published: (2017)
Molecular dynamic simulation of space and earth-grown crystal structures of thermostable T1 lipase Geobacillus zalihae revealed a better structure
by: Ishak, Siti Nor Hasmah, et al.
Published: (2017)
by: Ishak, Siti Nor Hasmah, et al.
Published: (2017)
Crystallization and preliminary X-ray crystallographic analysis of highly thermostable L2 lipase from the newly isolated Bacillus sp. L2
by: Mohd Shariff, Fairolniza, et al.
Published: (2010)
by: Mohd Shariff, Fairolniza, et al.
Published: (2010)
Riboflavin Adsorption On Mesoporous Carbon By Using Aspen Adsorption Simulation
by: Suhaimi, Muhammad Alif
Published: (2021)
by: Suhaimi, Muhammad Alif
Published: (2021)
Altering the regioselectivity of T1 lipase from Geobacillus zalihae toward sn-3 acylglycerol using a rational design approach
by: Albayati, Samah Hashim, et al.
Published: (2023)
by: Albayati, Samah Hashim, et al.
Published: (2023)
Main structural targets for engineering lipase substrate specificity
by: Albayati, Samah Hashim, et al.
Published: (2020)
by: Albayati, Samah Hashim, et al.
Published: (2020)
Single residue substitution at N-terminal affects temperature stability and activity of L2 lipase
by: Bukhari, Noramirah, et al.
Published: (2020)
by: Bukhari, Noramirah, et al.
Published: (2020)
The effect of N-terminal domain removal towards the biochemical and structural features of a thermotolerant lipase from an Antarctic Pseudomonas sp. strain AMS3
by: Latip, Wahhida, et al.
Published: (2018)
by: Latip, Wahhida, et al.
Published: (2018)
Enzymatic properties and mutational studies of chalcone synthase from Physcomitrella patens
by: Raja Abdul Rahman, Raja Noor Zaliha, et al.
Published: (2012)
by: Raja Abdul Rahman, Raja Noor Zaliha, et al.
Published: (2012)
Expression, characterisation and homology modelling of a novel hormone-sensitive lipase (HSL)-like esterase from Glaciozyma antarctica
by: Mohamad Tahir, Hiryahafira, et al.
Published: (2020)
by: Mohamad Tahir, Hiryahafira, et al.
Published: (2020)
Rosmarinic acid as pancreatic lipase inhibitor
by: Raja Abd. Rahman, Raja Noor Zaliha, et al.
Published: (2016)
by: Raja Abd. Rahman, Raja Noor Zaliha, et al.
Published: (2016)
Determination of riboflavin in commercial drinks using fluorescence spectroscopy / Anida Yusof
by: Yusof, Anida
Published: (2009)
by: Yusof, Anida
Published: (2009)
Optimization of non-effervescent riboflavin gastroretentive floating tablets using mixture design
by: Arobi Katha, Umme Tabassum, et al.
Published: (2024)
by: Arobi Katha, Umme Tabassum, et al.
Published: (2024)
Unravelling
by: Farren, Anne
Published: (2014)
by: Farren, Anne
Published: (2014)
Lid opening and conformational stability of T1 lipase is mediated by increasing chain length polar solvents
by: Maiangwa, Jonathan, et al.
Published: (2017)
by: Maiangwa, Jonathan, et al.
Published: (2017)
Ancestral sequence reconstruction of ancient lipase from family I.3 bacterial lipolytic enzymes
by: Mohd Rozi, Mohamad Farihan Afnan, et al.
Published: (2022)
by: Mohd Rozi, Mohamad Farihan Afnan, et al.
Published: (2022)
Bacteriocin release protein mediated secretory expression of recombinant chalcone synthase in Escherichia coli
by: Zakaria, Iffah Izzati, et al.
Published: (2011)
by: Zakaria, Iffah Izzati, et al.
Published: (2011)
Structure elucidation and docking analysis of 5M mutant of T1 lipase Geobacillus zalihae
by: Ishak, Siti Nor Hasmah, et al.
Published: (2021)
by: Ishak, Siti Nor Hasmah, et al.
Published: (2021)
Enhancing the stability of Geobacillus zalihae T1 lipase in organic solvents and insights into the structural stability of its variants
by: Maiangwa, Jonathan, et al.
Published: (2021)
by: Maiangwa, Jonathan, et al.
Published: (2021)
Insects induced mango fruit rot: unraveling the culprits
by: Subramaniam, Sivagami, et al.
Published: (2024)
by: Subramaniam, Sivagami, et al.
Published: (2024)
Effects of alcohol concentration and temperature on the dynamics and stability of mutant Staphylococcal lipase
by: Ong, Shir Nee, et al.
Published: (2023)
by: Ong, Shir Nee, et al.
Published: (2023)
Newly isolated alkane hydroxylase and lipase producing Geobacillus and Anoxybacillus species involved in crude oil degradation
by: Yusoff, Durratul Fatini, et al.
Published: (2020)
by: Yusoff, Durratul Fatini, et al.
Published: (2020)
Effect of cysteine mutation at ca2+ coordinating residues to the autolysis, folding and hydrophobicity of full length and mature rand protease: molecular dynamics simulation and essential dynamics
by: Mohd Azrin, Nur Aliyah, et al.
Published: (2023)
by: Mohd Azrin, Nur Aliyah, et al.
Published: (2023)
CsoR metalloregulatory protein: function, mechanism and relevance
by: Mangavelu, Ashwaani, et al.
Published: (2017)
by: Mangavelu, Ashwaani, et al.
Published: (2017)
Crystallization and structure elucidation of thermostable lipases
by: Mohd Shariff, Fairolniza, et al.
Published: (2013)
by: Mohd Shariff, Fairolniza, et al.
Published: (2013)
Inhibition of microbial pathogens by riboflavin, ultraviolet A and selected antibiotic combinations / Aarthi Ahgilan
by: Aarthi, Ahgilan
Published: (2017)
by: Aarthi, Ahgilan
Published: (2017)
Similar Items
-
Unravelling the structure of riboflavin synthase from Leptospira kmetyi for designing potential anti-bacterial drug
by: Mohamad Aris, Sayangku Nor Ariati
Published: (2021) -
Identification of potential riboflavin synthase inhibitors by virtual screening and molecular dynamics simulation studies
by: Mohamad Aris, Sayangku Nor Ariati, et al.
Published: (2021) -
Detection of Leptospira kmetyi at recreational areas in Peninsular Malaysia
by: Mohamad Zaki, Aznida, et al.
Published: (2020) -
Leptospira kmetyi sp. nov., isolated from an environmental source in Malaysia.
by: Slack, Andrew T., et al.
Published: (2009) -
Cloning, expressing, and purification of riboflavin synthase from photobacterium sp. j15
by: Dorrazehi, Gol Mohammad
Published: (2014)