MYBIOTA: a birth cohort on maternal and infant microbiota and its impact on infant health in Malaysia
Background: The microbiota plays a key role in early immunity maturation that affects infant health and is associated with the development of non-communicable diseases and allergies in later life. Objective: The MYBIOTA is a prospective mother-infant cohort study in Malaysia aiming to determine the...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
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Frontiers Research Foundation
2022
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| Online Access: | http://psasir.upm.edu.my/id/eprint/102270/ |
| _version_ | 1848863758846263296 |
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| author | Eow, Shiang Yen Gan, Wan Ying Jiang, Tiemin Loh, Su Peng Lee, Ling Jun Chin, Yit Siew Thian, Leslie Lung Than How, Kang Nien Thong, Pui Ling Liu, Yanpin Zhao, Junying Chen, Lijun |
| author_facet | Eow, Shiang Yen Gan, Wan Ying Jiang, Tiemin Loh, Su Peng Lee, Ling Jun Chin, Yit Siew Thian, Leslie Lung Than How, Kang Nien Thong, Pui Ling Liu, Yanpin Zhao, Junying Chen, Lijun |
| author_sort | Eow, Shiang Yen |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Background: The microbiota plays a key role in early immunity maturation that affects infant health and is associated with the development of non-communicable diseases and allergies in later life. Objective: The MYBIOTA is a prospective mother-infant cohort study in Malaysia aiming to determine the association between gut microbiota with infant health (temperament, gastrointestinal disorders, eczema, asthma, and developmental delays) in Selangor, Malaysia. Methods: Pregnant mothers will be enrolled in their first trimester of pregnancy, and follow-ups will be done for infants during their first year of life. Maternal-infant biological samples (blood, feces, saliva, urine, and breast milk), anthropometric, dietary, and clinical information will be collected at different time points from early pregnancy to 12 months postpartum. Discussion: This study could provide a better understanding of the colonization and development of the gut microbiome during early life and its impact on infant health. Clinical trial registration: https://clinicaltrials.gov/, identifier NCT04919265. |
| first_indexed | 2025-11-15T13:38:01Z |
| format | Article |
| id | upm-102270 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T13:38:01Z |
| publishDate | 2022 |
| publisher | Frontiers Research Foundation |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1022702023-06-17T22:53:12Z http://psasir.upm.edu.my/id/eprint/102270/ MYBIOTA: a birth cohort on maternal and infant microbiota and its impact on infant health in Malaysia Eow, Shiang Yen Gan, Wan Ying Jiang, Tiemin Loh, Su Peng Lee, Ling Jun Chin, Yit Siew Thian, Leslie Lung Than How, Kang Nien Thong, Pui Ling Liu, Yanpin Zhao, Junying Chen, Lijun Background: The microbiota plays a key role in early immunity maturation that affects infant health and is associated with the development of non-communicable diseases and allergies in later life. Objective: The MYBIOTA is a prospective mother-infant cohort study in Malaysia aiming to determine the association between gut microbiota with infant health (temperament, gastrointestinal disorders, eczema, asthma, and developmental delays) in Selangor, Malaysia. Methods: Pregnant mothers will be enrolled in their first trimester of pregnancy, and follow-ups will be done for infants during their first year of life. Maternal-infant biological samples (blood, feces, saliva, urine, and breast milk), anthropometric, dietary, and clinical information will be collected at different time points from early pregnancy to 12 months postpartum. Discussion: This study could provide a better understanding of the colonization and development of the gut microbiome during early life and its impact on infant health. Clinical trial registration: https://clinicaltrials.gov/, identifier NCT04919265. Frontiers Research Foundation 2022-09-27 Article PeerReviewed Eow, Shiang Yen and Gan, Wan Ying and Jiang, Tiemin and Loh, Su Peng and Lee, Ling Jun and Chin, Yit Siew and Thian, Leslie Lung Than and How, Kang Nien and Thong, Pui Ling and Liu, Yanpin and Zhao, Junying and Chen, Lijun (2022) MYBIOTA: a birth cohort on maternal and infant microbiota and its impact on infant health in Malaysia. Frontiers in Nutrition, 9. art. no. 994607. 1- 11. ISSN 2296-861X https://www.frontiersin.org/articles/10.3389/fnut.2022.994607/full 10.3389/fnut.2022.994607 |
| spellingShingle | Eow, Shiang Yen Gan, Wan Ying Jiang, Tiemin Loh, Su Peng Lee, Ling Jun Chin, Yit Siew Thian, Leslie Lung Than How, Kang Nien Thong, Pui Ling Liu, Yanpin Zhao, Junying Chen, Lijun MYBIOTA: a birth cohort on maternal and infant microbiota and its impact on infant health in Malaysia |
| title | MYBIOTA: a birth cohort on maternal and infant microbiota and its impact on infant health in Malaysia |
| title_full | MYBIOTA: a birth cohort on maternal and infant microbiota and its impact on infant health in Malaysia |
| title_fullStr | MYBIOTA: a birth cohort on maternal and infant microbiota and its impact on infant health in Malaysia |
| title_full_unstemmed | MYBIOTA: a birth cohort on maternal and infant microbiota and its impact on infant health in Malaysia |
| title_short | MYBIOTA: a birth cohort on maternal and infant microbiota and its impact on infant health in Malaysia |
| title_sort | mybiota: a birth cohort on maternal and infant microbiota and its impact on infant health in malaysia |
| url | http://psasir.upm.edu.my/id/eprint/102270/ http://psasir.upm.edu.my/id/eprint/102270/ http://psasir.upm.edu.my/id/eprint/102270/ |