Mechanical and imaging properties of a clinical-grade kidney phantom based on polydimethylsiloxane and elastomer
Medical imaging phantoms are considered critical in mimicking the properties of human tissue for calibration, training, surgical planning, and simulation purposes. Hence, the stability and accuracy of the imaging phantom play a significant role in diagnostic imaging. This study aimed to evaluate the...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
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Multidisciplinary Digital Publishing Institute
2022
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| Online Access: | http://psasir.upm.edu.my/id/eprint/102153/ |
| _version_ | 1848863729108647936 |
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| author | Kamal, Izdihar Abdul Razak, Hairil Rashmizal Abdul Karim, Muhammad Khalis Mashohor, Syamsiah Ying, Josephine Chyi Liew Low, Yiin Jian Zaaba, Nur Atiqah Mazlan, Norkhairunnisa Mohd Rafi, Nur Athirah Syima |
| author_facet | Kamal, Izdihar Abdul Razak, Hairil Rashmizal Abdul Karim, Muhammad Khalis Mashohor, Syamsiah Ying, Josephine Chyi Liew Low, Yiin Jian Zaaba, Nur Atiqah Mazlan, Norkhairunnisa Mohd Rafi, Nur Athirah Syima |
| author_sort | Kamal, Izdihar |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Medical imaging phantoms are considered critical in mimicking the properties of human tissue for calibration, training, surgical planning, and simulation purposes. Hence, the stability and accuracy of the imaging phantom play a significant role in diagnostic imaging. This study aimed to evaluate the influence of hydrogen silicone (HS) and water (H2O) on the compression strength, radiation attenuation properties, and computed tomography (CT) number of the blended Polydimethylsiloxane (PDMS) samples, and to verify the best material to simulate kidney tissue. Four samples with different compositions were studied, including samples S1, S2, S3, and S4, which consisted of PDMS 100%, HS/PDMS 20:80, H2O/PDMS 20:80, and HS/H2O/PDMS 20:40:40, respectively. The stability of the samples was assessed using compression testing, and the attenuation properties of sample S2 were evaluated. The effective atomic number of S2 showed a similar pattern to the human kidney tissue at 1.50 × 10−1 to 1 MeV. With the use of a 120 kVp X-ray beam, the CT number quantified for S2, as well measured 40 HU, and had the highest contrast-to-noise ratio (CNR) value. Therefore, the S2 sample formulation exhibited the potential to mimic the human kidney, as it has a similar dynamic and is higher in terms of stability as a medical phantom. |
| first_indexed | 2025-11-15T13:37:32Z |
| format | Article |
| id | upm-102153 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T13:37:32Z |
| publishDate | 2022 |
| publisher | Multidisciplinary Digital Publishing Institute |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1021532023-06-15T22:06:50Z http://psasir.upm.edu.my/id/eprint/102153/ Mechanical and imaging properties of a clinical-grade kidney phantom based on polydimethylsiloxane and elastomer Kamal, Izdihar Abdul Razak, Hairil Rashmizal Abdul Karim, Muhammad Khalis Mashohor, Syamsiah Ying, Josephine Chyi Liew Low, Yiin Jian Zaaba, Nur Atiqah Mazlan, Norkhairunnisa Mohd Rafi, Nur Athirah Syima Medical imaging phantoms are considered critical in mimicking the properties of human tissue for calibration, training, surgical planning, and simulation purposes. Hence, the stability and accuracy of the imaging phantom play a significant role in diagnostic imaging. This study aimed to evaluate the influence of hydrogen silicone (HS) and water (H2O) on the compression strength, radiation attenuation properties, and computed tomography (CT) number of the blended Polydimethylsiloxane (PDMS) samples, and to verify the best material to simulate kidney tissue. Four samples with different compositions were studied, including samples S1, S2, S3, and S4, which consisted of PDMS 100%, HS/PDMS 20:80, H2O/PDMS 20:80, and HS/H2O/PDMS 20:40:40, respectively. The stability of the samples was assessed using compression testing, and the attenuation properties of sample S2 were evaluated. The effective atomic number of S2 showed a similar pattern to the human kidney tissue at 1.50 × 10−1 to 1 MeV. With the use of a 120 kVp X-ray beam, the CT number quantified for S2, as well measured 40 HU, and had the highest contrast-to-noise ratio (CNR) value. Therefore, the S2 sample formulation exhibited the potential to mimic the human kidney, as it has a similar dynamic and is higher in terms of stability as a medical phantom. Multidisciplinary Digital Publishing Institute 2022-01-28 Article PeerReviewed Kamal, Izdihar and Abdul Razak, Hairil Rashmizal and Abdul Karim, Muhammad Khalis and Mashohor, Syamsiah and Ying, Josephine Chyi Liew and Low, Yiin Jian and Zaaba, Nur Atiqah and Mazlan, Norkhairunnisa and Mohd Rafi, Nur Athirah Syima (2022) Mechanical and imaging properties of a clinical-grade kidney phantom based on polydimethylsiloxane and elastomer. Polymers, 14 (3). art. no. 535. pp. 1-10. ISSN 2073-4360 https://www.mdpi.com/2073-4360/14/3/535 10.3390/polym14030535 |
| spellingShingle | Kamal, Izdihar Abdul Razak, Hairil Rashmizal Abdul Karim, Muhammad Khalis Mashohor, Syamsiah Ying, Josephine Chyi Liew Low, Yiin Jian Zaaba, Nur Atiqah Mazlan, Norkhairunnisa Mohd Rafi, Nur Athirah Syima Mechanical and imaging properties of a clinical-grade kidney phantom based on polydimethylsiloxane and elastomer |
| title | Mechanical and imaging properties of a clinical-grade kidney phantom based on polydimethylsiloxane and elastomer |
| title_full | Mechanical and imaging properties of a clinical-grade kidney phantom based on polydimethylsiloxane and elastomer |
| title_fullStr | Mechanical and imaging properties of a clinical-grade kidney phantom based on polydimethylsiloxane and elastomer |
| title_full_unstemmed | Mechanical and imaging properties of a clinical-grade kidney phantom based on polydimethylsiloxane and elastomer |
| title_short | Mechanical and imaging properties of a clinical-grade kidney phantom based on polydimethylsiloxane and elastomer |
| title_sort | mechanical and imaging properties of a clinical-grade kidney phantom based on polydimethylsiloxane and elastomer |
| url | http://psasir.upm.edu.my/id/eprint/102153/ http://psasir.upm.edu.my/id/eprint/102153/ http://psasir.upm.edu.my/id/eprint/102153/ |