Mantle Cell Lymphoma Masquerading as obstructive sleep apnoea

Tonsillar malignancy typically presents with asymmetrical tonsillar enlargement, lesion on the tonsils, sore throat or a neck mass. We report a case of unsuspected tonsillar malignancy in a 56-year-old gentleman who presented with symptoms of obstructive sleep apnoea. His tonsils were grade III bila...

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Main Authors: Ishak, Noor Liza, Teng, Tan Sui, Mahat, Mahfida
Format: Article
Language:English
Published: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2022
Online Access:http://psasir.upm.edu.my/id/eprint/102133/
http://psasir.upm.edu.my/id/eprint/102133/1/2023051612005750_MJMHS_0431.pdf
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author Ishak, Noor Liza
Teng, Tan Sui
Mahat, Mahfida
author_facet Ishak, Noor Liza
Teng, Tan Sui
Mahat, Mahfida
author_sort Ishak, Noor Liza
building UPM Institutional Repository
collection Online Access
description Tonsillar malignancy typically presents with asymmetrical tonsillar enlargement, lesion on the tonsils, sore throat or a neck mass. We report a case of unsuspected tonsillar malignancy in a 56-year-old gentleman who presented with symptoms of obstructive sleep apnoea. His tonsils were grade III bilaterally with normal mucosa. Tonsillectomy was performed to improve patient’s compliance with Continuous Positive Airway Pressure (CPAP) therapy. These tonsillar specimens were reported to be Mantle Cell Lymphoma (MCL) based on the histology and ancillary studies. This case highlights that benign-looking symmetrical tonsillar enlargement can harbour occult malignancy. It is important to note that OSA symptoms may be the presentation for haematological malignancies. Tonsillar specimens should be sent for histopathological examination regardless of the indication to avoid misdiagnosis and delay in treatment.
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spelling upm-1021332023-08-22T03:36:11Z http://psasir.upm.edu.my/id/eprint/102133/ Mantle Cell Lymphoma Masquerading as obstructive sleep apnoea Ishak, Noor Liza Teng, Tan Sui Mahat, Mahfida Tonsillar malignancy typically presents with asymmetrical tonsillar enlargement, lesion on the tonsils, sore throat or a neck mass. We report a case of unsuspected tonsillar malignancy in a 56-year-old gentleman who presented with symptoms of obstructive sleep apnoea. His tonsils were grade III bilaterally with normal mucosa. Tonsillectomy was performed to improve patient’s compliance with Continuous Positive Airway Pressure (CPAP) therapy. These tonsillar specimens were reported to be Mantle Cell Lymphoma (MCL) based on the histology and ancillary studies. This case highlights that benign-looking symmetrical tonsillar enlargement can harbour occult malignancy. It is important to note that OSA symptoms may be the presentation for haematological malignancies. Tonsillar specimens should be sent for histopathological examination regardless of the indication to avoid misdiagnosis and delay in treatment. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2022 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/102133/1/2023051612005750_MJMHS_0431.pdf Ishak, Noor Liza and Teng, Tan Sui and Mahat, Mahfida (2022) Mantle Cell Lymphoma Masquerading as obstructive sleep apnoea. Malaysian Journal of Medicine and Health Sciences, 19 (3). pp. 390-392. ISSN 1675-8544; ESSN: 2636-9346 https://medic.upm.edu.my/jurnal_kami/volume_19_2023/mjmhs_vol19_no_3_may_2023-72844 10.47836/mjmhs.19.3.51
spellingShingle Ishak, Noor Liza
Teng, Tan Sui
Mahat, Mahfida
Mantle Cell Lymphoma Masquerading as obstructive sleep apnoea
title Mantle Cell Lymphoma Masquerading as obstructive sleep apnoea
title_full Mantle Cell Lymphoma Masquerading as obstructive sleep apnoea
title_fullStr Mantle Cell Lymphoma Masquerading as obstructive sleep apnoea
title_full_unstemmed Mantle Cell Lymphoma Masquerading as obstructive sleep apnoea
title_short Mantle Cell Lymphoma Masquerading as obstructive sleep apnoea
title_sort mantle cell lymphoma masquerading as obstructive sleep apnoea
url http://psasir.upm.edu.my/id/eprint/102133/
http://psasir.upm.edu.my/id/eprint/102133/
http://psasir.upm.edu.my/id/eprint/102133/
http://psasir.upm.edu.my/id/eprint/102133/1/2023051612005750_MJMHS_0431.pdf