Malaysian socio-demographic characteristics, mean haemoglobin levels and BMI distribution of the monthly transfused group (MTG) and non-monthly transfused group (NMTG) thalassemia patients

Background: Thalassemia is a genetic blood disorder characterized by insufficient haemoglobin level due to mutation in the globin chains causing anaemia with iron overload and the most common genetic haemoglobinopathy in Malaysia. They are grouped as transfusion dependent and non-dependent according...

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Main Authors: Mohammed Ibraheem, Shahad, Sathar, Jameela, Seman, Zainina, Khalid, Bahariah
Format: Article
Published: Universidad Tecnica de Manabi 2022
Online Access:http://psasir.upm.edu.my/id/eprint/102120/
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author Mohammed Ibraheem, Shahad
Sathar, Jameela
Seman, Zainina
Khalid, Bahariah
author_facet Mohammed Ibraheem, Shahad
Sathar, Jameela
Seman, Zainina
Khalid, Bahariah
author_sort Mohammed Ibraheem, Shahad
building UPM Institutional Repository
collection Online Access
description Background: Thalassemia is a genetic blood disorder characterized by insufficient haemoglobin level due to mutation in the globin chains causing anaemia with iron overload and the most common genetic haemoglobinopathy in Malaysia. They are grouped as transfusion dependent and non-dependent according to their transfusion requirement. The frequency of thalassemia transfusions can be discriminated further into monthly to non-monthly transfusion group. Objective: To analyze the socio-demographic characteristic, haemoglobin levels and BMI distribution after classifying the thalassemia patients according to monthly transfused group (MTG), non-monthly transfused group (NMTG) and comparing to a healthy individual control group. Methods and Materials: This was a prospective cross-sectional study gathering data on socio-demographic characteristic, haemoglobin levels and BMI distribution of patients with MTG and NMTG thalassemia patients from a thalassemia clinic in Ampang Hospital and comparing them to healthy individuals in Faculty of Medicine and Health Sciences, Universiti Putra Malaysia. The study embarked between August to October 2020. Results: Our study clearly shows in adult thalassemia MTG are predominantly in Malay ethnicity and younger in comparison to NMTG. The mean Hb levels of MTG is lower compared to NMTG regardless of the genotype and phenotype characteristics.
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spelling upm-1021202023-10-04T07:15:24Z http://psasir.upm.edu.my/id/eprint/102120/ Malaysian socio-demographic characteristics, mean haemoglobin levels and BMI distribution of the monthly transfused group (MTG) and non-monthly transfused group (NMTG) thalassemia patients Mohammed Ibraheem, Shahad Sathar, Jameela Seman, Zainina Khalid, Bahariah Background: Thalassemia is a genetic blood disorder characterized by insufficient haemoglobin level due to mutation in the globin chains causing anaemia with iron overload and the most common genetic haemoglobinopathy in Malaysia. They are grouped as transfusion dependent and non-dependent according to their transfusion requirement. The frequency of thalassemia transfusions can be discriminated further into monthly to non-monthly transfusion group. Objective: To analyze the socio-demographic characteristic, haemoglobin levels and BMI distribution after classifying the thalassemia patients according to monthly transfused group (MTG), non-monthly transfused group (NMTG) and comparing to a healthy individual control group. Methods and Materials: This was a prospective cross-sectional study gathering data on socio-demographic characteristic, haemoglobin levels and BMI distribution of patients with MTG and NMTG thalassemia patients from a thalassemia clinic in Ampang Hospital and comparing them to healthy individuals in Faculty of Medicine and Health Sciences, Universiti Putra Malaysia. The study embarked between August to October 2020. Results: Our study clearly shows in adult thalassemia MTG are predominantly in Malay ethnicity and younger in comparison to NMTG. The mean Hb levels of MTG is lower compared to NMTG regardless of the genotype and phenotype characteristics. Universidad Tecnica de Manabi 2022 Article PeerReviewed Mohammed Ibraheem, Shahad and Sathar, Jameela and Seman, Zainina and Khalid, Bahariah (2022) Malaysian socio-demographic characteristics, mean haemoglobin levels and BMI distribution of the monthly transfused group (MTG) and non-monthly transfused group (NMTG) thalassemia patients. International Journal of Health Sciences, 6 (spec.8). 1931 - 1942. ISSN 2550-6978; ESSN: 2550-696X https://sciencescholar.us/journal/index.php/ijhs/article/view/11528 10.53730/ijhs.v6nS8.11528
spellingShingle Mohammed Ibraheem, Shahad
Sathar, Jameela
Seman, Zainina
Khalid, Bahariah
Malaysian socio-demographic characteristics, mean haemoglobin levels and BMI distribution of the monthly transfused group (MTG) and non-monthly transfused group (NMTG) thalassemia patients
title Malaysian socio-demographic characteristics, mean haemoglobin levels and BMI distribution of the monthly transfused group (MTG) and non-monthly transfused group (NMTG) thalassemia patients
title_full Malaysian socio-demographic characteristics, mean haemoglobin levels and BMI distribution of the monthly transfused group (MTG) and non-monthly transfused group (NMTG) thalassemia patients
title_fullStr Malaysian socio-demographic characteristics, mean haemoglobin levels and BMI distribution of the monthly transfused group (MTG) and non-monthly transfused group (NMTG) thalassemia patients
title_full_unstemmed Malaysian socio-demographic characteristics, mean haemoglobin levels and BMI distribution of the monthly transfused group (MTG) and non-monthly transfused group (NMTG) thalassemia patients
title_short Malaysian socio-demographic characteristics, mean haemoglobin levels and BMI distribution of the monthly transfused group (MTG) and non-monthly transfused group (NMTG) thalassemia patients
title_sort malaysian socio-demographic characteristics, mean haemoglobin levels and bmi distribution of the monthly transfused group (mtg) and non-monthly transfused group (nmtg) thalassemia patients
url http://psasir.upm.edu.my/id/eprint/102120/
http://psasir.upm.edu.my/id/eprint/102120/
http://psasir.upm.edu.my/id/eprint/102120/