Kinetic study and model of fermentation parameters affected growth and xylitol production in bioreactor by Kluyveromyces marxianus ATCC 36,907
Optimum conditions for xylitol production from xylose based on the reliable kinetic models of the fermentative performance are important to design lignocellulosic xylitol production. The model was validated by comparing the simulation results with experimental data in batch culture of Kluyveromyces...
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Springer
2022
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| Online Access: | http://psasir.upm.edu.my/id/eprint/102050/ |
| _version_ | 1848863701664268288 |
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| author | Abdul Manaf, Shareena Fairuz Indera Luthfi, Abdullah Amru Tan, Jian Ping Mohamed Abdul, Peer Jamali, Nur Syakina |
| author_facet | Abdul Manaf, Shareena Fairuz Indera Luthfi, Abdullah Amru Tan, Jian Ping Mohamed Abdul, Peer Jamali, Nur Syakina |
| author_sort | Abdul Manaf, Shareena Fairuz |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Optimum conditions for xylitol production from xylose based on the reliable kinetic models of the fermentative performance are important to design lignocellulosic xylitol production. The model was validated by comparing the simulation results with experimental data in batch culture of Kluyveromyces marxianus ATCC 36,907 under various concentrations of initial substrate (36 to 122 g/L) and agitation speed of the impeller (200 to 500 rpm) in a 3.6-L bioreactor. The model suggested that the kinetics of K. marxianus ATCC 36,907 using a modified Monod equation was regulated by the effects of xylose concentrations and oxygen levels during the fermentation. Xylitol production appeared favorable with maximum yield of 0.43 g/g corresponded to kLa value of 29.9 h−1 with low microbial growth. Sensitivity analysis on the obtained model parameters showed that the maximum specific growth rates (µmax) and substrate consumption constant (KS) are the most influential model parameters for xylitol production. |
| first_indexed | 2025-11-15T13:37:06Z |
| format | Article |
| id | upm-102050 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T13:37:06Z |
| publishDate | 2022 |
| publisher | Springer |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1020502023-09-22T23:50:03Z http://psasir.upm.edu.my/id/eprint/102050/ Kinetic study and model of fermentation parameters affected growth and xylitol production in bioreactor by Kluyveromyces marxianus ATCC 36,907 Abdul Manaf, Shareena Fairuz Indera Luthfi, Abdullah Amru Tan, Jian Ping Mohamed Abdul, Peer Jamali, Nur Syakina Optimum conditions for xylitol production from xylose based on the reliable kinetic models of the fermentative performance are important to design lignocellulosic xylitol production. The model was validated by comparing the simulation results with experimental data in batch culture of Kluyveromyces marxianus ATCC 36,907 under various concentrations of initial substrate (36 to 122 g/L) and agitation speed of the impeller (200 to 500 rpm) in a 3.6-L bioreactor. The model suggested that the kinetics of K. marxianus ATCC 36,907 using a modified Monod equation was regulated by the effects of xylose concentrations and oxygen levels during the fermentation. Xylitol production appeared favorable with maximum yield of 0.43 g/g corresponded to kLa value of 29.9 h−1 with low microbial growth. Sensitivity analysis on the obtained model parameters showed that the maximum specific growth rates (µmax) and substrate consumption constant (KS) are the most influential model parameters for xylitol production. Springer 2022-07-12 Article PeerReviewed Abdul Manaf, Shareena Fairuz and Indera Luthfi, Abdullah Amru and Tan, Jian Ping and Mohamed Abdul, Peer and Jamali, Nur Syakina (2022) Kinetic study and model of fermentation parameters affected growth and xylitol production in bioreactor by Kluyveromyces marxianus ATCC 36,907. Biomass Conversion and Biorefinery, 13 (8). pp. 7247-7263. ISSN 2190-6815; ESSN: 2190-6823 https://link.springer.com/article/10.1007/s13399-022-02976-2 10.1007/s13399-022-02976-2 |
| spellingShingle | Abdul Manaf, Shareena Fairuz Indera Luthfi, Abdullah Amru Tan, Jian Ping Mohamed Abdul, Peer Jamali, Nur Syakina Kinetic study and model of fermentation parameters affected growth and xylitol production in bioreactor by Kluyveromyces marxianus ATCC 36,907 |
| title | Kinetic study and model of fermentation parameters affected growth and xylitol production in bioreactor by Kluyveromyces marxianus ATCC 36,907 |
| title_full | Kinetic study and model of fermentation parameters affected growth and xylitol production in bioreactor by Kluyveromyces marxianus ATCC 36,907 |
| title_fullStr | Kinetic study and model of fermentation parameters affected growth and xylitol production in bioreactor by Kluyveromyces marxianus ATCC 36,907 |
| title_full_unstemmed | Kinetic study and model of fermentation parameters affected growth and xylitol production in bioreactor by Kluyveromyces marxianus ATCC 36,907 |
| title_short | Kinetic study and model of fermentation parameters affected growth and xylitol production in bioreactor by Kluyveromyces marxianus ATCC 36,907 |
| title_sort | kinetic study and model of fermentation parameters affected growth and xylitol production in bioreactor by kluyveromyces marxianus atcc 36,907 |
| url | http://psasir.upm.edu.my/id/eprint/102050/ http://psasir.upm.edu.my/id/eprint/102050/ http://psasir.upm.edu.my/id/eprint/102050/ |