In vitro growth inhibition, caspase-dependent apoptosis, and S and G2/M phase arrest in breast cancer cells induced by fluorine-incorporated gold I compound, Ph3PAu[SC(OMe)=NC6H4F-3]
Gold-based anticancer compounds have been attracting increasing research interest due to their ability to kill cancer cells resistant to platinum-based compounds. Gold I- and gold III-based complexes have shown satisfactory anticancer activities. In this study, two new fluorine-incorporated gold (I)...
| Main Authors: | Richard Ming, Chuan Yu, Selvarajah, Gayathri Thevi, Geok, Chin Tan, Yoke, Kqueen Cheah |
|---|---|
| Format: | Article |
| Published: |
Hindawi
2022
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/102002/ |
Similar Items
Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signalling pathways
by: Foo, Jhi Biau, et al.
Published: (2014)
by: Foo, Jhi Biau, et al.
Published: (2014)
Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signaling pathways
by: Foo, Jhi Biau, et al.
Published: (2014)
by: Foo, Jhi Biau, et al.
Published: (2014)
Zerumbone induces apoptosis in Jurkat T-cell line via activation of caspase 3 and caspase 9
by: Rahman, Heshu Sulaiman, et al.
Published: (2012)
by: Rahman, Heshu Sulaiman, et al.
Published: (2012)
G 2 /M cell cycle arrest on HT-29 cancer cells and toxicity assessment of triphenylphosphanegold(I) carbonimidothioates, Ph 3 PAu[SC(OR) = NPh], R = Me, Et, and iPr, during zebrafish development
by: Ooi, Kah Kooi *, et al.
Published: (2017)
by: Ooi, Kah Kooi *, et al.
Published: (2017)
G2/M cell cycle arrest on HT-29 cancer cells and toxicity assessment of triphenylphosphanegold(I) carbonimidothioates, Ph3PAu[SC(OR) = NPh], R = Me, Et, and iPr, during zebrafish development
by: Ooi, Kah Kooi, et al.
Published: (2017)
by: Ooi, Kah Kooi, et al.
Published: (2017)
Caspase-3 and caspase-8 expression in breast cancer: caspase-3 is associated with survival
by: Xuan, Pu, et al.
Published: (2016)
by: Xuan, Pu, et al.
Published: (2016)
Caspases-3 and -7 are activated in goniothalamin-induced apoptosis in human Jurkat T-cells
by: Inayat-Hussain, Salmaan H., et al.
Published: (1999)
by: Inayat-Hussain, Salmaan H., et al.
Published: (1999)
A conformational polymorph of Ph3PAu[SC(OEt)=NPh] featuring an intramolecular Au···π interaction
by: Yeo, Chien Ing *, et al.
Published: (2016)
by: Yeo, Chien Ing *, et al.
Published: (2016)
Cardamonin induces apoptosis in human nasopharyngeal carcinoma cells via mitochondrial death pathway mediated by caspase-3 and caspase-8 activation, independent of caspase-9 signalling responses
by: Chiang, Michelle
Published: (2016)
by: Chiang, Michelle
Published: (2016)
Goniothalamin selectively induces apoptosis on human hepatoblastoma cells through caspase-3 activation.
by: Al-Qubaisi, Mothanna, et al.
Published: (2013)
by: Al-Qubaisi, Mothanna, et al.
Published: (2013)
Clausenidin induces caspase-dependent apoptosis in colon cancer
by: Waziri, Peter M., et al.
Published: (2016)
by: Waziri, Peter M., et al.
Published: (2016)
Pathogenic Gram-positive bacteria are highly sensitive to triphenylphosphanegold(O-alkylthiocarbamates), Ph3PAu[SC(OR)=N(p-tolyl)] (R = Me, Et and iPr)
by: Yeo, Chien Ing, et al.
Published: (2013)
by: Yeo, Chien Ing, et al.
Published: (2013)
Inhibitory Effects Of Andrographolide In Pc-3 Cell Line And The Induction Of Apoptosis Via The Involvement Of Caspases 3, 8 And 9
by: Manimaran, Janany
Published: (2023)
by: Manimaran, Janany
Published: (2023)
Palmitic acid of Musa Paradisiaca induces apoptosis through caspase-3 in human oral squamous cell carcinoma
by: Budi, H. S., et al.
Published: (2022)
by: Budi, H. S., et al.
Published: (2022)
Andrographolide induces cell cycle arrest and apoptosis in PC-3 prostate cancer cells.
by: Hui, Chyn Wong, et al.
Published: (2011)
by: Hui, Chyn Wong, et al.
Published: (2011)
Implications of Wettability Alteration of Sandstone Rocks Using Non-fluorinated scCO2-based Silylation
by: Arjomand, Eghan
Published: (2020)
by: Arjomand, Eghan
Published: (2020)
Caspase-8-mediated PAR-4 cleavage is required for TNFα-induced apoptosis
by: Treude, Fabian, et al.
Published: (2014)
by: Treude, Fabian, et al.
Published: (2014)
Induction of Caspase-2 Activation by a DNA Enzyme Evokes Tumor Cell Apoptosis
by: Kim, Soo-Hyun, et al.
Published: (2012)
by: Kim, Soo-Hyun, et al.
Published: (2012)
The Role Of Caspase-Activated Dnase (Cad) In Chromosome Breaks During Oxidative Stressinduced Apoptosis
by: Boon, Siaw Shi
Published: (2009)
by: Boon, Siaw Shi
Published: (2009)
Canine osteosarcoma: a relevant comparative model for osteosarcoma in man
by: Selvarajah, Gayathri Thevi
Published: (2011)
by: Selvarajah, Gayathri Thevi
Published: (2011)
Comparative aspects of microRNA expression in canine and human cancers
by: Sahabi, Kabiru, et al.
Published: (2018)
by: Sahabi, Kabiru, et al.
Published: (2018)
Induction of selective cytotoxicity and apoptosis in human T4-lymphoblastoid cell line (CEMss) by boesenbergin a isolated from boesenbergia rotunda rhizomes involves mitochondrial pathway, activation of caspase 3 and G2/M phase cell cycle arrest
by: Ng, Kuan Beng, et al.
Published: (2013)
by: Ng, Kuan Beng, et al.
Published: (2013)
Typhonium flagelliforme induces apoptosis in CEMss cells via activation of caspase-9, PARP cleavage and cytochrome c release: Its activation coupled with G0/G1 phase cell cycle arrest.
by: Mohan, Syam, et al.
Published: (2010)
by: Mohan, Syam, et al.
Published: (2010)
Histological Evidence of Adenoid Mast Cells Indicating a Role in Otitis Media with Effusion (OME)
by: Abdullah, Baharuddin
Published: (2001)
by: Abdullah, Baharuddin
Published: (2001)
Histological evidence of adenoid mast cells indicating a role in otitis media with effusion (OME)
by: Abdullah, Baharudin
Published: (2001)
by: Abdullah, Baharudin
Published: (2001)
Mechanisms of cisplatin-induced cell death in malignant mesothelioma cells: Role of inhibitor of apoptosis proteins (IAPs) and caspases
by: Cregan, I., et al.
Published: (2013)
by: Cregan, I., et al.
Published: (2013)
Water extract of brewers' rice induces apoptosis in human colorectal cancer cells via activation of caspase-3 and caspase-8 and downregulates the Wnt/β-catenin downstream signaling pathway in brewers' rice-treated rats with azoxymethane-induced colon carcinogenesis
by: Tan, Bee Ling, et al.
Published: (2015)
by: Tan, Bee Ling, et al.
Published: (2015)
An investigation of p53’s differential activation of cell cycle arrest and apoptosis
by: Zhang, Yuan
Published: (2008)
by: Zhang, Yuan
Published: (2008)
Induction of apoptosis in MCF-7 cells via oxidative stress generation, mitochondria-dependent and caspase-independent pathway by ethyl acetate extract of Dillenia suffruticosa and its chemical profile
by: Tor, Yin Sim, et al.
Published: (2015)
by: Tor, Yin Sim, et al.
Published: (2015)
Arborinine from Glycosmis Pentaphylla (retz.) DC induces apoptosis through activation of Caspase-3/7 in human mammary gland Adenocarcinoma (MCF-7) cell line
by: Mohd Hussain, Nurlaili Najmie, et al.
Published: (2016)
by: Mohd Hussain, Nurlaili Najmie, et al.
Published: (2016)
Advances in chemistry and biological activity of fluorinated 1,3,5-triazines
by: Dolzhenko, Anton, et al.
Published: (2007)
by: Dolzhenko, Anton, et al.
Published: (2007)
Advances in chemistry and biological activity of fluorinated 1,3,5-triazines
by: Dolzhenko, Anton, et al.
Published: (2012)
by: Dolzhenko, Anton, et al.
Published: (2012)
Discovery of a highly active anticancer analogue of cardamonin that acts as an inducer of caspase-dependent apoptosis and modulator of the mTOR pathway
by: Khaled bin Break, Mohammed, et al.
Published: (2018)
by: Khaled bin Break, Mohammed, et al.
Published: (2018)
Zingiber officinale roscoe and Piper betleextracts enhanced the chemopreventive effect against colon cancer cells by targeting caspase-mediated apoptosis
by: Yasmin Anum Mohd Yusof,, et al.
Published: (2022)
by: Yasmin Anum Mohd Yusof,, et al.
Published: (2022)
Antiproliferation and induction of caspase-8-dependent mitochondria-mediated apoptosis by β-tocotrienol in human lung and brain cancer cell lines
by: Lim, Su Wen, et al.
Published: (2014)
by: Lim, Su Wen, et al.
Published: (2014)
Phosphanegold(I) dithiocarbamates, R3PAu[SC(=S)N(iPr)CH2CH2OH] for R=Ph, Cy and Et: role of phosphane-bound R substituents upon in vitro cytotoxicity against MCF-7R breast cancer cells and cell death pathways
by: Jamaludin, Nazzatush Shimar, et al.
Published: (2013)
by: Jamaludin, Nazzatush Shimar, et al.
Published: (2013)
The influence of R substituents in triphenylphosphinegold(I)
carbonimidothioates, Ph 3PAu[SC(OR) = NPh] (R = Me, Et and iPr), upon in vitro cytotoxicity against the HT-29 colon cancer cell line and upon apoptotic pathways
by: Chien, Ing Yeo, et al.
Published: (2013)
by: Chien, Ing Yeo, et al.
Published: (2013)
Pau Kecik Enterprise / Fariesya Mohd Khaizal
by: Fariesya, Mohd Khaizal
Published: (2020)
by: Fariesya, Mohd Khaizal
Published: (2020)
Regulation of p53-, Bcl-2- and Caspase-dependent Signaling Pathway in Xanthorrhizol-induced Apoptosis of HepG2 Hepatoma Cells
by: Tri Handayani,, et al.
Published: (2007)
by: Tri Handayani,, et al.
Published: (2007)
Diagnosis of concurrent Rhodococcosis and adenocarcinoma in a cat
by: Chan, Wei Yee, et al.
Published: (2018)
by: Chan, Wei Yee, et al.
Published: (2018)
Similar Items
-
Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signalling pathways
by: Foo, Jhi Biau, et al.
Published: (2014) -
Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signaling pathways
by: Foo, Jhi Biau, et al.
Published: (2014) -
Zerumbone induces apoptosis in Jurkat T-cell line via activation of caspase 3 and caspase 9
by: Rahman, Heshu Sulaiman, et al.
Published: (2012) -
G 2 /M cell cycle arrest on HT-29 cancer cells and toxicity assessment of triphenylphosphanegold(I) carbonimidothioates, Ph 3 PAu[SC(OR) = NPh], R = Me, Et, and iPr, during zebrafish development
by: Ooi, Kah Kooi *, et al.
Published: (2017) -
G2/M cell cycle arrest on HT-29 cancer cells and toxicity assessment of triphenylphosphanegold(I) carbonimidothioates, Ph3PAu[SC(OR) = NPh], R = Me, Et, and iPr, during zebrafish development
by: Ooi, Kah Kooi, et al.
Published: (2017)