Insights into the pathophysiology of Alzheimer's disease and potential therapeutic targets: a current perspective

QR Code

Insights into the pathophysiology of Alzheimer's disease and potential therapeutic targets: a current perspective

The aging population increases steadily because of a healthy lifestyle and medical advancements in healthcare. However, Alzheimer's disease (AD) is becoming more common and problematic among older adults. AD-related cases show an increasing trend annually, and the younger age population may als...

Full description

Bibliographic Details
Main Authors:	Kesevan, Rajah Kumaran, Yunusa, Suleiman, Perimal, Enoch Kumar, Wahab, Habibah, Muller, Christian P., Hassan, Zurina
Format:	Article
Published:	IOS Press 2023
Online Access:	http://psasir.upm.edu.my/id/eprint/101933/

Similar Items

Insights into the pathophysiology of Alzheimers disease and potential therapeutic targets: a current perspective
by: Rajah Kumaran, Kesevan, et al.
Published: (2023)

Effects Of Syzygium Polyanthum (Wight) Walp. Leaf Extract With Potential Cholinergic Activity On Cognitive Function In Chronic Cerebral Hypoperfusion Rat Model
by: Kumaran, Kesevan Rajah
Published: (2021)

Pathophysiology, histopathology and therapeutic of SARS-CoV-2
by: Noman, Efaq, et al.
Published: (2020)

Insights into the neuropathology of cerebral ischemia and its mechanisms
by: Ahad, Mohamad Anuar, et al.
Published: (2020)

SFRP-mediated Wnt sequestration as a potential therapeutic target for Alzheimer's disease
by: Warrier, Sudha, et al.
Published: (2016)

Chronic Obstructive Pulmonary Disease and Lung Cancer: Underlying Pathophysiology and New Therapeutic Modalities
by: Eapen, M., et al.
Published: (2018)

Genetically-controlled Vesicle-Associated Membrane Protein 1 expression may contribute to Alzheimer’s pathophysiology and susceptibility
by: Sevlever, Daniel, et al.
Published: (2015)

Clinical and cognitive trajectories in cognitively healthy elderly individuals with suspected non-Alzheimer's disease pathophysiology (SNAP) or Alzheimer's disease pathology: a longitudinal study.
by: Burnham, S., et al.
Published: (2016)

Pathophysiology of musculoskeletal infection
by: Mohd Shafri, Mohd Affendi
Published: (2015)

Insights on the characteristics and therapeutic potential of mesenchymal stem cell-derived exosomes for mitigation of Alzheimer’s disease’s pathogenicity: a systematic review
by: Mohammed Yousuf Abdi, Sarah, et al.
Published: (2024)

Therapeutic targeting of the leukaemia microenvironment
by: Kuek, V., et al.
Published: (2021)

Pathophysiology for common retrocochlear disorders
by: Dzulkarnain, Ahmad Aidil Arafat, et al.
Published: (2016)

A thematic review on therapeutic toys and games for the elderly with Alzheimer’s disease
by: You, Donggui, et al.
Published: (2024)

Antinociceptive and Anti-Inflammatory Activities of Zerumbone from Zingiber Zerumbet (l.) Roscoe ex sm., and its Possible Mechanisms of Action
by: Perimal, Enoch Kumar
Published: (2012)

New therapeutic targets for osteoarthritis pain
by: Walsh, David A., et al.
Published: (2017)

Novel therapeutic targets in rheumatoid arthritis
by: Sakthiswary Rajalingham,
Published: (2018)

Pathophysiology of non-specific arm pain
by: Moloney, N., et al.
Published: (2011)

Tubulin and tau: Possible targets for diagnosis of Parkinson’s and Alzheimer’s diseases
by: Salama, Mohamed, et al.
Published: (2018)

The therapeutic and psychosocial interaction in enhancing drug targets
by: Musa, Ramli, et al.
Published: (2018)

The future of osteoarthritis therapeutics: targeted pharmacological therapy
by: Mobasheri, Ali
Published: (2013)

Latrepirdine: Molecular mechanisms underlying potential therapeutic roles in Alzheimer’s and other neurodegenerative diseases
by: Bharadwaj, P., et al.
Published: (2013)

Clearance mechanisms of Alzheimer’s amyloid-b peptide: implications for therapeutic design and diagnostic tests
by: Bates, K., et al.
Published: (2009)

Apolipoprotein C-III: From Pathophysiology to Pharmacology
by: Norata, Giuseppe, et al.
Published: (2015)

Transparent insights into alzheimer’s progression: a time-aware approach with explainable
by: Abraham Varghese,, et al.
Published: (2024)

NHE-1: A promising target for novel anti-cancer therapeutics
by: Loo, S., et al.
Published: (2012)

Brain insulin resistance in down syndrome: involvement of PI3K-AKT/MTOR axis in early-onset of Alzheimer's disease and its potential as a therapeutic target
by: Azimzadeh, Mansour, et al.
Published: (2024)

Therapeutic targeting of p53-mediated apoptosis pathway in head and neck squamous cell carcinomas: current progress and challenges
by: Arief Ichwan, Solachuddin Jauhari, et al.
Published: (2012)

Insights into the Biology and Therapeutic Applications of Neural Stem Cells
by: Harris, L., et al.
Published: (2016)

Cyclin dependent Kinases as potential therapeutic targets for atherosclerosis
by: Rostam, Muhamad Ashraf, et al.
Published: (2015)

Identification of potential therapeutic targets for Streptococcus suis infection
by: Jeffreys, Bethan
Published: (2021)

Breast cancer bone metastases: pathogenesis and therapeutic targets
by: Brook, Naomi, et al.
Published: (2018)

Therapeutic targets on toxoplasma gondii parasite in combatting toxoplasmosis
by: Abdullahi, Sharif Alhassan, et al.
Published: (2019)

Phytochemicals and potential therapeutic targets on toxoplasma gondii parasite
by: Abdullahi, Sharif Alhassan, et al.
Published: (2020)

Therapeutic potential of gambogic acid, a caged xanthone, to target cancer
by: Banik, K., et al.
Published: (2018)

Dissecting the physiology and pathophysiology of glucagon-like peptide-1
by: Paternoster, Silvano, et al.
Published: (2018)

Pathophysiologic and prognostic role of cytokines in dengue hemorrhagic fever.
by: Bethell, Delia B., et al.
Published: (1998)

Uncovering incontinentia pigmenti: From DNA sequence to pathophysiology
by: Kang, Nien How, et al.
Published: (2022)

PPARγ disease gene network and identification of therapeutic targets for prostate cancer
by: Venkatachalam, G., et al.
Published: (2011)

Investigating Current Delivery Vehicles for Efficient and Targeted Delivery of Therapeutic RNA and Future Perspectives Part A - Investigating current delivery vehicles for efficient and targeted delivery of therapeutic RNA and future perspectives/ Part B - The development of novel polymeric nanoparticles as efficient non-viral RNA delivery vectors
by: Sachan, Isha
Published: (2023)

Targeting Microglia as a Therapeutic Approach to Treat Neuroinflammatory Disorders
by: Almalki, Masi
Published: (2025)