Melanoma metastasis: what role does melanin play? (review)

QR Code

Melanoma metastasis: what role does melanin play? (review)

Melanoma is an extremely aggressive form of skin cancer that can spread to the lungs, brain, and liver, among other vital organs. Melanoma cells, unlike any other cancer cells, can produce significant amounts of melanin by a process known as melanogenesis, causing them to become heavily pigmented. M...

Full description

Bibliographic Details
Main Authors:	Saud, Anoosha, Sagineedu, Sreenivasa R., Ng, Hui-Suan, Stanslas, Johnson, Chee, Jonathan Woei Lim
Format:	Article
Published:	Spandidos publication 2022
Online Access:	http://psasir.upm.edu.my/id/eprint/101842/

Similar Items

MCAM in Melanoma Metastasis: The Role of Putative Endocytosis Motifs
by: Harfield, Jake
Published: (2021)

Effects of flavokawain a on Interleukin-6 and melanin productions in histamine-induced HaCat keratinocytes cells and mouse B16-F10 melanoma cells
by: Kim, Ji Man
Published: (2015)

SRS06, a new semisynthetic andrographolide derivative with improved anticancer potency and selectivity, inhibits nuclear factor-kB nuclear binding in the A549 non-small cell lung cancer cell line
by: Lim, Jonathan Chee Woei, et al.
Published: (2015)

Pharmacological modulation of apoptosis and autophagy in pancreatic cancer treatment
by: Stanslas, Johnson, et al.
Published: (2022)

Advances and challenges in developing andrographolide and its analogues as cancer therapeutic agents
by: Soo, Hon Liong, et al.
Published: (2019)

LRG1 promotes metastatic dissemination of melanoma through regulating EGFR/STAT3 signalling
by: Kwan, Yuet Ping, et al.
Published: (2021)

Targeting inflammation in non-small cell lung cancer through drug repurposing
by: Rajasegaran, Thiviyadarshini, et al.
Published: (2023)

Andrographolide as a template in the synthesis of new anticancer agents with potentially novel molecular targets
by: Stanslas, Johnson, et al.
Published: (2010)

SRJ09, a promising anticancer drug lead: elucidation of mechanisms of antiproliferative and apoptogenic effects and assessment of in vivo antitumor efficacy
by: Wong, Charng Choon, et al.
Published: (2016)

Phytochemicals from Phyllanthus niruri Linn. and their pharmacological properties: a review
by: Bagalkotkar, Gururaj, et al.
Published: (2006)

Primary Malignant Melanoma of Vagina: The Options of Management.
by: Ng, BK, et al.
Published: (2014)

A novel S-sulfhydrated human serum albumin preparation suppresses melanin synthesis
by: Ikeda, M., et al.
Published: (2018)

Melanin characterisation suggests that the “brown” phenotype in alpaca (Vicugna pacos) is predominantly pheomelanic
by: Cransberg, Rhys, et al.
Published: (2013)

Melanin determination using optimised inverse Monte Carlo for skin - light interaction
by: Mohamad Hani, Ahmad Fadzil, et al.
Published: (2012)

Pericytes in Metastasis
by: Pieterse, Z., et al.
Published: (2019)

Metastasis within a metastasis to the thyroid: A rare phenomenon
by: Wong, Yin PIng, et al.
Published: (2017)

Understanding Proteolytic Processing of Melanoma Cell Adhesion Molecule (MCAM) in Cutaneous Melanoma
by: George, Tenielle
Published: (2023)

Andrographolide induces cell cycle arrest and apoptosis in PC-3 prostate cancer cells.
by: Hui, Chyn Wong, et al.
Published: (2011)

What role does Fintech play in the banking industry today and how do banks have to adjust to it?
by: Zuern, Yannick
Published: (2019)

Evaluation of gingival melanin depigmentation by using Er:YAG laser: ex-vivo and clinical studies
by: Stas, Yasser Tharwat
Published: (2018)

Anorectal melanoma – a report
by: Raja, Hisham, et al.
Published: (2006)

A non-canonical melanin biosynthesis pathway protects Aspergillus terreus conidia from environmental stress
by: Geib, Elena, et al.
Published: (2016)

The association of host and genetic melanoma risk factors with Breslow thickness in the Western Australian Melanoma Health Study
by: Cadby, G., et al.
Published: (2014)

Visual inspection for the diagnosis of cutaneous melanoma in adults
by: Dinnes, Jacqueline, et al.
Published: (2018)

Phyllanthus inhibits proliferation, metastasis, angiogenesis and induces apoptosis of human melanoma (mewo) and prostate adenocarcinoma (pc-3) cells through modulation of multiple cell signalling pathways / Tang Yin Quan
by: Tang, Yin Quan
Published: (2013)

Lymphovascular invasion in melanoma and breast cancer
by: Safuan, Sabreena
Published: (2012)

The Interaction Between Melanoma and Psychiatric Disorder
by: Kisely, S., et al.
Published: (2011)

Non-melanocytic skin cancers and melanoma
by: Ellis, Isabelle, et al.
Published: (2014)

A case of primary colonic melanoma
by: Tee, Shwu Hoon, et al.
Published: (2016)

SRJ23, a new semisynthetic andrographolide derivative: in vitro growth inhibition and mechanisms of cell cycle arrest and apoptosis in prostate cancer cells
by: Wong, Hui Chyn, et al.
Published: (2014)

Molecular and immunomodulatory actions of new antiasthmatic agents: exploring the diversity of biologics in Th2 endotype asthma
by: Okwuofu, Emmanuel Oshiogwe, et al.
Published: (2022)

Phosphopantetheinyl transferase (Ppt)-mediated biosynthesis of lysine, but not siderophores or DHN melanin, is required for virulence of Zymoseptoria tritici on wheat
by: Derbyshire, Mark, et al.
Published: (2018)

Reflectance confocal microscopy for diagnosing cutaneous melanoma in adults
by: Dinnes, Jacqueline, et al.
Published: (2018)

Dermoscopy, with and without visual inspection, for the diagnosis of melanoma in adults
by: Dinnes, Jacqueline, et al.
Published: (2018)

Determination of melanin types and relative concentrations: an observational study using a non-invasive inverse skin reflectance analysis
by: Mohd Hani, Ahmad Fadzil, et al.
Published: (2014)

Ubiquitination and adaptive responses to BRAF inhibitors in Melanoma
by: Saei, A., et al.
Published: (2018)

Melanoma biomolecules: Independently identified but functionally intertwined
by: Dye, Danielle, et al.
Published: (2013)

Association between in-vitro fertilization, birth and melanoma
by: Stewart, Louise, et al.
Published: (2013)

More than just a KRAS inhibitor: DCAI abrogates the self-renewal of pancreatic cancer stem cells in vitro
by: Yuan, Han Teh, et al.
Published: (2023)

Smartphone applications for triaging adults with skin lesions that are suspicious for melanoma
by: Chuchu, Naomi, et al.
Published: (2018)