Exploring the phytochemicals and anti-cancer potential of the members of fabaceae family: a comprehensive review
Cancer is the second-ranked disease and a cause of death for millions of people around the world despite many kinds of available treatments. Phytochemicals are considered a vital source of cancer-inhibiting drugs and utilize specific mechanisms including carcinogen inactivation, the induction of cel...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
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MDPI AG
2022
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| Online Access: | http://psasir.upm.edu.my/id/eprint/101416/ |
| _version_ | 1848863555233775616 |
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| author | Muhammad Usman Waseem Razzaq Khan Yousaf, Nousheen Akram, Seemab Murtaza, Ghulam Abdul Kudus, Kamziah Ditta, Allah Rosli, Zamri Rajpar, Muhammad Nawaz Mohd Nazre, . |
| author_facet | Muhammad Usman Waseem Razzaq Khan Yousaf, Nousheen Akram, Seemab Murtaza, Ghulam Abdul Kudus, Kamziah Ditta, Allah Rosli, Zamri Rajpar, Muhammad Nawaz Mohd Nazre, . |
| author_sort | Muhammad Usman |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Cancer is the second-ranked disease and a cause of death for millions of people around the world despite many kinds of available treatments. Phytochemicals are considered a vital source of cancer-inhibiting drugs and utilize specific mechanisms including carcinogen inactivation, the induction of cell cycle arrest, anti-oxidant stress, apoptosis, and regulation of the immune system. Family Fabaceae is the second most diverse family in the plant kingdom, and species of the family are widely distributed across the world. The species of the Fabaceae family are rich in phytochemicals (flavonoids, lectins, saponins, alkaloids, carotenoids, and phenolic acids), which exhibit a variety of health benefits, especially anti-cancer properties; therefore, exploration of the phytochemicals present in various members of this family is crucial. These phytochemicals of the Fabaceae family have not been explored in a better way yet; therefore, this review is an effort to summarize all the possible information related to the phytochemical status of the Fabaceae family and their anti-cancer properties. Moreover, various research gaps have been identified with directions for future research. |
| first_indexed | 2025-11-15T13:34:47Z |
| format | Article |
| id | upm-101416 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T13:34:47Z |
| publishDate | 2022 |
| publisher | MDPI AG |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1014162023-06-08T02:29:43Z http://psasir.upm.edu.my/id/eprint/101416/ Exploring the phytochemicals and anti-cancer potential of the members of fabaceae family: a comprehensive review Muhammad Usman Waseem Razzaq Khan Yousaf, Nousheen Akram, Seemab Murtaza, Ghulam Abdul Kudus, Kamziah Ditta, Allah Rosli, Zamri Rajpar, Muhammad Nawaz Mohd Nazre, . Cancer is the second-ranked disease and a cause of death for millions of people around the world despite many kinds of available treatments. Phytochemicals are considered a vital source of cancer-inhibiting drugs and utilize specific mechanisms including carcinogen inactivation, the induction of cell cycle arrest, anti-oxidant stress, apoptosis, and regulation of the immune system. Family Fabaceae is the second most diverse family in the plant kingdom, and species of the family are widely distributed across the world. The species of the Fabaceae family are rich in phytochemicals (flavonoids, lectins, saponins, alkaloids, carotenoids, and phenolic acids), which exhibit a variety of health benefits, especially anti-cancer properties; therefore, exploration of the phytochemicals present in various members of this family is crucial. These phytochemicals of the Fabaceae family have not been explored in a better way yet; therefore, this review is an effort to summarize all the possible information related to the phytochemical status of the Fabaceae family and their anti-cancer properties. Moreover, various research gaps have been identified with directions for future research. MDPI AG 2022-06-16 Article PeerReviewed Muhammad Usman and Waseem Razzaq Khan and Yousaf, Nousheen and Akram, Seemab and Murtaza, Ghulam and Abdul Kudus, Kamziah and Ditta, Allah and Rosli, Zamri and Rajpar, Muhammad Nawaz and Mohd Nazre, . (2022) Exploring the phytochemicals and anti-cancer potential of the members of fabaceae family: a comprehensive review. Molecules, 27 (12). art. no. 3863. pp. 1-21. ISSN 1431-5165; ESSN: 1420-3049 https://www.mdpi.com/1420-3049/27/12/3863 10.3390/molecules27123863 |
| spellingShingle | Muhammad Usman Waseem Razzaq Khan Yousaf, Nousheen Akram, Seemab Murtaza, Ghulam Abdul Kudus, Kamziah Ditta, Allah Rosli, Zamri Rajpar, Muhammad Nawaz Mohd Nazre, . Exploring the phytochemicals and anti-cancer potential of the members of fabaceae family: a comprehensive review |
| title | Exploring the phytochemicals and anti-cancer potential of the members of fabaceae family: a comprehensive review |
| title_full | Exploring the phytochemicals and anti-cancer potential of the members of fabaceae family: a comprehensive review |
| title_fullStr | Exploring the phytochemicals and anti-cancer potential of the members of fabaceae family: a comprehensive review |
| title_full_unstemmed | Exploring the phytochemicals and anti-cancer potential of the members of fabaceae family: a comprehensive review |
| title_short | Exploring the phytochemicals and anti-cancer potential of the members of fabaceae family: a comprehensive review |
| title_sort | exploring the phytochemicals and anti-cancer potential of the members of fabaceae family: a comprehensive review |
| url | http://psasir.upm.edu.my/id/eprint/101416/ http://psasir.upm.edu.my/id/eprint/101416/ http://psasir.upm.edu.my/id/eprint/101416/ |