Detection of neuroendocrine tumour of sphenoid sinus on the Gallium-68 DOTATATE PET/CT: a rare entity
Neuroendocrine tumours (NETs) are a category of neoplasm that is characterised by its phenotypic and heterogeneity. The occurrence of this type of neoplasm in the nasal cavity and paranasal sinuses is extremely rare accounting for only 0.2-0.8% of all cancers. NET tends to expresses somatostatin rec...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Faculty of Medicine and Health Sciences, University Putra Malaysia
2022
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| Online Access: | http://psasir.upm.edu.my/id/eprint/100918/ http://psasir.upm.edu.my/id/eprint/100918/1/Detection%20of%20neuroendocrine%20tumour%20of%20sphenoid%20sinus.pdf |
| _version_ | 1848863447312236544 |
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| author | Shamim, Syed Ejaz Khairuman, Khairul Aliff Abdul Onny, Muhammad Adib Mohd Yusoff, Suryati Ahmad Saad, Fathinul Fikri |
| author_facet | Shamim, Syed Ejaz Khairuman, Khairul Aliff Abdul Onny, Muhammad Adib Mohd Yusoff, Suryati Ahmad Saad, Fathinul Fikri |
| author_sort | Shamim, Syed Ejaz |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Neuroendocrine tumours (NETs) are a category of neoplasm that is characterised by its phenotypic and heterogeneity. The occurrence of this type of neoplasm in the nasal cavity and paranasal sinuses is extremely rare accounting for only 0.2-0.8% of all cancers. NET tends to expresses somatostatin receptors (SSTR) and owning to this unique characteristic, molecular imaging has been able to detect these tumours using radiolabelled somatostatin analogue agent. Gallium-68 (Ga-68) DOTATATE PET/CT is an example of SSTR imaging and has been shown to be of importance in the assessment and staging of NET. We present a case of a rare sphenoid sinus NET in a 45-year-old gentleman whom initially presented with persistent left eye pain which led to visual loss. We described the utilization of Ga-68 DOTATATE PET/CT in the diagnosis and staging of this patient which in turn dictated treatment approach. |
| first_indexed | 2025-11-15T13:33:04Z |
| format | Article |
| id | upm-100918 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T13:33:04Z |
| publishDate | 2022 |
| publisher | Faculty of Medicine and Health Sciences, University Putra Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1009182023-07-14T08:55:04Z http://psasir.upm.edu.my/id/eprint/100918/ Detection of neuroendocrine tumour of sphenoid sinus on the Gallium-68 DOTATATE PET/CT: a rare entity Shamim, Syed Ejaz Khairuman, Khairul Aliff Abdul Onny, Muhammad Adib Mohd Yusoff, Suryati Ahmad Saad, Fathinul Fikri Neuroendocrine tumours (NETs) are a category of neoplasm that is characterised by its phenotypic and heterogeneity. The occurrence of this type of neoplasm in the nasal cavity and paranasal sinuses is extremely rare accounting for only 0.2-0.8% of all cancers. NET tends to expresses somatostatin receptors (SSTR) and owning to this unique characteristic, molecular imaging has been able to detect these tumours using radiolabelled somatostatin analogue agent. Gallium-68 (Ga-68) DOTATATE PET/CT is an example of SSTR imaging and has been shown to be of importance in the assessment and staging of NET. We present a case of a rare sphenoid sinus NET in a 45-year-old gentleman whom initially presented with persistent left eye pain which led to visual loss. We described the utilization of Ga-68 DOTATATE PET/CT in the diagnosis and staging of this patient which in turn dictated treatment approach. Faculty of Medicine and Health Sciences, University Putra Malaysia 2022-05 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/100918/1/Detection%20of%20neuroendocrine%20tumour%20of%20sphenoid%20sinus.pdf Shamim, Syed Ejaz and Khairuman, Khairul Aliff and Abdul Onny, Muhammad Adib and Mohd Yusoff, Suryati and Ahmad Saad, Fathinul Fikri (2022) Detection of neuroendocrine tumour of sphenoid sinus on the Gallium-68 DOTATATE PET/CT: a rare entity. Malaysian Journal of Medicine and Health Sciences, 18 (3). art. no. 28. 192 - 194. ISSN 2636-9346 https://medic.upm.edu.my/jurnal_kami/volume_18_2022/mjmhs_vol18_no_3_may_2022-66847 |
| spellingShingle | Shamim, Syed Ejaz Khairuman, Khairul Aliff Abdul Onny, Muhammad Adib Mohd Yusoff, Suryati Ahmad Saad, Fathinul Fikri Detection of neuroendocrine tumour of sphenoid sinus on the Gallium-68 DOTATATE PET/CT: a rare entity |
| title | Detection of neuroendocrine tumour of sphenoid sinus on the Gallium-68 DOTATATE PET/CT: a rare entity |
| title_full | Detection of neuroendocrine tumour of sphenoid sinus on the Gallium-68 DOTATATE PET/CT: a rare entity |
| title_fullStr | Detection of neuroendocrine tumour of sphenoid sinus on the Gallium-68 DOTATATE PET/CT: a rare entity |
| title_full_unstemmed | Detection of neuroendocrine tumour of sphenoid sinus on the Gallium-68 DOTATATE PET/CT: a rare entity |
| title_short | Detection of neuroendocrine tumour of sphenoid sinus on the Gallium-68 DOTATATE PET/CT: a rare entity |
| title_sort | detection of neuroendocrine tumour of sphenoid sinus on the gallium-68 dotatate pet/ct: a rare entity |
| url | http://psasir.upm.edu.my/id/eprint/100918/ http://psasir.upm.edu.my/id/eprint/100918/ http://psasir.upm.edu.my/id/eprint/100918/1/Detection%20of%20neuroendocrine%20tumour%20of%20sphenoid%20sinus.pdf |