Cytotoxicity and 1H NMR metabolomics analyses of microalgal extracts for synergistic application with Tamoxifen on breast cancer cells with reduced toxicity against Vero cells

QR Code

Cytotoxicity and 1H NMR metabolomics analyses of microalgal extracts for synergistic application with Tamoxifen on breast cancer cells with reduced toxicity against Vero cells

This study evaluated the cytotoxic activity of Tamoxifen (TMX), an anti-estrogen drug, with microalgal crude extracts (MCEs) in single and synergistic application (TMX-MCEs) on MCF-7 and 4T1 breast cancer cells, and non-cancerous Vero cells. The MCEs of Nannochloropsis oculata, Tetraselmis suecica a...

Full description

Bibliographic Details
Main Authors:	Ali Hussein, Hanaa, Kassim, Murni Nur Islamiah, Maulidiani, M., Abas, Faridah, Abdullah, Mohd Azmuddin
Format:	Article
Published:	Elsevier 2022
Online Access:	http://psasir.upm.edu.my/id/eprint/100867/

Similar Items

NMR metabolomics for evaluating passage number and harvesting effects on mammalian cell metabolome
by: Abdul Hamid, Nur Ashikin, et al.
Published: (2019)

Nordamnacanthal potentiates the cytotoxic effects of tamoxifen in human breast cancer cells
by: Mohamed Alitheen, Noorjahan Banu, et al.
Published: (2015)

Toxicity studies of natural product in vero cells using impedance monitoring
by: Hamdan, Taufik Hakim, et al.
Published: (2017)

Synergistic cytotoxicity between elephantopus scaber and tamoxifen on MCF-7-derived multicellular tumor spheroid
by: Ho, Wan Yong, et al.
Published: (2021)

Cytotoxicity of selected organotin (IV) compounds on vero and caov-3 cell lines
by: Siti Farizah, Wagimen
Published: (2010)

Metabolite profiling of the microalgal diatom Chaetoceros calcitrans and correlation with antioxidant and nitric oxide inhibitory activities via 1H NMR-based metabolomics
by: Azizan, Awanis, et al.
Published: (2018)

Cytotoxicity Effect Of Cymbopogon Nardus Methanolic Fraction Against Vero And Caov3 Cells
by: Reagan Entigu, Linton @ Jerah, et al.
Published: (2012)

Toxicity studies of agarwood essential oil in vero cells using electrical impedance sensor
by: Mohd Mansor, Ahmad Fairuzabadi, et al.
Published: (2017)

Toxicity effect of mixture of selected Malaysia herbs in cultured Vero and WRL-68 cells
by: Hazali, Norazlanshah, et al.
Published: (2011)

Hippurate-Zinc layered Hydroxide Nanohybrid and its synergistic effect with Tamoxifen on the HepG2 cell lines.
by: Hussein, Mohd. Zobir, et al.
Published: (2011)

Cytotoxicity of tamoxifen-loaded solid lipd nanoparticles
by: Abbasalipourkabirreh, Roghayeh, et al.
Published: (2012)

Mass spectrometry-based metabolomics combined with quantitative analysis of the microalgal diatom (Chaetoceros calcitrans)
by: Azizan, Awanis, et al.
Published: (2020)

The vero cells growth in different type of microcarriers
by: Ahmad Nor, Yusilawati, et al.
Published: (2011)

Bioactive compounds of pigmented rice extracts reveal by NMR-based metabolomics
by: Netrprachit, Papichaya, et al.
Published: (2023)

Microalgal cell disruption for biofuel development
by: Halim, R., et al.
Published: (2012)

The growth study of vero cells in different type of microcarrier
by: Ahmad Nor, Yusilawati, et al.
Published: (2010)

Hematological, biochemical, histopathological and 1H-NMR metabolomics application in acute toxicity evaluation of clinacanthus nutans water leaf extract
by: Leng, Wei Khoo, et al.
Published: (2018)

Cytotoxicity and apoptotic DNA fragmentation evaluation of ethanolic extract of Phyllanthus niruri L. in Vero and primary feline testicular cells
by: Roslan, Rasydan Hadi, et al.
Published: (2024)

Efficient performance of locally processed serum in vero cell culture
by: Ahmad Nor, Yusilawati, et al.
Published: (2011)

Biocompatibility of porous hydroxyapatite microcarrier for vero cell culture application
by: Mel, Maizirwan, et al.
Published: (2011)

Ultrastructural aspects of sylvatic dengue virus infection in Vero cell
by: Low, Fish Cheng Yee, et al.
Published: (2019)

Discrimination of Ipomoea aquatica cultivars and bioactivity correlations using NMR-based metabolomics approach
by: Lawal, Umar, et al.
Published: (2017)

Discrimination of Ipomoea aquatica cultivars and bioactivity correlations using NMR-based metabolomics approach
by: Lawal, U., et al.
Published: (2017)

1H NMR-metabolomics studies on acute toxicity effect of lead in adult zebrafish (Danio rerio) model
by: Chong, Siok Geok, et al.
Published: (2024)

Vero cell culture on magnesium doped biphasic calcium phosphate scaffolds
by: Abd Rahim, Toibah, et al.
Published: (2016)

Locally processed serum performance in vero cell culture: Part I
by: Ahmad Nor, Yusilawati, et al.
Published: (2011)

Locally processed serum performance in vero cell culture: Part II
by: Ahmad Nor, Yusilawati, et al.
Published: (2011)

Molecular identification of dengue virus binding protein on filopodia of vero cells
by: Aliyu, Isah Abubakar
Published: (2017)

Vitamin C suppresses cell death in MCF-7 breast cancer cells induced by tamoxifen
by: Subramani, Tamilselvan, et al.
Published: (2012)

1H-NMR-based metabolomics approach to understanding the drying effects on the phytochemicals in Cosmos caudatus
by: Mediani, Ahmed, et al.
Published: (2012)

Development, characterization, cytotoxicity and antitumor effect of tamoxifen-loaded solid lipid nanoparticles
by: Abbasalipourkabirreh, Roghayeh
Published: (2010)

Optimization of serum preparation in Vero cell culture using a statistical approach
by: Ahmad Nor, Yusilawati, et al.
Published: (2009)

The effect of hydroxyapatite addition on biocompatibility of porous alumina microcarriers for vero cell culture
by: Fadli, Ahmad, et al.
Published: (2011)

Phytochemical and bioactivity alterations of Curcuma species harvested at different growth stages by NMR-based metabolomics
by: Awin, Tahani M., et al.
Published: (2019)

Vitamin C suppresses cell death in MCF-7 human breast cancer cells induced by tamoxifen
by: Subramani, Tamilselvan, et al.
Published: (2014)

Comparison of chikungunya virus culture propagated in two cell line; vero and C6/36 cell lines
by: Ridzwanurahim, bin Nazimudin
Published: (2015)

Physicochemical investigation of microalgal cell disruption technologies with energy consumption analysis
by: Harun, R., et al.
Published: (2013)

Microalgal cell disruption and lipid extraction techniques for potential biofuel production
by: Karim, Ahasanul, et al.
Published: (2019)

Antioxidant potential and Cancer-specific cytotoxic effect of selected marine microalgal extratcs
by: Ferdous, Umme Tamanna
Published: (2023)

Zinc layered hydroxide-salicylate nanohybrid and its effect on Vero3 cells viability.
by: Ramli, Munirah, et al.