CRISPR-Cas knockout of miR21 reduces glioma growth

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CRISPR-Cas knockout of miR21 reduces glioma growth

Non-coding RNAs, including microRNAs (miRNAs), support the progression of glioma. miR-21 is a small, non-coding transcript involved in regulating gene expression in multiple cellular pathways, including the regulation of proliferation. High expression of miR-21 has been shown to be a major driver of...

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Bibliographic Details
Main Authors:	Nieland, Lisa, Solinge, Thomas S. van, Cheah, Pike See, Morsett, Liza M., Khoury, Joseph El, Rissman, Joseph I., Kleinstiver, Benjamin P., Broekman, Marike L. D., Breakefield, Xandra O., Abels, Erik R.
Format:	Article
Published:	Cell Press 2022
Online Access:	http://psasir.upm.edu.my/id/eprint/100836/

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