Association of endothelin-converting enzyme and endothelin-1 gene polymorphisms with essential hypertension in Malay ethnics

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Association of endothelin-converting enzyme and endothelin-1 gene polymorphisms with essential hypertension in Malay ethnics

Objectives. Endothelin-1 (ET-1), the most potent endogenous vasoconstrictor, generated by enzymatic cleavage catalyzed by an endothelin-converting enzyme (ECE), plays a significant role in the regulation of hypertension. Methods. This study investigates the effect of endothelin-1 (Lys198Asn/rs5370)...

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Bibliographic Details
Main Authors:	Salim, Elnaz, Ramachandran, Vasudevan, Ansari, Neda, Ismail, Patimah, Mohamed, Mohd Hazmi, Mohamad, Nur Afiqah, Inche Mat, Liyana Najwa
Format:	Article
Published:	Cambridge University Press 2022
Online Access:	http://psasir.upm.edu.my/id/eprint/100425/

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