A rare case of hepatic flexure Gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC)
A Colorectal neuroendocrine carcinoma (CRNEC) is a rare malignancy of the colon. It is a tumour with a heterogeneous presentation, further complicated by its disunified nomenclature, which imposed a challenge in detection and management. We present a rare case of hepatic flexure neuroendocrine carci...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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UPM Press
2022
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| Online Access: | http://psasir.upm.edu.my/id/eprint/100345/ http://psasir.upm.edu.my/id/eprint/100345/1/A%20rare%20case%20of%20hepatic%20flexure%20Gastroenteropancreatic%20neuroendocrine%20carcinoma%20%28GEP-NEC%29.pdf |
| _version_ | 1848863300597579776 |
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| author | Jasmani, Asraf Haslam Khazalle, Muhammad Haekal Oaris, Iqtidaar Mohamad, Ikhwan Sani |
| author_facet | Jasmani, Asraf Haslam Khazalle, Muhammad Haekal Oaris, Iqtidaar Mohamad, Ikhwan Sani |
| author_sort | Jasmani, Asraf Haslam |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | A Colorectal neuroendocrine carcinoma (CRNEC) is a rare malignancy of the colon. It is a tumour with a heterogeneous presentation, further complicated by its disunified nomenclature, which imposed a challenge in detection and management. We present a rare case of hepatic flexure neuroendocrine carcinoma in a 47-year-old lady who complained of 5 months history of progressively worsening, intermittent colicky central abdominal pain, altered bowel habit, vomiting, and significant weight loss. She presented with lethargy, distended abdomen and fullness at its centre. The abdominal x-ray showed generalised bowel dilatation, with the subsequent CT scan abdomen showing obstructed hepatic flexure tumour. She underwent emergency exploratory laparotomy and right hemicolectomy with a double-barrel stoma. Intraoperatively, a hepatic flexure tumour, an engorged and nodular appendix with multiple mesenteric lymph nodes. Her recovery was unremarkable. Histopathology examination showed neuroendocrine tumour Grade 3 arising from hepatic flexure with no appendiceal involvement. |
| first_indexed | 2025-11-15T13:30:44Z |
| format | Article |
| id | upm-100345 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T13:30:44Z |
| publishDate | 2022 |
| publisher | UPM Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1003452023-12-26T07:33:14Z http://psasir.upm.edu.my/id/eprint/100345/ A rare case of hepatic flexure Gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC) Jasmani, Asraf Haslam Khazalle, Muhammad Haekal Oaris, Iqtidaar Mohamad, Ikhwan Sani A Colorectal neuroendocrine carcinoma (CRNEC) is a rare malignancy of the colon. It is a tumour with a heterogeneous presentation, further complicated by its disunified nomenclature, which imposed a challenge in detection and management. We present a rare case of hepatic flexure neuroendocrine carcinoma in a 47-year-old lady who complained of 5 months history of progressively worsening, intermittent colicky central abdominal pain, altered bowel habit, vomiting, and significant weight loss. She presented with lethargy, distended abdomen and fullness at its centre. The abdominal x-ray showed generalised bowel dilatation, with the subsequent CT scan abdomen showing obstructed hepatic flexure tumour. She underwent emergency exploratory laparotomy and right hemicolectomy with a double-barrel stoma. Intraoperatively, a hepatic flexure tumour, an engorged and nodular appendix with multiple mesenteric lymph nodes. Her recovery was unremarkable. Histopathology examination showed neuroendocrine tumour Grade 3 arising from hepatic flexure with no appendiceal involvement. UPM Press 2022-10 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/100345/1/A%20rare%20case%20of%20hepatic%20flexure%20Gastroenteropancreatic%20neuroendocrine%20carcinoma%20%28GEP-NEC%29.pdf Jasmani, Asraf Haslam and Khazalle, Muhammad Haekal and Oaris, Iqtidaar and Mohamad, Ikhwan Sani (2022) A rare case of hepatic flexure Gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC). Malaysian Journal of Medicine and Health Sciences, 18 (suppl. 13). art. no. 6. 21 - 24. ISSN 2636-9346 https://medic.upm.edu.my/our_journal/volume_18_2022/mjmhs_vol18_supp_13_oktober_2022-69861 10.47836/mjmhs18.s13.7 |
| spellingShingle | Jasmani, Asraf Haslam Khazalle, Muhammad Haekal Oaris, Iqtidaar Mohamad, Ikhwan Sani A rare case of hepatic flexure Gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC) |
| title | A rare case of hepatic flexure Gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC) |
| title_full | A rare case of hepatic flexure Gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC) |
| title_fullStr | A rare case of hepatic flexure Gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC) |
| title_full_unstemmed | A rare case of hepatic flexure Gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC) |
| title_short | A rare case of hepatic flexure Gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC) |
| title_sort | rare case of hepatic flexure gastroenteropancreatic neuroendocrine carcinoma (gep-nec) |
| url | http://psasir.upm.edu.my/id/eprint/100345/ http://psasir.upm.edu.my/id/eprint/100345/ http://psasir.upm.edu.my/id/eprint/100345/ http://psasir.upm.edu.my/id/eprint/100345/1/A%20rare%20case%20of%20hepatic%20flexure%20Gastroenteropancreatic%20neuroendocrine%20carcinoma%20%28GEP-NEC%29.pdf |