An updated review of type 1 diabetes in Malaysia

The emerging phenomenon of early-onset type 2 diabetes mellitus (T2D) among Malaysians and misclassification of diabetes types may impact the estimates of prevalence and incidence of type 1 diabetes mellitus (T1D). From previous studies, the prevalence of T1D among the major ethnic groups in Malaysi...

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Main Authors: MN, Nurhanani, M, Hasni, G, Ahmad Mahfuz, A, Masita
Format: Article
Published: Kulliyyah Faculty of Medicine, International Islamic University Malaysia 2022
Online Access:http://psasir.upm.edu.my/id/eprint/100304/
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author MN, Nurhanani
M, Hasni
G, Ahmad Mahfuz
A, Masita
author_facet MN, Nurhanani
M, Hasni
G, Ahmad Mahfuz
A, Masita
author_sort MN, Nurhanani
building UPM Institutional Repository
collection Online Access
description The emerging phenomenon of early-onset type 2 diabetes mellitus (T2D) among Malaysians and misclassification of diabetes types may impact the estimates of prevalence and incidence of type 1 diabetes mellitus (T1D). From previous studies, the prevalence of T1D among the major ethnic groups in Malaysia was seen highest among Chinese, followed by Malays and Indians. More than half of the patients had diabetes ketoacidosis (DKA). This corresponded with the overall poor glycaemic control seen. However, the incidence of chronic complications, such as nephropathy, was lower. The prevalence of autoantibodies was reported highest for anti-islet cell antibody (ICA). As part of treatment, most Malaysian children had one or two daily insulin injections. Generally, older patients responded better to insulin therapy and yielded better glycaemic control than younger patients. While significant advances have been made in understanding T1D in the Malaysian population, more research is warranted to improve the clinical assessment and outcome of the disease. The present narrative review aims to summarise the overall status of T1D in Malaysia, which includes epidemiology, clinical presentation, diagnosis, complications, and management.
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spelling upm-1003042024-03-18T04:17:05Z http://psasir.upm.edu.my/id/eprint/100304/ An updated review of type 1 diabetes in Malaysia MN, Nurhanani M, Hasni G, Ahmad Mahfuz A, Masita The emerging phenomenon of early-onset type 2 diabetes mellitus (T2D) among Malaysians and misclassification of diabetes types may impact the estimates of prevalence and incidence of type 1 diabetes mellitus (T1D). From previous studies, the prevalence of T1D among the major ethnic groups in Malaysia was seen highest among Chinese, followed by Malays and Indians. More than half of the patients had diabetes ketoacidosis (DKA). This corresponded with the overall poor glycaemic control seen. However, the incidence of chronic complications, such as nephropathy, was lower. The prevalence of autoantibodies was reported highest for anti-islet cell antibody (ICA). As part of treatment, most Malaysian children had one or two daily insulin injections. Generally, older patients responded better to insulin therapy and yielded better glycaemic control than younger patients. While significant advances have been made in understanding T1D in the Malaysian population, more research is warranted to improve the clinical assessment and outcome of the disease. The present narrative review aims to summarise the overall status of T1D in Malaysia, which includes epidemiology, clinical presentation, diagnosis, complications, and management. Kulliyyah Faculty of Medicine, International Islamic University Malaysia 2022-07 Article PeerReviewed MN, Nurhanani and M, Hasni and G, Ahmad Mahfuz and A, Masita (2022) An updated review of type 1 diabetes in Malaysia. International Medical Journal Malaysia, 21 (3). 15 - 24. ISSN 1823-4631; ESSN: 2735-2285 https://journals.iium.edu.my/kom/index.php/imjm/article/view/2022 10.31436/imjm.v21i3
spellingShingle MN, Nurhanani
M, Hasni
G, Ahmad Mahfuz
A, Masita
An updated review of type 1 diabetes in Malaysia
title An updated review of type 1 diabetes in Malaysia
title_full An updated review of type 1 diabetes in Malaysia
title_fullStr An updated review of type 1 diabetes in Malaysia
title_full_unstemmed An updated review of type 1 diabetes in Malaysia
title_short An updated review of type 1 diabetes in Malaysia
title_sort updated review of type 1 diabetes in malaysia
url http://psasir.upm.edu.my/id/eprint/100304/
http://psasir.upm.edu.my/id/eprint/100304/
http://psasir.upm.edu.my/id/eprint/100304/