Alcohol withdrawal and the associated mood disorders-a review
Recreational use of alcohol is a social norm in many communities worldwide. Alcohol use in moderation brings pleasure and may protect the cardiovascular system. However, excessive alcohol consumption or alcohol abuse are detrimental to one’s health. Three million deaths due to excessive alcohol cons...
| Main Authors: | , , , , , |
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| Format: | Article |
| Published: |
Multidisciplinary Digital Publishing Institute
2022
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| Online Access: | http://psasir.upm.edu.my/id/eprint/100162/ |
| _version_ | 1848863249980719104 |
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| author | Hui, Helena Lin Ngui Siew, Audrey Foong Kow Lai, Sally Chau, Ling Tham Yu, Cheng Ho Ming, Tatt Lee |
| author_facet | Hui, Helena Lin Ngui Siew, Audrey Foong Kow Lai, Sally Chau, Ling Tham Yu, Cheng Ho Ming, Tatt Lee |
| author_sort | Hui, Helena Lin Ngui |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Recreational use of alcohol is a social norm in many communities worldwide. Alcohol use in moderation brings pleasure and may protect the cardiovascular system. However, excessive alcohol consumption or alcohol abuse are detrimental to one’s health. Three million deaths due to excessive alcohol consumption were reported by the World Health Organization. Emerging evidence also revealed the danger of moderate consumption, which includes the increased risk to cancer. Alcohol abuse and periods of withdrawal have been linked to depression and anxiety. Here, we present the effects of alcohol consumption (acute and chronic) on important brain structures—the frontal lobe, the temporal lobe, the limbic system, and the cerebellum. Apart from this, we also present the link between alcohol abuse and withdrawal and mood disorders in this review, thus drawing a link to oxidative stress. In addition, we also discuss the positive impacts of some pharmacotherapies used. Due to the ever-rising demands of life, the cycle between alcohol abuse, withdrawal, and mood disorders may be a never-ending cycle of destruction. Hence, through this review, we hope that we can emphasise the importance and urgency of managing this issue with the appropriate approaches. |
| first_indexed | 2025-11-15T13:29:55Z |
| format | Article |
| id | upm-100162 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T13:29:55Z |
| publishDate | 2022 |
| publisher | Multidisciplinary Digital Publishing Institute |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1001622024-07-18T07:30:54Z http://psasir.upm.edu.my/id/eprint/100162/ Alcohol withdrawal and the associated mood disorders-a review Hui, Helena Lin Ngui Siew, Audrey Foong Kow Lai, Sally Chau, Ling Tham Yu, Cheng Ho Ming, Tatt Lee Recreational use of alcohol is a social norm in many communities worldwide. Alcohol use in moderation brings pleasure and may protect the cardiovascular system. However, excessive alcohol consumption or alcohol abuse are detrimental to one’s health. Three million deaths due to excessive alcohol consumption were reported by the World Health Organization. Emerging evidence also revealed the danger of moderate consumption, which includes the increased risk to cancer. Alcohol abuse and periods of withdrawal have been linked to depression and anxiety. Here, we present the effects of alcohol consumption (acute and chronic) on important brain structures—the frontal lobe, the temporal lobe, the limbic system, and the cerebellum. Apart from this, we also present the link between alcohol abuse and withdrawal and mood disorders in this review, thus drawing a link to oxidative stress. In addition, we also discuss the positive impacts of some pharmacotherapies used. Due to the ever-rising demands of life, the cycle between alcohol abuse, withdrawal, and mood disorders may be a never-ending cycle of destruction. Hence, through this review, we hope that we can emphasise the importance and urgency of managing this issue with the appropriate approaches. Multidisciplinary Digital Publishing Institute 2022-11-29 Article PeerReviewed Hui, Helena Lin Ngui and Siew, Audrey Foong Kow and Lai, Sally and Chau, Ling Tham and Yu, Cheng Ho and Ming, Tatt Lee (2022) Alcohol withdrawal and the associated mood disorders-a review. International Journal of Molecular Sciences, 23 (23). art. no. 14912. pp. 1-32. ISSN 1661-6596; ESSN: 1422-0067 https://www.mdpi.com/1422-0067/23/23/14912 10.3390/ijms232314912 |
| spellingShingle | Hui, Helena Lin Ngui Siew, Audrey Foong Kow Lai, Sally Chau, Ling Tham Yu, Cheng Ho Ming, Tatt Lee Alcohol withdrawal and the associated mood disorders-a review |
| title | Alcohol withdrawal and the associated mood disorders-a review |
| title_full | Alcohol withdrawal and the associated mood disorders-a review |
| title_fullStr | Alcohol withdrawal and the associated mood disorders-a review |
| title_full_unstemmed | Alcohol withdrawal and the associated mood disorders-a review |
| title_short | Alcohol withdrawal and the associated mood disorders-a review |
| title_sort | alcohol withdrawal and the associated mood disorders-a review |
| url | http://psasir.upm.edu.my/id/eprint/100162/ http://psasir.upm.edu.my/id/eprint/100162/ http://psasir.upm.edu.my/id/eprint/100162/ |