Etoposide-induced apoptosis results in chromosome breaks within the AF9 gene: Its implication in chromosome rearrangement in leukaemia

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Etoposide-induced apoptosis results in chromosome breaks within the AF9 gene: Its implication in chromosome rearrangement in leukaemia

Treatment with etoposide (VP-16) has been associated with translocation of the mixed lineage leukaemia (MLL) gene seen in treatment-related acute myeloid leukaemia (t-AML). Among the different partner genes, AF9 is the most common partner gene of MLL. AF9 shares similar structural element with the M...

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Bibliographic Details
Main Authors:	Cynthia Patricia, Nicholas, Sim, S.P
Format:	Article
Published:	Scientific Research Publishing 2012
Subjects:	R Medicine (General)
Online Access:	http://ir.unimas.my/id/eprint/8232/

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