Antibiotics Resistant and Genetic Diversity of Escherichia coli Isolated From Aquaculture Environments

The use of antibiotics in the aquaculture environments poses a risk that resistance to antibiotics will develop in the environmental organisms, in the endogenous bacterial population of farmed species, and in their pathogens. Antibiotic resistance bacteria constitute direct or indirect threat to f...

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Main Author: Nurismi, Ismaili
Format: Final Year Project Report / IMRAD
Language:English
Published: Universiti Malaysia Sarawak, UNIMAS 2013
Subjects:
Online Access:http://ir.unimas.my/id/eprint/7914/
http://ir.unimas.my/id/eprint/7914/4/Nurismi%20Bt%20Ismaili%20ft.pdf
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author Nurismi, Ismaili
author_facet Nurismi, Ismaili
author_sort Nurismi, Ismaili
building UNIMAS Institutional Repository
collection Online Access
description The use of antibiotics in the aquaculture environments poses a risk that resistance to antibiotics will develop in the environmental organisms, in the endogenous bacterial population of farmed species, and in their pathogens. Antibiotic resistance bacteria constitute direct or indirect threat to farmers and the public through potential transfer of resistance to human and animal pathogens. This study was conducted to obtain a preliminary indication of the extent of antibiotic resistance in the aquaculture environments in Sarawak. Escherichia coli were isolated from the fish, water, and the sediment of the aquaculture environments. Antibiotic susceptibility test was conducted to determine the antibiotic resistance patterns of the isolates. DNA profiling of E. coli was conducted to see the diversity of the isolates in the aquaculture environment through RAPD-PCR analysis. Nineteen isolates of E. coli were isolated from the fish, water and sediment. All the isolates show resistant to at least one of the eight antibiotics tested. The highest level of resistance was observed against erythromycin (94.74%) and the lowest was against nalidixic acid (5.26%). The RAPD analysis with primers Gen-1-50-09 and Gen1-50-10 grouped the E. coli isolates in 4 and 3 main groups, respectively. The results of this study suggested that E. coli isolates were genetically diverse and the fish, sediment and water are potential reservoir for antibiotic resistance of E. coli.
first_indexed 2025-11-15T06:20:53Z
format Final Year Project Report / IMRAD
id unimas-7914
institution Universiti Malaysia Sarawak
institution_category Local University
language English
last_indexed 2025-11-15T06:20:53Z
publishDate 2013
publisher Universiti Malaysia Sarawak, UNIMAS
recordtype eprints
repository_type Digital Repository
spelling unimas-79142023-11-13T07:32:57Z http://ir.unimas.my/id/eprint/7914/ Antibiotics Resistant and Genetic Diversity of Escherichia coli Isolated From Aquaculture Environments Nurismi, Ismaili Q Science (General) The use of antibiotics in the aquaculture environments poses a risk that resistance to antibiotics will develop in the environmental organisms, in the endogenous bacterial population of farmed species, and in their pathogens. Antibiotic resistance bacteria constitute direct or indirect threat to farmers and the public through potential transfer of resistance to human and animal pathogens. This study was conducted to obtain a preliminary indication of the extent of antibiotic resistance in the aquaculture environments in Sarawak. Escherichia coli were isolated from the fish, water, and the sediment of the aquaculture environments. Antibiotic susceptibility test was conducted to determine the antibiotic resistance patterns of the isolates. DNA profiling of E. coli was conducted to see the diversity of the isolates in the aquaculture environment through RAPD-PCR analysis. Nineteen isolates of E. coli were isolated from the fish, water and sediment. All the isolates show resistant to at least one of the eight antibiotics tested. The highest level of resistance was observed against erythromycin (94.74%) and the lowest was against nalidixic acid (5.26%). The RAPD analysis with primers Gen-1-50-09 and Gen1-50-10 grouped the E. coli isolates in 4 and 3 main groups, respectively. The results of this study suggested that E. coli isolates were genetically diverse and the fish, sediment and water are potential reservoir for antibiotic resistance of E. coli. Universiti Malaysia Sarawak, UNIMAS 2013 Final Year Project Report / IMRAD NonPeerReviewed text en http://ir.unimas.my/id/eprint/7914/4/Nurismi%20Bt%20Ismaili%20ft.pdf Nurismi, Ismaili (2013) Antibiotics Resistant and Genetic Diversity of Escherichia coli Isolated From Aquaculture Environments. [Final Year Project Report / IMRAD] (Unpublished)
spellingShingle Q Science (General)
Nurismi, Ismaili
Antibiotics Resistant and Genetic Diversity of Escherichia coli Isolated From Aquaculture Environments
title Antibiotics Resistant and Genetic Diversity of Escherichia coli Isolated From Aquaculture Environments
title_full Antibiotics Resistant and Genetic Diversity of Escherichia coli Isolated From Aquaculture Environments
title_fullStr Antibiotics Resistant and Genetic Diversity of Escherichia coli Isolated From Aquaculture Environments
title_full_unstemmed Antibiotics Resistant and Genetic Diversity of Escherichia coli Isolated From Aquaculture Environments
title_short Antibiotics Resistant and Genetic Diversity of Escherichia coli Isolated From Aquaculture Environments
title_sort antibiotics resistant and genetic diversity of escherichia coli isolated from aquaculture environments
topic Q Science (General)
url http://ir.unimas.my/id/eprint/7914/
http://ir.unimas.my/id/eprint/7914/4/Nurismi%20Bt%20Ismaili%20ft.pdf