Screening and isolation of amylolytic fungus and crude enzyme characterization from Sago industrial waste

Five best amylolytic fungus from 15 successful by isolates from sago industrial waste were selected and studied for crude enzyme starch digesting ability, enzyme properties, enzyme production as well as fungal morphological and molecular identification. This study had revealed that Ceratocystis par...

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Main Author: Koh, Seng Fook
Format: Final Year Project Report / IMRAD
Language:English
English
Published: Universiti Malaysia Sarawak, UNIMAS 2007
Subjects:
Online Access:http://ir.unimas.my/id/eprint/7620/
http://ir.unimas.my/id/eprint/7620/1/Koh.pdf
http://ir.unimas.my/id/eprint/7620/4/Koh%20Seng%20Fook%20ft.pdf
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author Koh, Seng Fook
author_facet Koh, Seng Fook
author_sort Koh, Seng Fook
building UNIMAS Institutional Repository
collection Online Access
description Five best amylolytic fungus from 15 successful by isolates from sago industrial waste were selected and studied for crude enzyme starch digesting ability, enzyme properties, enzyme production as well as fungal morphological and molecular identification. This study had revealed that Ceratocystis paradoxa is the best amylolytic fungus from all the isolates. Starch-iodine assay was use to determine the enzyme activity. The kinetic constant (Km), maximum velocity (Vmax) and catalytic constant (kcat) was recorded at 1363.5 mg/ml, 144.9 U/ml, 8.17 mg/ml minutes-1 respectively for Ceratocystis paradoxa. The crude enzyme is thermostable on all assayed temperature where the optimum temperature is 60oC, and maintained high relative activity (80 % and above) in pH 4.0 to 8.0 from studies performed, as well as remaining stable in the presence of metal ions (Cu2+, CO2+, Mn2+, Ca2+, Zn2+, Mg2+, Fe2+) studied. The genetic related study between the 5 isolates via ITS primers and DNA sequencing was also performed. Further study should be emphasizing on the optimization of fungal crude enzyme production, solid state fermentation, cloning of the enzyme expression gene, as well as further molecular studies on the development of expressed sequence tag (EST) and random sequence tags (RSTs) in the future.
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format Final Year Project Report / IMRAD
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institution Universiti Malaysia Sarawak
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language English
English
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publishDate 2007
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spelling unimas-76202023-10-10T02:53:22Z http://ir.unimas.my/id/eprint/7620/ Screening and isolation of amylolytic fungus and crude enzyme characterization from Sago industrial waste Koh, Seng Fook S Agriculture (General) Five best amylolytic fungus from 15 successful by isolates from sago industrial waste were selected and studied for crude enzyme starch digesting ability, enzyme properties, enzyme production as well as fungal morphological and molecular identification. This study had revealed that Ceratocystis paradoxa is the best amylolytic fungus from all the isolates. Starch-iodine assay was use to determine the enzyme activity. The kinetic constant (Km), maximum velocity (Vmax) and catalytic constant (kcat) was recorded at 1363.5 mg/ml, 144.9 U/ml, 8.17 mg/ml minutes-1 respectively for Ceratocystis paradoxa. The crude enzyme is thermostable on all assayed temperature where the optimum temperature is 60oC, and maintained high relative activity (80 % and above) in pH 4.0 to 8.0 from studies performed, as well as remaining stable in the presence of metal ions (Cu2+, CO2+, Mn2+, Ca2+, Zn2+, Mg2+, Fe2+) studied. The genetic related study between the 5 isolates via ITS primers and DNA sequencing was also performed. Further study should be emphasizing on the optimization of fungal crude enzyme production, solid state fermentation, cloning of the enzyme expression gene, as well as further molecular studies on the development of expressed sequence tag (EST) and random sequence tags (RSTs) in the future. Universiti Malaysia Sarawak, UNIMAS 2007 Final Year Project Report / IMRAD NonPeerReviewed text en http://ir.unimas.my/id/eprint/7620/1/Koh.pdf text en http://ir.unimas.my/id/eprint/7620/4/Koh%20Seng%20Fook%20ft.pdf Koh, Seng Fook (2007) Screening and isolation of amylolytic fungus and crude enzyme characterization from Sago industrial waste. [Final Year Project Report / IMRAD] (Unpublished)
spellingShingle S Agriculture (General)
Koh, Seng Fook
Screening and isolation of amylolytic fungus and crude enzyme characterization from Sago industrial waste
title Screening and isolation of amylolytic fungus and crude enzyme characterization from Sago industrial waste
title_full Screening and isolation of amylolytic fungus and crude enzyme characterization from Sago industrial waste
title_fullStr Screening and isolation of amylolytic fungus and crude enzyme characterization from Sago industrial waste
title_full_unstemmed Screening and isolation of amylolytic fungus and crude enzyme characterization from Sago industrial waste
title_short Screening and isolation of amylolytic fungus and crude enzyme characterization from Sago industrial waste
title_sort screening and isolation of amylolytic fungus and crude enzyme characterization from sago industrial waste
topic S Agriculture (General)
url http://ir.unimas.my/id/eprint/7620/
http://ir.unimas.my/id/eprint/7620/1/Koh.pdf
http://ir.unimas.my/id/eprint/7620/4/Koh%20Seng%20Fook%20ft.pdf