The study of the reaction of morpholine with aryl halide and aliphatic halide
This study was aimed to synthesized the morpholine derivatives by the cross coupling reaction between morpholine and an aryl halide. The reaction of morpholine with 4-bromobenzaldhyde and 4-bromoanisole. When morpholine reacted with 4-bromoanisole, the reaction was failed but morpholine reacted w...
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| Format: | Final Year Project Report / IMRAD |
| Language: | English |
| Published: |
Universiti Malaysia Sarawak, UNIMAS
2013
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| Subjects: | |
| Online Access: | http://ir.unimas.my/id/eprint/7619/ http://ir.unimas.my/id/eprint/7619/6/Dorairaaj%20AL%20Sivasubramaniam%20ft.pdf |
| _version_ | 1848836172837552128 |
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| author | Dorairaaj, A/L Sivasubramaniam |
| author_facet | Dorairaaj, A/L Sivasubramaniam |
| author_sort | Dorairaaj, A/L Sivasubramaniam |
| building | UNIMAS Institutional Repository |
| collection | Online Access |
| description | This study was aimed to synthesized the morpholine derivatives by the cross coupling reaction
between morpholine and an aryl halide. The reaction of morpholine with 4-bromobenzaldhyde
and 4-bromoanisole. When morpholine reacted with 4-bromoanisole, the reaction was failed but
morpholine reacted with 4-bromobenzaldehyde produced 4-morpholine-4-yl-benzaldehyde, which
showed that the reaction was successful. The reaction of morpholine with 4-bromobenzaldehyde
was compared in the presence and absence of the copper(I) iodide which act as a catalyst. The
GC result showed that the conversion of the product without catalyst was much more higher than
the reaction with catalyst under the same condition. The side product also was discovered in the
reaction without catalyst, the morpholine actually was attacked to the carbon in the carbonyl
group of 4-bromobenzaldehyde to produce 4-bromobenzoic acid,morpholide. |
| first_indexed | 2025-11-15T06:19:33Z |
| format | Final Year Project Report / IMRAD |
| id | unimas-7619 |
| institution | Universiti Malaysia Sarawak |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T06:19:33Z |
| publishDate | 2013 |
| publisher | Universiti Malaysia Sarawak, UNIMAS |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | unimas-76192023-02-23T07:59:41Z http://ir.unimas.my/id/eprint/7619/ The study of the reaction of morpholine with aryl halide and aliphatic halide Dorairaaj, A/L Sivasubramaniam Q Science (General) QD Chemistry QH301 Biology This study was aimed to synthesized the morpholine derivatives by the cross coupling reaction between morpholine and an aryl halide. The reaction of morpholine with 4-bromobenzaldhyde and 4-bromoanisole. When morpholine reacted with 4-bromoanisole, the reaction was failed but morpholine reacted with 4-bromobenzaldehyde produced 4-morpholine-4-yl-benzaldehyde, which showed that the reaction was successful. The reaction of morpholine with 4-bromobenzaldehyde was compared in the presence and absence of the copper(I) iodide which act as a catalyst. The GC result showed that the conversion of the product without catalyst was much more higher than the reaction with catalyst under the same condition. The side product also was discovered in the reaction without catalyst, the morpholine actually was attacked to the carbon in the carbonyl group of 4-bromobenzaldehyde to produce 4-bromobenzoic acid,morpholide. Universiti Malaysia Sarawak, UNIMAS 2013 Final Year Project Report / IMRAD NonPeerReviewed text en http://ir.unimas.my/id/eprint/7619/6/Dorairaaj%20AL%20Sivasubramaniam%20ft.pdf Dorairaaj, A/L Sivasubramaniam (2013) The study of the reaction of morpholine with aryl halide and aliphatic halide. [Final Year Project Report / IMRAD] (Unpublished) |
| spellingShingle | Q Science (General) QD Chemistry QH301 Biology Dorairaaj, A/L Sivasubramaniam The study of the reaction of morpholine with aryl halide and aliphatic halide |
| title | The study of the reaction of morpholine with aryl halide and aliphatic halide |
| title_full | The study of the reaction of morpholine with aryl halide and aliphatic halide |
| title_fullStr | The study of the reaction of morpholine with aryl halide and aliphatic halide |
| title_full_unstemmed | The study of the reaction of morpholine with aryl halide and aliphatic halide |
| title_short | The study of the reaction of morpholine with aryl halide and aliphatic halide |
| title_sort | study of the reaction of morpholine with aryl halide and aliphatic halide |
| topic | Q Science (General) QD Chemistry QH301 Biology |
| url | http://ir.unimas.my/id/eprint/7619/ http://ir.unimas.my/id/eprint/7619/6/Dorairaaj%20AL%20Sivasubramaniam%20ft.pdf |