Isolation of high quality genomic dna from dryobnanalops beccarii dyer tissues rich in camphor

The isolation of high-quality intact genomic DNA is obviously difficult in a variety of plant species due to the presence of high levels of polysaccharides, polyphenolics and other secondary metabolites. These contaminants will co-precipitate with DNA during DNA isolation and purification processes,...

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Main Author: Liew, Kit Siong
Format: Final Year Project Report / IMRAD
Language:English
Published: Universiti Malaysia Sarawak (UNIMAS) 2007
Subjects:
Online Access:http://ir.unimas.my/id/eprint/7609/
http://ir.unimas.my/id/eprint/7609/3/LIEW%20KIT%20SIONG.pdf
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author Liew, Kit Siong
author_facet Liew, Kit Siong
author_sort Liew, Kit Siong
building UNIMAS Institutional Repository
collection Online Access
description The isolation of high-quality intact genomic DNA is obviously difficult in a variety of plant species due to the presence of high levels of polysaccharides, polyphenolics and other secondary metabolites. These contaminants will co-precipitate with DNA during DNA isolation and purification processes, and therefore, resulting in a brownish DNA pellet that is unsuitable for downstream applications. Most plant genomic DNA isolation protocols for various plant tissues have been established; however these protocols are inefficient in yielding high-quality amplifiable genomic DNA especially from camphor containing timber species, Drynobanalops beccarii Dyer. In this project, the total genomic DNA of Drynobanalops beccarii was successfully isolated using a re-optimized CTAB method based on the Murray & Thompson (1980) and Doyle & Doyle (1990). The modifications include: 1) using 1% =-mercaptoethanol and 2% PVP (Mr 40000) in the extraction buffer, 2) sample incubation time, 40 minutes at 65°C; and 3) DNA precipitation at room temperature (25°C). The isolated DNA pellet was in transparent colour and yielded amplifiable genomic DNA for RAPD-PCR.
first_indexed 2025-11-15T06:19:30Z
format Final Year Project Report / IMRAD
id unimas-7609
institution Universiti Malaysia Sarawak
institution_category Local University
language English
last_indexed 2025-11-15T06:19:30Z
publishDate 2007
publisher Universiti Malaysia Sarawak (UNIMAS)
recordtype eprints
repository_type Digital Repository
spelling unimas-76092024-01-02T07:33:30Z http://ir.unimas.my/id/eprint/7609/ Isolation of high quality genomic dna from dryobnanalops beccarii dyer tissues rich in camphor Liew, Kit Siong SB Plant culture The isolation of high-quality intact genomic DNA is obviously difficult in a variety of plant species due to the presence of high levels of polysaccharides, polyphenolics and other secondary metabolites. These contaminants will co-precipitate with DNA during DNA isolation and purification processes, and therefore, resulting in a brownish DNA pellet that is unsuitable for downstream applications. Most plant genomic DNA isolation protocols for various plant tissues have been established; however these protocols are inefficient in yielding high-quality amplifiable genomic DNA especially from camphor containing timber species, Drynobanalops beccarii Dyer. In this project, the total genomic DNA of Drynobanalops beccarii was successfully isolated using a re-optimized CTAB method based on the Murray & Thompson (1980) and Doyle & Doyle (1990). The modifications include: 1) using 1% =-mercaptoethanol and 2% PVP (Mr 40000) in the extraction buffer, 2) sample incubation time, 40 minutes at 65°C; and 3) DNA precipitation at room temperature (25°C). The isolated DNA pellet was in transparent colour and yielded amplifiable genomic DNA for RAPD-PCR. Universiti Malaysia Sarawak (UNIMAS) 2007 Final Year Project Report / IMRAD NonPeerReviewed text en http://ir.unimas.my/id/eprint/7609/3/LIEW%20KIT%20SIONG.pdf Liew, Kit Siong (2007) Isolation of high quality genomic dna from dryobnanalops beccarii dyer tissues rich in camphor. [Final Year Project Report / IMRAD] (Unpublished)
spellingShingle SB Plant culture
Liew, Kit Siong
Isolation of high quality genomic dna from dryobnanalops beccarii dyer tissues rich in camphor
title Isolation of high quality genomic dna from dryobnanalops beccarii dyer tissues rich in camphor
title_full Isolation of high quality genomic dna from dryobnanalops beccarii dyer tissues rich in camphor
title_fullStr Isolation of high quality genomic dna from dryobnanalops beccarii dyer tissues rich in camphor
title_full_unstemmed Isolation of high quality genomic dna from dryobnanalops beccarii dyer tissues rich in camphor
title_short Isolation of high quality genomic dna from dryobnanalops beccarii dyer tissues rich in camphor
title_sort isolation of high quality genomic dna from dryobnanalops beccarii dyer tissues rich in camphor
topic SB Plant culture
url http://ir.unimas.my/id/eprint/7609/
http://ir.unimas.my/id/eprint/7609/3/LIEW%20KIT%20SIONG.pdf