Synthesis, spectral characterization and cytotoxic activity of 3D-transition metal complexes with O-vanillin benzoylhydrazone ligand
Six new Mn(II), Fe(II), Co(II), Ni(II), Cu(II) and Zn(II) complexes (2-7) of o-vanillin benzoylhydrazone ligand (1) have been synthesized and characterized. The ligand (1) and its 3dmetal complexes (2-7) were characterized by elemental analysis, molar conductivity, UVVisible, FT-IR and 1H NMR spe...
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| Format: | Final Year Project Report / IMRAD |
| Language: | English |
| Published: |
Universiti Malaysia Sarawak, UNIMAS
2012
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| Subjects: | |
| Online Access: | http://ir.unimas.my/id/eprint/7444/ http://ir.unimas.my/id/eprint/7444/4/Husna%20Sarfina.pdf |
| _version_ | 1848836131954622464 |
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| author | Husna Sarfina, Bt Husain |
| author_facet | Husna Sarfina, Bt Husain |
| author_sort | Husna Sarfina, Bt Husain |
| building | UNIMAS Institutional Repository |
| collection | Online Access |
| description | Six new Mn(II), Fe(II), Co(II), Ni(II), Cu(II) and Zn(II) complexes (2-7) of o-vanillin
benzoylhydrazone ligand (1) have been synthesized and characterized. The ligand (1) and its 3dmetal
complexes (2-7) were characterized by elemental analysis, molar conductivity, UVVisible,
FT-IR and 1H NMR spectroscopic studies. The spectroscopic data of the complexes (2-
7) suggested that the ligand (1) is acted as a dinegative tridentate chelating system and is
coordinated to central metal(II) atom through phenoxide-O, atomethine-N and carboxylate-O
atoms. Four coordinated molecular structure has been proposed for the synthesized 3d-transition
metal complexes. The ligand (1) and its metal complexes (2-7) have also been tested for their
cytotoxicity and found to be less active against Artemia salina. |
| first_indexed | 2025-11-15T06:18:54Z |
| format | Final Year Project Report / IMRAD |
| id | unimas-7444 |
| institution | Universiti Malaysia Sarawak |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T06:18:54Z |
| publishDate | 2012 |
| publisher | Universiti Malaysia Sarawak, UNIMAS |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | unimas-74442023-10-27T02:35:17Z http://ir.unimas.my/id/eprint/7444/ Synthesis, spectral characterization and cytotoxic activity of 3D-transition metal complexes with O-vanillin benzoylhydrazone ligand Husna Sarfina, Bt Husain Q Science (General) QD Chemistry Six new Mn(II), Fe(II), Co(II), Ni(II), Cu(II) and Zn(II) complexes (2-7) of o-vanillin benzoylhydrazone ligand (1) have been synthesized and characterized. The ligand (1) and its 3dmetal complexes (2-7) were characterized by elemental analysis, molar conductivity, UVVisible, FT-IR and 1H NMR spectroscopic studies. The spectroscopic data of the complexes (2- 7) suggested that the ligand (1) is acted as a dinegative tridentate chelating system and is coordinated to central metal(II) atom through phenoxide-O, atomethine-N and carboxylate-O atoms. Four coordinated molecular structure has been proposed for the synthesized 3d-transition metal complexes. The ligand (1) and its metal complexes (2-7) have also been tested for their cytotoxicity and found to be less active against Artemia salina. Universiti Malaysia Sarawak, UNIMAS 2012 Final Year Project Report / IMRAD NonPeerReviewed text en http://ir.unimas.my/id/eprint/7444/4/Husna%20Sarfina.pdf Husna Sarfina, Bt Husain (2012) Synthesis, spectral characterization and cytotoxic activity of 3D-transition metal complexes with O-vanillin benzoylhydrazone ligand. [Final Year Project Report / IMRAD] (Unpublished) |
| spellingShingle | Q Science (General) QD Chemistry Husna Sarfina, Bt Husain Synthesis, spectral characterization and cytotoxic activity of 3D-transition metal complexes with O-vanillin benzoylhydrazone ligand |
| title | Synthesis, spectral characterization and cytotoxic activity of 3D-transition metal complexes with O-vanillin benzoylhydrazone ligand |
| title_full | Synthesis, spectral characterization and cytotoxic activity of 3D-transition metal complexes with O-vanillin benzoylhydrazone ligand |
| title_fullStr | Synthesis, spectral characterization and cytotoxic activity of 3D-transition metal complexes with O-vanillin benzoylhydrazone ligand |
| title_full_unstemmed | Synthesis, spectral characterization and cytotoxic activity of 3D-transition metal complexes with O-vanillin benzoylhydrazone ligand |
| title_short | Synthesis, spectral characterization and cytotoxic activity of 3D-transition metal complexes with O-vanillin benzoylhydrazone ligand |
| title_sort | synthesis, spectral characterization and cytotoxic activity of 3d-transition metal complexes with o-vanillin benzoylhydrazone ligand |
| topic | Q Science (General) QD Chemistry |
| url | http://ir.unimas.my/id/eprint/7444/ http://ir.unimas.my/id/eprint/7444/4/Husna%20Sarfina.pdf |