Synthesis and spectroscopic characterization of cholesteryl hydrogen phthalate and its derivatives

The synthesis and spectroscopic characterization of cholesteryl hydrogen phthalate and its derivatives (methyl-, ethyl-, isopropyl- , di- and stigmasteryl-) are reported in this paper. Cholesterol as well as phthalic anhydride have been used as the starting materials in preparing cholesteryl hydroge...

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Main Authors: PF, Ng, TW, Sam, MC, Feng, CB, Yeoh, MG, Tay
Format: Article
Published: India National Science Academy , India. 2004
Subjects:
Online Access:http://ir.unimas.my/id/eprint/7408/
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author PF, Ng
TW, Sam
MC, Feng
CB, Yeoh
MG, Tay
author_facet PF, Ng
TW, Sam
MC, Feng
CB, Yeoh
MG, Tay
author_sort PF, Ng
building UNIMAS Institutional Repository
collection Online Access
description The synthesis and spectroscopic characterization of cholesteryl hydrogen phthalate and its derivatives (methyl-, ethyl-, isopropyl- , di- and stigmasteryl-) are reported in this paper. Cholesterol as well as phthalic anhydride have been used as the starting materials in preparing cholesteryl hydrogen phthalate. This compound was followed by the esterification of half ester by refluxing with methanol , ethanol and isopropanol, respectively. In preparation of dicholesteryl phthalate and stigmasteryl cholesteryl phthalate, esterification with direct heat method has been tried. All the compounds are characterized by NMR (1H and 13C) and FTIR spectra.
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institution Universiti Malaysia Sarawak
institution_category Local University
last_indexed 2025-11-15T06:18:44Z
publishDate 2004
publisher India National Science Academy , India.
recordtype eprints
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spelling unimas-74082015-05-12T08:12:52Z http://ir.unimas.my/id/eprint/7408/ Synthesis and spectroscopic characterization of cholesteryl hydrogen phthalate and its derivatives PF, Ng TW, Sam MC, Feng CB, Yeoh MG, Tay QC Physics QD Chemistry The synthesis and spectroscopic characterization of cholesteryl hydrogen phthalate and its derivatives (methyl-, ethyl-, isopropyl- , di- and stigmasteryl-) are reported in this paper. Cholesterol as well as phthalic anhydride have been used as the starting materials in preparing cholesteryl hydrogen phthalate. This compound was followed by the esterification of half ester by refluxing with methanol , ethanol and isopropanol, respectively. In preparation of dicholesteryl phthalate and stigmasteryl cholesteryl phthalate, esterification with direct heat method has been tried. All the compounds are characterized by NMR (1H and 13C) and FTIR spectra. India National Science Academy , India. 2004 Article PeerReviewed PF, Ng and TW, Sam and MC, Feng and CB, Yeoh and MG, Tay (2004) Synthesis and spectroscopic characterization of cholesteryl hydrogen phthalate and its derivatives. Indian journal of chemistry. Sect. B: Organic chemistry, including medical chemistry, 43 (9). pp. 1939-1943. ISSN 0975-0983 http://nopr.niscair.res.in/handle/123456789/21325
spellingShingle QC Physics
QD Chemistry
PF, Ng
TW, Sam
MC, Feng
CB, Yeoh
MG, Tay
Synthesis and spectroscopic characterization of cholesteryl hydrogen phthalate and its derivatives
title Synthesis and spectroscopic characterization of cholesteryl hydrogen phthalate and its derivatives
title_full Synthesis and spectroscopic characterization of cholesteryl hydrogen phthalate and its derivatives
title_fullStr Synthesis and spectroscopic characterization of cholesteryl hydrogen phthalate and its derivatives
title_full_unstemmed Synthesis and spectroscopic characterization of cholesteryl hydrogen phthalate and its derivatives
title_short Synthesis and spectroscopic characterization of cholesteryl hydrogen phthalate and its derivatives
title_sort synthesis and spectroscopic characterization of cholesteryl hydrogen phthalate and its derivatives
topic QC Physics
QD Chemistry
url http://ir.unimas.my/id/eprint/7408/
http://ir.unimas.my/id/eprint/7408/