Chemical studies on biologically active natural product from medicinal plants in Sabah

ABSTRACT. A concerted e_} j" ort has been undertaken to study the abundant hioiogicai resources of5'abah especiaiiy those with medicinal vaiues in order to discover new drugs for the treatment of diseases. Important source of new drug are those derived from naturai products, and among natu...

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Main Author: Fasihuddin b., Ahmad
Format: Article
Published: Borneo Science 2000
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Online Access:http://ir.unimas.my/id/eprint/7359/
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author Fasihuddin b., Ahmad
author_facet Fasihuddin b., Ahmad
author_sort Fasihuddin b., Ahmad
building UNIMAS Institutional Repository
collection Online Access
description ABSTRACT. A concerted e_} j" ort has been undertaken to study the abundant hioiogicai resources of5'abah especiaiiy those with medicinal vaiues in order to discover new drugs for the treatment of diseases. Important source of new drug are those derived from naturai products, and among naturaiiy derived products, piants have proven to be a major source for new pharmacoiogicai agents especiaiiy in treating cancer and AIDS. More then ti-!'}'fl medicinal piants used by various ethnic groups have been documented. Phytochemical studies on some of the selected plants showed interesting results. Studies on Goniothalamus boorneensis resulted in the isolation of goniothalenol, goniotriol, goniothalamin, goniobutenolide A, goniofufurone goniothalesdiol, goniothalactam and aristolactam A-III, all with interesting biological activity and studies on G, velutinus resulted in the isolation of aristololactam-BII abd velutinam with cytotoxic activity. Alstophyline and vilastonine have been isolated from Alstonia scholaris while studies on Litsea pallidifolia resulted in isolation of oxycanthine and obaberine all with antimalarial activity. Users and phytochemical information on some of the plants will be discussed.
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spelling unimas-73592015-05-12T02:05:51Z http://ir.unimas.my/id/eprint/7359/ Chemical studies on biologically active natural product from medicinal plants in Sabah Fasihuddin b., Ahmad QD Chemistry ABSTRACT. A concerted e_} j" ort has been undertaken to study the abundant hioiogicai resources of5'abah especiaiiy those with medicinal vaiues in order to discover new drugs for the treatment of diseases. Important source of new drug are those derived from naturai products, and among naturaiiy derived products, piants have proven to be a major source for new pharmacoiogicai agents especiaiiy in treating cancer and AIDS. More then ti-!'}'fl medicinal piants used by various ethnic groups have been documented. Phytochemical studies on some of the selected plants showed interesting results. Studies on Goniothalamus boorneensis resulted in the isolation of goniothalenol, goniotriol, goniothalamin, goniobutenolide A, goniofufurone goniothalesdiol, goniothalactam and aristolactam A-III, all with interesting biological activity and studies on G, velutinus resulted in the isolation of aristololactam-BII abd velutinam with cytotoxic activity. Alstophyline and vilastonine have been isolated from Alstonia scholaris while studies on Litsea pallidifolia resulted in isolation of oxycanthine and obaberine all with antimalarial activity. Users and phytochemical information on some of the plants will be discussed. Borneo Science 2000 Article PeerReviewed Fasihuddin b., Ahmad (2000) Chemical studies on biologically active natural product from medicinal plants in Sabah. Borneo Science, 7. pp. 55-62. ISSN 2231-9085, 1394-4339 http://borneoscience.ums.edu.my/wp-content/uploads/2011/08/6.-Chemical-Studies-On-Biologically-active-natural-product-from-medicinal-plants-in-Sabah.pdf
spellingShingle QD Chemistry
Fasihuddin b., Ahmad
Chemical studies on biologically active natural product from medicinal plants in Sabah
title Chemical studies on biologically active natural product from medicinal plants in Sabah
title_full Chemical studies on biologically active natural product from medicinal plants in Sabah
title_fullStr Chemical studies on biologically active natural product from medicinal plants in Sabah
title_full_unstemmed Chemical studies on biologically active natural product from medicinal plants in Sabah
title_short Chemical studies on biologically active natural product from medicinal plants in Sabah
title_sort chemical studies on biologically active natural product from medicinal plants in sabah
topic QD Chemistry
url http://ir.unimas.my/id/eprint/7359/
http://ir.unimas.my/id/eprint/7359/