Synthesis, characterization, and antibacterial activity of organotin (IV) complexes with 2-hydroxyacetophenone thiocarbohydrazone

Six new organotin(IV) complexes were synthesized by direct reaction of RSnCl3 (R = Me, Bu and Ph) or R2SnCl2 (R = Me, Bu and Ph) and 2-hydroxyacetophenone thiocarbohydrazone [H2APTC] under purified nitrogen in the presence of base in 1 : 2 : 1 molar ratio (metal: base: ligand). Complexes 2–7 have be...

Full description

Bibliographic Details
Main Authors: Fasihuddin Badruddin, Ahmad, Dayang NA, Chee, Md. Abu, Affan, MR, Asarud, Norrihan, Sam, MA, Salam, Ahmad, Ismail, SH, Tan
Format: Article
Published: Taylor & Francis Group 2011
Subjects:
Online Access:http://ir.unimas.my/id/eprint/7327/
_version_ 1848836104948547584
author Fasihuddin Badruddin, Ahmad
Dayang NA, Chee
Md. Abu, Affan
MR, Asarud
Norrihan, Sam
MA, Salam
Ahmad, Ismail
SH, Tan
author_facet Fasihuddin Badruddin, Ahmad
Dayang NA, Chee
Md. Abu, Affan
MR, Asarud
Norrihan, Sam
MA, Salam
Ahmad, Ismail
SH, Tan
author_sort Fasihuddin Badruddin, Ahmad
building UNIMAS Institutional Repository
collection Online Access
description Six new organotin(IV) complexes were synthesized by direct reaction of RSnCl3 (R = Me, Bu and Ph) or R2SnCl2 (R = Me, Bu and Ph) and 2-hydroxyacetophenone thiocarbohydrazone [H2APTC] under purified nitrogen in the presence of base in 1 : 2 : 1 molar ratio (metal: base: ligand). Complexes 2–7 have been characterized by elemental analyses, molar conductivity, UV-Visible, IR and 1H NMR spectral studies. Complexes 2–7 are non-electrolytes. The molecular structure of [Me2Sn(APTC)] · (C2H5OH) (5) has been determined by X-ray diffraction analysis. The thiocarbohydrazone ligand (1) and 2–7 have been tested for antibacterial activity against Escherichia coli, Staphylococcus aureus, Salmonella typhi and Enterococci aeruginosa.
first_indexed 2025-11-15T06:18:28Z
format Article
id unimas-7327
institution Universiti Malaysia Sarawak
institution_category Local University
last_indexed 2025-11-15T06:18:28Z
publishDate 2011
publisher Taylor & Francis Group
recordtype eprints
repository_type Digital Repository
spelling unimas-73272016-04-20T00:38:19Z http://ir.unimas.my/id/eprint/7327/ Synthesis, characterization, and antibacterial activity of organotin (IV) complexes with 2-hydroxyacetophenone thiocarbohydrazone Fasihuddin Badruddin, Ahmad Dayang NA, Chee Md. Abu, Affan MR, Asarud Norrihan, Sam MA, Salam Ahmad, Ismail SH, Tan QD Chemistry Six new organotin(IV) complexes were synthesized by direct reaction of RSnCl3 (R = Me, Bu and Ph) or R2SnCl2 (R = Me, Bu and Ph) and 2-hydroxyacetophenone thiocarbohydrazone [H2APTC] under purified nitrogen in the presence of base in 1 : 2 : 1 molar ratio (metal: base: ligand). Complexes 2–7 have been characterized by elemental analyses, molar conductivity, UV-Visible, IR and 1H NMR spectral studies. Complexes 2–7 are non-electrolytes. The molecular structure of [Me2Sn(APTC)] · (C2H5OH) (5) has been determined by X-ray diffraction analysis. The thiocarbohydrazone ligand (1) and 2–7 have been tested for antibacterial activity against Escherichia coli, Staphylococcus aureus, Salmonella typhi and Enterococci aeruginosa. Taylor & Francis Group 2011 Article PeerReviewed Fasihuddin Badruddin, Ahmad and Dayang NA, Chee and Md. Abu, Affan and MR, Asarud and Norrihan, Sam and MA, Salam and Ahmad, Ismail and SH, Tan (2011) Synthesis, characterization, and antibacterial activity of organotin (IV) complexes with 2-hydroxyacetophenone thiocarbohydrazone. Journal of Coordination Chemistry, 64 (23). 4191 -4200. ISSN 0095-8972 http://www.tandfonline.com/doi/abs/10.1080/00958972.2011.631532# DOI:10.1080/00958972.2011.631532
spellingShingle QD Chemistry
Fasihuddin Badruddin, Ahmad
Dayang NA, Chee
Md. Abu, Affan
MR, Asarud
Norrihan, Sam
MA, Salam
Ahmad, Ismail
SH, Tan
Synthesis, characterization, and antibacterial activity of organotin (IV) complexes with 2-hydroxyacetophenone thiocarbohydrazone
title Synthesis, characterization, and antibacterial activity of organotin (IV) complexes with 2-hydroxyacetophenone thiocarbohydrazone
title_full Synthesis, characterization, and antibacterial activity of organotin (IV) complexes with 2-hydroxyacetophenone thiocarbohydrazone
title_fullStr Synthesis, characterization, and antibacterial activity of organotin (IV) complexes with 2-hydroxyacetophenone thiocarbohydrazone
title_full_unstemmed Synthesis, characterization, and antibacterial activity of organotin (IV) complexes with 2-hydroxyacetophenone thiocarbohydrazone
title_short Synthesis, characterization, and antibacterial activity of organotin (IV) complexes with 2-hydroxyacetophenone thiocarbohydrazone
title_sort synthesis, characterization, and antibacterial activity of organotin (iv) complexes with 2-hydroxyacetophenone thiocarbohydrazone
topic QD Chemistry
url http://ir.unimas.my/id/eprint/7327/
http://ir.unimas.my/id/eprint/7327/
http://ir.unimas.my/id/eprint/7327/