Improving the diagnosis management and outcomes of children with pneumonia where are the gaps

Pneumonia is the greatest contributor to childhood mortality and morbidity in resource poor regions, while in high-income countries it is one of the most common reasons for clinic attendance and hospitalization in this age group. Furthermore, pneumonia in children increases the risk of developing ch...

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Main Authors: Chang, Anne B, Ooi, Mong H, David, Perera
Format: Article
Language:English
Published: Frontiers In Pediatrics 2013
Subjects:
Online Access:http://ir.unimas.my/id/eprint/6319/
http://ir.unimas.my/id/eprint/6319/1/Chang%20Anne%20B.pdf
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author Chang, Anne B
Ooi, Mong H
David, Perera
author_facet Chang, Anne B
Ooi, Mong H
David, Perera
author_sort Chang, Anne B
building UNIMAS Institutional Repository
collection Online Access
description Pneumonia is the greatest contributor to childhood mortality and morbidity in resource poor regions, while in high-income countries it is one of the most common reasons for clinic attendance and hospitalization in this age group. Furthermore, pneumonia in children increases the risk of developing chronic pulmonary disorders in later adult life. While substantial advances in managing childhood pneumonia have been made, many issues remain, some of which are highlighted in this perspective. Multiple studies are required as many factors that influence outcomes, such as etiology, patient characteristics, and prevention strategies can vary between and within countries and regions. Also, outside of vaccine studies, most randomized controlled trials (RCTs) on pneumonia have been based in resource-poor countries where the primary aim is usually prevention of mortality. Few RCTs have focused on medium to long-term outcomes or prevention. We propose different tiers of primary outcomes, where in resource-rich countries medium to long-term sequelae should also be included and not just the length of hospitalization and readmission rates.
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spelling unimas-63192021-06-30T13:45:34Z http://ir.unimas.my/id/eprint/6319/ Improving the diagnosis management and outcomes of children with pneumonia where are the gaps Chang, Anne B Ooi, Mong H David, Perera Q Science (General) RJ Pediatrics Pneumonia is the greatest contributor to childhood mortality and morbidity in resource poor regions, while in high-income countries it is one of the most common reasons for clinic attendance and hospitalization in this age group. Furthermore, pneumonia in children increases the risk of developing chronic pulmonary disorders in later adult life. While substantial advances in managing childhood pneumonia have been made, many issues remain, some of which are highlighted in this perspective. Multiple studies are required as many factors that influence outcomes, such as etiology, patient characteristics, and prevention strategies can vary between and within countries and regions. Also, outside of vaccine studies, most randomized controlled trials (RCTs) on pneumonia have been based in resource-poor countries where the primary aim is usually prevention of mortality. Few RCTs have focused on medium to long-term outcomes or prevention. We propose different tiers of primary outcomes, where in resource-rich countries medium to long-term sequelae should also be included and not just the length of hospitalization and readmission rates. Frontiers In Pediatrics 2013 Article PeerReviewed text en http://ir.unimas.my/id/eprint/6319/1/Chang%20Anne%20B.pdf Chang, Anne B and Ooi, Mong H and David, Perera (2013) Improving the diagnosis management and outcomes of children with pneumonia where are the gaps. Frontiers in Pediatrics, 1. ISSN 296-4185 doi: 10.3389/fped.2013.00029
spellingShingle Q Science (General)
RJ Pediatrics
Chang, Anne B
Ooi, Mong H
David, Perera
Improving the diagnosis management and outcomes of children with pneumonia where are the gaps
title Improving the diagnosis management and outcomes of children with pneumonia where are the gaps
title_full Improving the diagnosis management and outcomes of children with pneumonia where are the gaps
title_fullStr Improving the diagnosis management and outcomes of children with pneumonia where are the gaps
title_full_unstemmed Improving the diagnosis management and outcomes of children with pneumonia where are the gaps
title_short Improving the diagnosis management and outcomes of children with pneumonia where are the gaps
title_sort improving the diagnosis management and outcomes of children with pneumonia where are the gaps
topic Q Science (General)
RJ Pediatrics
url http://ir.unimas.my/id/eprint/6319/
http://ir.unimas.my/id/eprint/6319/
http://ir.unimas.my/id/eprint/6319/1/Chang%20Anne%20B.pdf