Synthesis, characterization and antibacterial activity of cu(II) and ni(II) complexes of 3,4,5-trimethoxybenzoyl thiourea ligands
In this study, Cu(II) and Ni(II) complexes of thiourea ligands have been synthesized. The synthesized thiourea ligands were different according to the types of amino acids used which are glycine and phenylalanine. The thiourea ligands and their complexes were characterized using FTIR, UV/Visible,...
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| Format: | Final Year Project Report / IMRAD |
| Language: | English |
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Universiti Malaysia Sarawak, UNIMAS
2012
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| Online Access: | http://ir.unimas.my/id/eprint/6270/ http://ir.unimas.my/id/eprint/6270/4/Norsyafikah%20Asyilla%20Binti%20Nordin%20ft.pdf |
| _version_ | 1848835880153776128 |
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| author | Norsyafikah Asyilla, Binti Nordin |
| author_facet | Norsyafikah Asyilla, Binti Nordin |
| author_sort | Norsyafikah Asyilla, Binti Nordin |
| building | UNIMAS Institutional Repository |
| collection | Online Access |
| description | In this study, Cu(II) and Ni(II) complexes of thiourea ligands have been synthesized. The synthesized thiourea
ligands were different according to the types of amino acids used which are glycine and phenylalanine. The
thiourea ligands and their complexes were characterized using FTIR, UV/Visible, 1H and 13C NMR spectroscopic
methods, CHN microelemental analysis, molar conductivity and melting points. The FTIR stretching vibrations of the complexes showed significant shift compared to the stretching vibrations for the ligands. The n→π*
transition were shown for the ligands and π →π* transition were observed for the complexes. For 1H and 13CNMR, the spectra of the complexes were shifted from the spectra of the ligands. The proposed structures for the complexes were square planar and the ligands were coordinated to the metals through the carboxylate group.
Complex (3) showed significant activity towards the growth of E. coli with the MIC value of 92.5 ppm. |
| first_indexed | 2025-11-15T06:14:54Z |
| format | Final Year Project Report / IMRAD |
| id | unimas-6270 |
| institution | Universiti Malaysia Sarawak |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T06:14:54Z |
| publishDate | 2012 |
| publisher | Universiti Malaysia Sarawak, UNIMAS |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | unimas-62702023-11-20T07:58:23Z http://ir.unimas.my/id/eprint/6270/ Synthesis, characterization and antibacterial activity of cu(II) and ni(II) complexes of 3,4,5-trimethoxybenzoyl thiourea ligands Norsyafikah Asyilla, Binti Nordin Q Science (General) QH301 Biology RA Public aspects of medicine In this study, Cu(II) and Ni(II) complexes of thiourea ligands have been synthesized. The synthesized thiourea ligands were different according to the types of amino acids used which are glycine and phenylalanine. The thiourea ligands and their complexes were characterized using FTIR, UV/Visible, 1H and 13C NMR spectroscopic methods, CHN microelemental analysis, molar conductivity and melting points. The FTIR stretching vibrations of the complexes showed significant shift compared to the stretching vibrations for the ligands. The n→π* transition were shown for the ligands and π →π* transition were observed for the complexes. For 1H and 13CNMR, the spectra of the complexes were shifted from the spectra of the ligands. The proposed structures for the complexes were square planar and the ligands were coordinated to the metals through the carboxylate group. Complex (3) showed significant activity towards the growth of E. coli with the MIC value of 92.5 ppm. Universiti Malaysia Sarawak, UNIMAS 2012 Final Year Project Report / IMRAD NonPeerReviewed text en http://ir.unimas.my/id/eprint/6270/4/Norsyafikah%20Asyilla%20Binti%20Nordin%20ft.pdf Norsyafikah Asyilla, Binti Nordin (2012) Synthesis, characterization and antibacterial activity of cu(II) and ni(II) complexes of 3,4,5-trimethoxybenzoyl thiourea ligands. [Final Year Project Report / IMRAD] (Unpublished) |
| spellingShingle | Q Science (General) QH301 Biology RA Public aspects of medicine Norsyafikah Asyilla, Binti Nordin Synthesis, characterization and antibacterial activity of cu(II) and ni(II) complexes of 3,4,5-trimethoxybenzoyl thiourea ligands |
| title | Synthesis, characterization and antibacterial activity of cu(II) and ni(II) complexes of 3,4,5-trimethoxybenzoyl thiourea ligands |
| title_full | Synthesis, characterization and antibacterial activity of cu(II) and ni(II) complexes of 3,4,5-trimethoxybenzoyl thiourea ligands |
| title_fullStr | Synthesis, characterization and antibacterial activity of cu(II) and ni(II) complexes of 3,4,5-trimethoxybenzoyl thiourea ligands |
| title_full_unstemmed | Synthesis, characterization and antibacterial activity of cu(II) and ni(II) complexes of 3,4,5-trimethoxybenzoyl thiourea ligands |
| title_short | Synthesis, characterization and antibacterial activity of cu(II) and ni(II) complexes of 3,4,5-trimethoxybenzoyl thiourea ligands |
| title_sort | synthesis, characterization and antibacterial activity of cu(ii) and ni(ii) complexes of 3,4,5-trimethoxybenzoyl thiourea ligands |
| topic | Q Science (General) QH301 Biology RA Public aspects of medicine |
| url | http://ir.unimas.my/id/eprint/6270/ http://ir.unimas.my/id/eprint/6270/4/Norsyafikah%20Asyilla%20Binti%20Nordin%20ft.pdf |