Gc-Ms Analysis Of Phytochemical Constituents In Leaf Extracts Of Neolamarckia Cadamba (Rubiaceae) From Malaysia

Neolamarckia cadamba is one of the medicinal plants used in the treatment of various diseases traditionally. This study was conducted to identify the phytochemical constituents of N. cadamba leaf extracts using gas chromatography mass spectrometry (GC-MS). Solvents with increasing polarities viz. he...

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Main Authors: Mohamed, Zaky Zayed, Fasihuddin Badruddin, Ahmad, Wei-Seng, Ho, Shek-Ling, Pang
Format: Article
Language:English
Published: Innovare Academic Sciences 2014
Subjects:
Online Access:http://ir.unimas.my/id/eprint/5586/
http://ir.unimas.my/id/eprint/5586/1/GC-MS.pdf
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author Mohamed, Zaky Zayed
Fasihuddin Badruddin, Ahmad
Wei-Seng, Ho
Shek-Ling, Pang
author_facet Mohamed, Zaky Zayed
Fasihuddin Badruddin, Ahmad
Wei-Seng, Ho
Shek-Ling, Pang
author_sort Mohamed, Zaky Zayed
building UNIMAS Institutional Repository
collection Online Access
description Neolamarckia cadamba is one of the medicinal plants used in the treatment of various diseases traditionally. This study was conducted to identify the phytochemical constituents of N. cadamba leaf extracts using gas chromatography mass spectrometry (GC-MS). Solvents with increasing polarities viz. hexane, petroleum ether, chloroform, ethyl acetate and methanol were used in this study. The solvent extracts were analyzed using GC-MS and the mass spectra of the compounds found in the respective extract were matched with the National Institute of Standards and Technology (NIST) library. A total of 26 compounds were identified and the major chemical constituents were n-hexadecanoic acid (44.88%), hexadecanoic acid ethyl ester (17.96%) and octadecanoic acid ethyl ester (11.71%). Some of the identified compounds have been reported to possess various biological activities such as antioxidant, antimicrobial, anesthetic, antiseptic, antidiabetic, hypocholesterolemic and etc. The results thus concluded that N. cadamba leaves possess various potent bioactive compounds and is recommended as a plant of phytopharmaceutical importance.
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spelling unimas-55862022-01-26T03:01:54Z http://ir.unimas.my/id/eprint/5586/ Gc-Ms Analysis Of Phytochemical Constituents In Leaf Extracts Of Neolamarckia Cadamba (Rubiaceae) From Malaysia Mohamed, Zaky Zayed Fasihuddin Badruddin, Ahmad Wei-Seng, Ho Shek-Ling, Pang RA0421 Public health. Hygiene. Preventive Medicine SB Plant culture Neolamarckia cadamba is one of the medicinal plants used in the treatment of various diseases traditionally. This study was conducted to identify the phytochemical constituents of N. cadamba leaf extracts using gas chromatography mass spectrometry (GC-MS). Solvents with increasing polarities viz. hexane, petroleum ether, chloroform, ethyl acetate and methanol were used in this study. The solvent extracts were analyzed using GC-MS and the mass spectra of the compounds found in the respective extract were matched with the National Institute of Standards and Technology (NIST) library. A total of 26 compounds were identified and the major chemical constituents were n-hexadecanoic acid (44.88%), hexadecanoic acid ethyl ester (17.96%) and octadecanoic acid ethyl ester (11.71%). Some of the identified compounds have been reported to possess various biological activities such as antioxidant, antimicrobial, anesthetic, antiseptic, antidiabetic, hypocholesterolemic and etc. The results thus concluded that N. cadamba leaves possess various potent bioactive compounds and is recommended as a plant of phytopharmaceutical importance. Innovare Academic Sciences 2014 Article PeerReviewed text en http://ir.unimas.my/id/eprint/5586/1/GC-MS.pdf Mohamed, Zaky Zayed and Fasihuddin Badruddin, Ahmad and Wei-Seng, Ho and Shek-Ling, Pang (2014) Gc-Ms Analysis Of Phytochemical Constituents In Leaf Extracts Of Neolamarckia Cadamba (Rubiaceae) From Malaysia. International Journal of Pharmacy and Pharmaceutical Sciences, 6 (9). ISSN 0975-1491 http://innovareacademics.in/journals/index.php/ijpps/article/view/1824
spellingShingle RA0421 Public health. Hygiene. Preventive Medicine
SB Plant culture
Mohamed, Zaky Zayed
Fasihuddin Badruddin, Ahmad
Wei-Seng, Ho
Shek-Ling, Pang
Gc-Ms Analysis Of Phytochemical Constituents In Leaf Extracts Of Neolamarckia Cadamba (Rubiaceae) From Malaysia
title Gc-Ms Analysis Of Phytochemical Constituents In Leaf Extracts Of Neolamarckia Cadamba (Rubiaceae) From Malaysia
title_full Gc-Ms Analysis Of Phytochemical Constituents In Leaf Extracts Of Neolamarckia Cadamba (Rubiaceae) From Malaysia
title_fullStr Gc-Ms Analysis Of Phytochemical Constituents In Leaf Extracts Of Neolamarckia Cadamba (Rubiaceae) From Malaysia
title_full_unstemmed Gc-Ms Analysis Of Phytochemical Constituents In Leaf Extracts Of Neolamarckia Cadamba (Rubiaceae) From Malaysia
title_short Gc-Ms Analysis Of Phytochemical Constituents In Leaf Extracts Of Neolamarckia Cadamba (Rubiaceae) From Malaysia
title_sort gc-ms analysis of phytochemical constituents in leaf extracts of neolamarckia cadamba (rubiaceae) from malaysia
topic RA0421 Public health. Hygiene. Preventive Medicine
SB Plant culture
url http://ir.unimas.my/id/eprint/5586/
http://ir.unimas.my/id/eprint/5586/
http://ir.unimas.my/id/eprint/5586/1/GC-MS.pdf