Genealogical study using mitochondrial DNA

This study examines the inheritance of maternal mitochondria DNA of a selected family. The sequence analysis was done by analyzing the mitochondrial D-loop region which are the hypervariable region I (HVR I), hypervariable region II (HVR II) and hypervariable region III (HVRIII). A total of 54 bucc...

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Main Author: Lora, Anak Johi
Format: Final Year Project Report / IMRAD
Language:English
Published: Universiti Malaysia Sarawak, (UNIMAS) 2011
Subjects:
Online Access:http://ir.unimas.my/id/eprint/5310/
http://ir.unimas.my/id/eprint/5310/8/Lora.pdf
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author Lora, Anak Johi
author_facet Lora, Anak Johi
author_sort Lora, Anak Johi
building UNIMAS Institutional Repository
collection Online Access
description This study examines the inheritance of maternal mitochondria DNA of a selected family. The sequence analysis was done by analyzing the mitochondrial D-loop region which are the hypervariable region I (HVR I), hypervariable region II (HVR II) and hypervariable region III (HVRIII). A total of 54 buccal cell samples collected from 54 individuals of the selected family. Phylogenetic analysis was done using bootstrap test of Neighbor- Joining (NJ) and pairwise distance was to determine the genetic distance among the family members. The result of the phylogenetic analysis indicated that HVR I was the most hypervariable region compared to HVR II and HVR III. However, the combinations of the entire three HVR regions produce the best results regarding the genealogical relationship among individual members of the family
first_indexed 2025-11-15T06:11:00Z
format Final Year Project Report / IMRAD
id unimas-5310
institution Universiti Malaysia Sarawak
institution_category Local University
language English
last_indexed 2025-11-15T06:11:00Z
publishDate 2011
publisher Universiti Malaysia Sarawak, (UNIMAS)
recordtype eprints
repository_type Digital Repository
spelling unimas-53102023-12-11T07:59:08Z http://ir.unimas.my/id/eprint/5310/ Genealogical study using mitochondrial DNA Lora, Anak Johi Q Science (General) This study examines the inheritance of maternal mitochondria DNA of a selected family. The sequence analysis was done by analyzing the mitochondrial D-loop region which are the hypervariable region I (HVR I), hypervariable region II (HVR II) and hypervariable region III (HVRIII). A total of 54 buccal cell samples collected from 54 individuals of the selected family. Phylogenetic analysis was done using bootstrap test of Neighbor- Joining (NJ) and pairwise distance was to determine the genetic distance among the family members. The result of the phylogenetic analysis indicated that HVR I was the most hypervariable region compared to HVR II and HVR III. However, the combinations of the entire three HVR regions produce the best results regarding the genealogical relationship among individual members of the family Universiti Malaysia Sarawak, (UNIMAS) 2011 Final Year Project Report / IMRAD NonPeerReviewed text en http://ir.unimas.my/id/eprint/5310/8/Lora.pdf Lora, Anak Johi (2011) Genealogical study using mitochondrial DNA. [Final Year Project Report / IMRAD] (Unpublished)
spellingShingle Q Science (General)
Lora, Anak Johi
Genealogical study using mitochondrial DNA
title Genealogical study using mitochondrial DNA
title_full Genealogical study using mitochondrial DNA
title_fullStr Genealogical study using mitochondrial DNA
title_full_unstemmed Genealogical study using mitochondrial DNA
title_short Genealogical study using mitochondrial DNA
title_sort genealogical study using mitochondrial dna
topic Q Science (General)
url http://ir.unimas.my/id/eprint/5310/
http://ir.unimas.my/id/eprint/5310/8/Lora.pdf