Design and fabrication of metered dose nasal spray
Nasal sprays are used for the nasal delivery of drugs. These drugs generally are used to alleviate cold or allergy symptoms such as nasal congestion. Nasal sprays generally consist of four parts which is the container closure system, pump mechanism, bottle cap and the nozzle. Atomizer had been used...
| Main Author: | |
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| Format: | Final Year Project Report / IMRAD |
| Language: | English English |
| Published: |
Universiti Malaysia Sarawak, UNIMAS
2008
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| Subjects: | |
| Online Access: | http://ir.unimas.my/id/eprint/4514/ http://ir.unimas.my/id/eprint/4514/1/Gan.pdf http://ir.unimas.my/id/eprint/4514/4/Gan%20full.pdf |
| _version_ | 1848835442055577600 |
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| author | Jameson, Gan |
| author_facet | Jameson, Gan |
| author_sort | Jameson, Gan |
| building | UNIMAS Institutional Repository |
| collection | Online Access |
| description | Nasal sprays are used for the nasal delivery of drugs. These drugs generally are used to alleviate cold or allergy symptoms such as nasal congestion. Nasal sprays
generally consist of four parts which is the container closure system, pump mechanism, bottle cap and the nozzle. Atomizer had been used in the applications of
nasal spray for some time. Atomization is the process of converting a bulk liquid into a cluster of spray or mist. Axiomatic Design is used to identify the weaknesses
associated with the existing nasal spray. A new design is proposed to improve the weaknesses and effectiveness. A pressure-swirl atomizer is utilized to create better
atomization and mixing of drugs. Pressure-swirl atomizer creates a wider spray angle and mistier spray droplets. The pressure- swirl nozzle produces a solid cone spray
and distributes the drug evenly in small liquid droplets. This will increase the rate of absorption into nasal moist wall. CATIA V4® software is used to create the design the component blueprint. Fabrication is done using CNC machine for better strength. Meanwhile, the COSMOSFloWorks® 2004 is used to simulate the flow inside the nozzle with a predetermined parameter. The pressure and inlet volume flow are also determined. Experiments are done to determine the spray pattern and angle of spray dispersion. |
| first_indexed | 2025-11-15T06:07:56Z |
| format | Final Year Project Report / IMRAD |
| id | unimas-4514 |
| institution | Universiti Malaysia Sarawak |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T06:07:56Z |
| publishDate | 2008 |
| publisher | Universiti Malaysia Sarawak, UNIMAS |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | unimas-45142023-07-03T07:58:40Z http://ir.unimas.my/id/eprint/4514/ Design and fabrication of metered dose nasal spray Jameson, Gan R Medicine (General) T Technology (General) Nasal sprays are used for the nasal delivery of drugs. These drugs generally are used to alleviate cold or allergy symptoms such as nasal congestion. Nasal sprays generally consist of four parts which is the container closure system, pump mechanism, bottle cap and the nozzle. Atomizer had been used in the applications of nasal spray for some time. Atomization is the process of converting a bulk liquid into a cluster of spray or mist. Axiomatic Design is used to identify the weaknesses associated with the existing nasal spray. A new design is proposed to improve the weaknesses and effectiveness. A pressure-swirl atomizer is utilized to create better atomization and mixing of drugs. Pressure-swirl atomizer creates a wider spray angle and mistier spray droplets. The pressure- swirl nozzle produces a solid cone spray and distributes the drug evenly in small liquid droplets. This will increase the rate of absorption into nasal moist wall. CATIA V4® software is used to create the design the component blueprint. Fabrication is done using CNC machine for better strength. Meanwhile, the COSMOSFloWorks® 2004 is used to simulate the flow inside the nozzle with a predetermined parameter. The pressure and inlet volume flow are also determined. Experiments are done to determine the spray pattern and angle of spray dispersion. Universiti Malaysia Sarawak, UNIMAS 2008 Final Year Project Report / IMRAD NonPeerReviewed text en http://ir.unimas.my/id/eprint/4514/1/Gan.pdf text en http://ir.unimas.my/id/eprint/4514/4/Gan%20full.pdf Jameson, Gan (2008) Design and fabrication of metered dose nasal spray. [Final Year Project Report / IMRAD] (Unpublished) |
| spellingShingle | R Medicine (General) T Technology (General) Jameson, Gan Design and fabrication of metered dose nasal spray |
| title | Design and fabrication of metered dose nasal spray |
| title_full | Design and fabrication of metered dose nasal spray |
| title_fullStr | Design and fabrication of metered dose nasal spray |
| title_full_unstemmed | Design and fabrication of metered dose nasal spray |
| title_short | Design and fabrication of metered dose nasal spray |
| title_sort | design and fabrication of metered dose nasal spray |
| topic | R Medicine (General) T Technology (General) |
| url | http://ir.unimas.my/id/eprint/4514/ http://ir.unimas.my/id/eprint/4514/1/Gan.pdf http://ir.unimas.my/id/eprint/4514/4/Gan%20full.pdf |