Characterization of an unusual adenovirus strain, Sibu 97

n adenovirus isolate, SIBU97, associated with an unexplained cluster of deaths of children with fatal acute myocardial dysfunction in Sarawak was characterized and compared with other human adenoviruses. The research is study the sequence comparisons with GenBank of portions of the SIBU97 genome tha...

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Main Author: Perera, David
Format: Thesis
Language:English
Published: Universiti Malaysia Sarawak, (UNIMAS) 2005
Subjects:
Online Access:http://ir.unimas.my/id/eprint/3835/
http://ir.unimas.my/id/eprint/3835/1/David%20Perera%20ft.pdf
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author Perera, David
author_facet Perera, David
author_sort Perera, David
building UNIMAS Institutional Repository
collection Online Access
description n adenovirus isolate, SIBU97, associated with an unexplained cluster of deaths of children with fatal acute myocardial dysfunction in Sarawak was characterized and compared with other human adenoviruses. The research is study the sequence comparisons with GenBank of portions of the SIBU97 genome that include the E1, E2, and E3 transcript regions showed that it shared >94% identity to human species B adenoviruses and simian adenovirus type 21. A comparison of restriction digest profiles of SIBU97 with prototype species B adenoviruses and several European Ad21 variants revealed profiles generated with Bam H1, Sma ! and Kpn 1 that differed from the other adenoviruses but were closely related to prototype Ad21.
first_indexed 2025-11-15T06:05:50Z
format Thesis
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institution Universiti Malaysia Sarawak
institution_category Local University
language English
last_indexed 2025-11-15T06:05:50Z
publishDate 2005
publisher Universiti Malaysia Sarawak, (UNIMAS)
recordtype eprints
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spelling unimas-38352023-06-22T09:27:00Z http://ir.unimas.my/id/eprint/3835/ Characterization of an unusual adenovirus strain, Sibu 97 Perera, David QR Microbiology n adenovirus isolate, SIBU97, associated with an unexplained cluster of deaths of children with fatal acute myocardial dysfunction in Sarawak was characterized and compared with other human adenoviruses. The research is study the sequence comparisons with GenBank of portions of the SIBU97 genome that include the E1, E2, and E3 transcript regions showed that it shared >94% identity to human species B adenoviruses and simian adenovirus type 21. A comparison of restriction digest profiles of SIBU97 with prototype species B adenoviruses and several European Ad21 variants revealed profiles generated with Bam H1, Sma ! and Kpn 1 that differed from the other adenoviruses but were closely related to prototype Ad21. Universiti Malaysia Sarawak, (UNIMAS) 2005 Thesis NonPeerReviewed text en http://ir.unimas.my/id/eprint/3835/1/David%20Perera%20ft.pdf Perera, David (2005) Characterization of an unusual adenovirus strain, Sibu 97. PhD thesis, Universiti Malaysia Sarawak, (UNIMAS).
spellingShingle QR Microbiology
Perera, David
Characterization of an unusual adenovirus strain, Sibu 97
title Characterization of an unusual adenovirus strain, Sibu 97
title_full Characterization of an unusual adenovirus strain, Sibu 97
title_fullStr Characterization of an unusual adenovirus strain, Sibu 97
title_full_unstemmed Characterization of an unusual adenovirus strain, Sibu 97
title_short Characterization of an unusual adenovirus strain, Sibu 97
title_sort characterization of an unusual adenovirus strain, sibu 97
topic QR Microbiology
url http://ir.unimas.my/id/eprint/3835/
http://ir.unimas.my/id/eprint/3835/1/David%20Perera%20ft.pdf