Development of Pseudo-nitzschia species-specific oligonucleotide primers for ribosomal intergenic spacer analysis

A study was carried out to determine the community structure of Pseudo-nitzschia species based on ribosomal intergenic spacer analysis (RISA). A molecular approach was carried out by using the secondary structure of the internal transcribed spacers (ITSs) transcripts to characterize the genetic vari...

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Main Authors: Teng, Sing-Tung, Lim, Hong-Chang, Lim, Po-Teen, Leaw, Chui-Pin
Format: Proceeding
Language:English
Published: Universiti Malaysia Sarawak 2013
Subjects:
Online Access:http://ir.unimas.my/id/eprint/337/
http://ir.unimas.my/id/eprint/337/1/development_of_pseudo-nitzschia_abstract.pdf
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author Teng, Sing-Tung
Lim, Hong-Chang
Lim, Po-Teen
Leaw, Chui-Pin
author_facet Teng, Sing-Tung
Lim, Hong-Chang
Lim, Po-Teen
Leaw, Chui-Pin
author_sort Teng, Sing-Tung
building UNIMAS Institutional Repository
collection Online Access
description A study was carried out to determine the community structure of Pseudo-nitzschia species based on ribosomal intergenic spacer analysis (RISA). A molecular approach was carried out by using the secondary structure of the internal transcribed spacers (ITSs) transcripts to characterize the genetic variability of Pseudo-nitzschia species. Clonal cultures used were grown in SWII medium at 26°C under 14: 10 hour light: dark photo cycle. Genomic DNA was extracted and used for ITS region amplification and sequencing. The sequences obtained were used to predict the RNA secondary structure. Sequence-structure alignment was performed with related taxa to identify the sequence signatures. Pseudo-nitzschia species- and genus-specific oligonucleotide primers were designed in silico based on the secondary structure information. The designed specific primers were tested for the development of a genotyping system
first_indexed 2025-11-15T05:53:17Z
format Proceeding
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institution Universiti Malaysia Sarawak
institution_category Local University
language English
last_indexed 2025-11-15T05:53:17Z
publishDate 2013
publisher Universiti Malaysia Sarawak
recordtype eprints
repository_type Digital Repository
spelling unimas-3372015-08-10T06:53:28Z http://ir.unimas.my/id/eprint/337/ Development of Pseudo-nitzschia species-specific oligonucleotide primers for ribosomal intergenic spacer analysis Teng, Sing-Tung Lim, Hong-Chang Lim, Po-Teen Leaw, Chui-Pin SH Aquaculture. Fisheries. Angling A study was carried out to determine the community structure of Pseudo-nitzschia species based on ribosomal intergenic spacer analysis (RISA). A molecular approach was carried out by using the secondary structure of the internal transcribed spacers (ITSs) transcripts to characterize the genetic variability of Pseudo-nitzschia species. Clonal cultures used were grown in SWII medium at 26°C under 14: 10 hour light: dark photo cycle. Genomic DNA was extracted and used for ITS region amplification and sequencing. The sequences obtained were used to predict the RNA secondary structure. Sequence-structure alignment was performed with related taxa to identify the sequence signatures. Pseudo-nitzschia species- and genus-specific oligonucleotide primers were designed in silico based on the secondary structure information. The designed specific primers were tested for the development of a genotyping system Universiti Malaysia Sarawak 2013 Proceeding PeerReviewed text en http://ir.unimas.my/id/eprint/337/1/development_of_pseudo-nitzschia_abstract.pdf Teng, Sing-Tung and Lim, Hong-Chang and Lim, Po-Teen and Leaw, Chui-Pin (2013) Development of Pseudo-nitzschia species-specific oligonucleotide primers for ribosomal intergenic spacer analysis. In: 9th Malaysia Genetics Congress (Appreciating the Richness of Nature Through Genetics). http://www.researchgate.net/publication/230779085_Development_of_Pseudo-nitzschia_species-specific_oligonucleotide_primers_for_ribosomal_intergenic_spacer_analysis
spellingShingle SH Aquaculture. Fisheries. Angling
Teng, Sing-Tung
Lim, Hong-Chang
Lim, Po-Teen
Leaw, Chui-Pin
Development of Pseudo-nitzschia species-specific oligonucleotide primers for ribosomal intergenic spacer analysis
title Development of Pseudo-nitzschia species-specific oligonucleotide primers for ribosomal intergenic spacer analysis
title_full Development of Pseudo-nitzschia species-specific oligonucleotide primers for ribosomal intergenic spacer analysis
title_fullStr Development of Pseudo-nitzschia species-specific oligonucleotide primers for ribosomal intergenic spacer analysis
title_full_unstemmed Development of Pseudo-nitzschia species-specific oligonucleotide primers for ribosomal intergenic spacer analysis
title_short Development of Pseudo-nitzschia species-specific oligonucleotide primers for ribosomal intergenic spacer analysis
title_sort development of pseudo-nitzschia species-specific oligonucleotide primers for ribosomal intergenic spacer analysis
topic SH Aquaculture. Fisheries. Angling
url http://ir.unimas.my/id/eprint/337/
http://ir.unimas.my/id/eprint/337/
http://ir.unimas.my/id/eprint/337/1/development_of_pseudo-nitzschia_abstract.pdf