Characterization of the Saxitoxin Biosynthetic Starting Gene, sxta in the Toxic Dinoflagellate Alexandrium tamiyavanichii

Recently, molecular genetics of the Saxitoxin (STX) biosynthesis pathway has become one of the major focuses in paralytic shellfish poisoning (PSP) toxin-related studies after the recent discovery of STX biosynthetic genes in toxic cyanobacteria and later in the toxic dinoflagellates. Here we descri...

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Bibliographic Details
Main Authors: Kieng, Soon Hii, Po, Teen Lim, Toh, Hii Tan, Chui, Pin Leaw
Format: Proceeding
Language:English
Published: Universiti Malaysia Sarawak, (UNIMAS) 2012
Subjects:
Online Access:http://ir.unimas.my/id/eprint/3193/
http://ir.unimas.my/id/eprint/3193/1/Characterization%20of%20the%20Saxitoxin%20Biosynthetic%20Starting%20Gene%2C%20sxta%20in%20the%20Toxic%20Dinoflagellate%20Alexandrium%20tamiyavanichii.pdf
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Summary:Recently, molecular genetics of the Saxitoxin (STX) biosynthesis pathway has become one of the major focuses in paralytic shellfish poisoning (PSP) toxin-related studies after the recent discovery of STX biosynthetic genes in toxic cyanobacteria and later in the toxic dinoflagellates. Here we described the two domains of sxtA, SAM-dependent methyltransferase coding gene, sxtA1 and the class II aminotransferase coding gene, sxtA4 from a toxic strain of Alexandrium tamiyavanichii isolated from Samariang, Sarawak.