Detection of Neovascularization in Diabetic Retinopathy

Diabetic retinopathy has become an increasingly important cause of blindness. Nevertheless, vision loss can be prevented from early detection of diabetic retinopathy and monitor with regular examination. Common automatic detection of retinal abnormalities is for microaneurysms, hemorrhages, hard exu...

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Main Authors: Siti Syafinah, Ahmad Hassan, Bong, D.B.L, Mallika, Premsenthil
Format: Article
Language:English
Published: Society for Imaging Informatics in Medicine 2012
Subjects:
Online Access:http://ir.unimas.my/id/eprint/2987/
http://ir.unimas.my/id/eprint/2987/1/10.1007%252Fs10278-011-9418-6
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author Siti Syafinah, Ahmad Hassan
Bong, D.B.L
Mallika, Premsenthil
author_facet Siti Syafinah, Ahmad Hassan
Bong, D.B.L
Mallika, Premsenthil
author_sort Siti Syafinah, Ahmad Hassan
building UNIMAS Institutional Repository
collection Online Access
description Diabetic retinopathy has become an increasingly important cause of blindness. Nevertheless, vision loss can be prevented from early detection of diabetic retinopathy and monitor with regular examination. Common automatic detection of retinal abnormalities is for microaneurysms, hemorrhages, hard exudates, and cotton wool spot. However, there is a worse case of retinal abnormality, but not much research was done to detect it. It is neovascularization where new blood vessels grow due to extensive lack of oxygen in the retinal capillaries. This paper shows that various combination of techniques such as image normalization, compactness classifier, morphology-based operator, Gaussian filtering, and thresholding techniques were used in developing of neovascularization detection. A function matrix box was added in order to classify the neovascularization from natural blood vessel. A region-based neovascularization classification was attempted as a diagnostic accuracy. The developed method was tested on images from different database sources with varying quality and image resolution. It shows that specificity and sensitivity results were 89.4% and 63.9%, respectively. The proposed approach yield encouraging results for future development.
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spelling unimas-29872016-04-19T07:01:07Z http://ir.unimas.my/id/eprint/2987/ Detection of Neovascularization in Diabetic Retinopathy Siti Syafinah, Ahmad Hassan Bong, D.B.L Mallika, Premsenthil TK Electrical engineering. Electronics Nuclear engineering Diabetic retinopathy has become an increasingly important cause of blindness. Nevertheless, vision loss can be prevented from early detection of diabetic retinopathy and monitor with regular examination. Common automatic detection of retinal abnormalities is for microaneurysms, hemorrhages, hard exudates, and cotton wool spot. However, there is a worse case of retinal abnormality, but not much research was done to detect it. It is neovascularization where new blood vessels grow due to extensive lack of oxygen in the retinal capillaries. This paper shows that various combination of techniques such as image normalization, compactness classifier, morphology-based operator, Gaussian filtering, and thresholding techniques were used in developing of neovascularization detection. A function matrix box was added in order to classify the neovascularization from natural blood vessel. A region-based neovascularization classification was attempted as a diagnostic accuracy. The developed method was tested on images from different database sources with varying quality and image resolution. It shows that specificity and sensitivity results were 89.4% and 63.9%, respectively. The proposed approach yield encouraging results for future development. Society for Imaging Informatics in Medicine 2012 Article NonPeerReviewed text en http://ir.unimas.my/id/eprint/2987/1/10.1007%252Fs10278-011-9418-6 Siti Syafinah, Ahmad Hassan and Bong, D.B.L and Mallika, Premsenthil (2012) Detection of Neovascularization in Diabetic Retinopathy. Journal of Digital Imaging, 25 (3). pp. 437-444. http://www.springerlink.com/content/40n1x15820v3k1r2/
spellingShingle TK Electrical engineering. Electronics Nuclear engineering
Siti Syafinah, Ahmad Hassan
Bong, D.B.L
Mallika, Premsenthil
Detection of Neovascularization in Diabetic Retinopathy
title Detection of Neovascularization in Diabetic Retinopathy
title_full Detection of Neovascularization in Diabetic Retinopathy
title_fullStr Detection of Neovascularization in Diabetic Retinopathy
title_full_unstemmed Detection of Neovascularization in Diabetic Retinopathy
title_short Detection of Neovascularization in Diabetic Retinopathy
title_sort detection of neovascularization in diabetic retinopathy
topic TK Electrical engineering. Electronics Nuclear engineering
url http://ir.unimas.my/id/eprint/2987/
http://ir.unimas.my/id/eprint/2987/
http://ir.unimas.my/id/eprint/2987/1/10.1007%252Fs10278-011-9418-6