Site-Specific Topoisomerase I-Mediated DNA Cleavage Induced by Nogalamycin: A Potential Role of Ligand-Induced DNA Bending at a Distal Site

QR Code

Site-Specific Topoisomerase I-Mediated DNA Cleavage Induced by Nogalamycin: A Potential Role of Ligand-Induced DNA Bending at a Distal Site

Sai Peng Sim, Daniel S. Pilch and LEroy F. Liu

Bibliographic Details
Main Authors:	Sim, S.P, Pilch, D.S., Liu, L.F.
Format:	Article
Language:	English
Published:	Biochemistry 2000
Subjects:	Q Science (General) R Medicine (General)
Online Access:	http://ir.unimas.my/id/eprint/2478/ http://ir.unimas.my/id/eprint/2478/1/Site-Specific%20Topoisomerase%20I-Mediated%20DNA%20Cleavage%20Induced%20by%20Nogalamycin%20A%20Potential%20Role%20of%20Ligand-Induced%20DNA%20Bending%20at%20a%20Distal%20Site.pdf

Similar Items

Heterocyclic bibenzimidazole derivatives as topoisomerase I inhibitors
by: Jin, S., et al.
Published: (2000)

2″-Substituted 5-phenylterbenzimidazoles as topoisomerase I poisons
by: Rangarajan, M., et al.
Published: (2000)

Synthesis, Characterization, Oxidative Dna Cleavage And Dna Binding Studies Of Mixed Ligands Copper(Ii) Complexes
by: Tan, Yi Han
Published: (2013)

Species-specific kinetics and zonation of hepatic DNA synthesis induced by ligands of PPARα
by: Al Kholaifi, Abdullah, et al.
Published: (2008)

Specific inhibition of ectodomain shedding of glycoprotein lba by targeting its juxtamembrane shedding cleavage site
by: Liang, X, et al.
Published: (2013)

Nucleolytic Cleavage of the Mixed Lineage Leukemia Breakpoint Cluster Region during Apoptosis
by: Sim, S.P, et al.
Published: (2001)

Expression Of Recombinant Human Dna Topoisomerase In Pichia Pastoris And Analysis Of Its Activity
by: Chan, Mooi Kwai
Published: (2017)

Topoisomerase I inhibition and cytotoxicity of 5-Bromo- and 5-Phenylterbenzimidazoles
by: Rangarajan, M., et al.
Published: (2000)

Structure, magnetic property and DNA cleavage ability of heterometal Mn2IIINi2II complex with ONO tridentate ligands
by: Ding, Y., et al.
Published: (2012)

In silico evaluation of usnic acid derivatives to discover potential antibacterial drugs against DNA gyrase B and DNA topoisomerase IV
by: Miah, Roney, et al.
Published: (2023)

Substituted benzo[i]phenanthridines as mammalian topoisomerase-Targeting agents
by: Makhey, D., et al.
Published: (2003)

Synthesis, Characterization And Dna Cleavage Ability Of Cobalt(II) And Zinc(II) Complexes
by: Goh , Siu Mun
Published: (2010)

2,3-Dimethoxybenzo[i]phenanthridines_ topoisomerase I-targeting anticancer agents
by: Lia, D., et al.
Published: (2002)

8,9-Methylenedioxybenzo[i]phenanthridines_ Topoisomerase I-Targeting activity and cytotoxicity
by: Li, D., et al.
Published: (2003)

Comparing the expression of human DNA topoisomerase I in KM71H and X33 strains of Pichia pastoris
by: Ruo, Ping Ang, et al.
Published: (2016)

Effects Of Camptothecin On Pichia Pastoris Strain Smd1168h Expressing Dna Topoisomerase I On Agar Plates
by: Devi Vadiveloo, Sajetra
Published: (2020)

Sequence analysis of the fusion (f) protein cleavage site of four Newcastle disease virus isolates
by: Ramanujam, Priadarishni, et al.
Published: (2004)

High cell density and latent membrane protein 1 expression induce cleavage of the mixed lineage leukemia gene at 11q23 in nasopharyngeal carcinoma cell line
by: Yee, P.H.C, et al.
Published: (2010)

Assessing the use of eDNA metabarcoding to monitor mine site restoration
by: van der Heyde, Mieke Elisabeth
Published: (2021)

Molecular dynamics simulations of ligand-induced backbone conformational changes in the binding site of the periplasmic lysine-, arginine-, ornithine-binding protein
by: Yang, A., et al.
Published: (2008)

Helicase binding to DnaI exposes a cryptic DNA-binding site during helicase loading in Bacillus subtilis
by: Ioannou, Charikleia, et al.
Published: (2006)

DNA metabarcoding—a new approach to fauna monitoring in mine site restoration
by: Fernandes, K., et al.
Published: (2018)

n-cutting site of DNA splicing language for single string and palindromic rule
by: Nooradelena, Mohd Ruslim, et al.
Published: (2022)

Caspase-8-mediated PAR-4 cleavage is required for TNFα-induced apoptosis
by: Treude, Fabian, et al.
Published: (2014)

Molecular characterisation and pathotyping of recently isolated Newcastle disease virus isolates based on F protein’s cleavage site
by: Shahrestani, Kiarash Roohani, et al.
Published: (2013)

DNA binding, nucleolytic properties, and topoisomerase i inhibition of ternary copper(ii) complexes of 1, 10-phenanthroline and chiral amino acid
by: Chong, James Kok Uei
Published: (2012)

Assessment of DNA strand breakage in streptozotocin-induced diabetic Rats
by: Siti Balkis Budin,, et al.
Published: (2005)

Untwisting of the DNA helix stimulates the endonuclease activity of Bacillus subtilis Nth at AP sites
by: Collier, Christopher, et al.
Published: (2011)

A single active site in the mariner transposase cleaves DNA strands of opposite polarity
by: Claeys Bouuaert, Corentin, et al.
Published: (2017)

Invertebrate DNA metabarcoding reveals changes in communities across mine site restoration chronosequences
by: Fernandes, Kristen, et al.
Published: (2019)

Site-Selective Bioconjugation via Interception of Free-Radical-Induced Dechalcogenation
by: Griffiths, Rhys
Published: (2021)

In utero exposure to cigarette chemicals induces sex-specific disruption of one-carbon metabolism and DNA methylation in the human fetal liver
by: Drake, Amanda J., et al.
Published: (2015)

Production of recombinant p53 protein by PCR-based site directed mutagenesis of plasmid DNA
by: Bakhtiar, M. Taher, et al.
Published: (2010)

Crystal structure, DNA binding studies, nucleolytic property and topoisomerase I inhibition of zinc complex with 1,10-phenanthroline and 3 methyl-picolinic acid
by: Seng, Hoi Ling, et al.
Published: (2010)

PO-1077 Comparison of in vivo and theoretical assessment of radiation-induced DNA damage
by: Ebert, M., et al.
Published: (2015)

Application of high resolution melting for detection of induced DNA polymorphism in Curcuma alismatifolia
by: Taheri, Sima, et al.
Published: (2014)

The Escherichia coli motA flagellar gene as a potential integration site for large synthetic DNA
by: Yip, Chee-Hoo, et al.
Published: (2019)

Cytotoxicity and DNA cleavage studies of salicylhydroxamic acid and its Ni(II), Cu(II) and Zn(II) complexes / Nor Haslini Wahid
by: Wahid, Nor Haslini
Published: (2009)

Factors affecting the nucleolytic cleavage of DNA by (N,N′-ethylenendiaminediacetato)metal(II) complexes, M(edda). Crystal structure of Co(edda)
by: Ng, Chew Hee, et al.
Published: (2006)

Site-specific ground response analysis at a site in the affected area of the 2016 Pidie Jaya earthquake
by: H., Yunita, et al.
Published: (2020)