Acral melanoma of the extremities_a study of 33 cases Sarawakian patients
cral melanoma involve the non-pigmented palmoplantar and subungual areas and are commonly seen among Asians. Patients commonly display advanced stage of disease at presentation. It may appear unnoticed and mimic benign lesions. Methods: Data for this retrospective study was retrieved from Histopatho...
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| Format: | Article |
| Language: | English |
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Medical Journal of Malaysia
2012
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| Online Access: | http://ir.unimas.my/id/eprint/2209/ http://ir.unimas.my/id/eprint/2209/1/Acral%20melanoma%20of%20the%20extremities_a%20study%20of%2033%20cases%20Sarawakian%20patients.pdf |
| _version_ | 1848834931802767360 |
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| author | Zainal, A.I Zulkarnaen, M. Norlida, D.K Syed Alwi, S.A.R |
| author_facet | Zainal, A.I Zulkarnaen, M. Norlida, D.K Syed Alwi, S.A.R |
| author_sort | Zainal, A.I |
| building | UNIMAS Institutional Repository |
| collection | Online Access |
| description | cral melanoma involve the non-pigmented palmoplantar and subungual areas and are commonly seen among Asians. Patients commonly display advanced stage of disease at presentation. It may appear unnoticed and mimic benign lesions. Methods: Data for this retrospective study was retrieved from Histopathology Unit, Sarawak General Hospital, Malaysia archive from 2003 to 2009. Result: 62.3% cases of malignant melanoma were acral melanoma. The mean age of diagnosis was 64.3±12.1. The involved sites were the heel (39.4%), middle and frontal plantar area (24.2%), toe (24.2%) and web spaces (9.1%). The clinical presentations were; an enlarging mass (60.6%), nonhealing ulcer (24.2%) and abnormal pigmented lesion (15.2%). Most cases exhibited Breslow thickness >4.00 mm (87.9%) and Clark’s levels V (50%). The majority showed moderate (non brisk) tumour infiltrating lymphocytes (57.6%). Ulceration (84.8%) and lymphovascular involvement were seen (24.2%). Conclusion: Acral melanoma is the commonest malignant melanoma in this Sarawakian cohort. Most of the cases presented with advanced stage disease. |
| first_indexed | 2025-11-15T05:59:49Z |
| format | Article |
| id | unimas-2209 |
| institution | Universiti Malaysia Sarawak |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T05:59:49Z |
| publishDate | 2012 |
| publisher | Medical Journal of Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | unimas-22092015-03-19T01:49:05Z http://ir.unimas.my/id/eprint/2209/ Acral melanoma of the extremities_a study of 33 cases Sarawakian patients Zainal, A.I Zulkarnaen, M. Norlida, D.K Syed Alwi, S.A.R Q Science (General) R Medicine (General) cral melanoma involve the non-pigmented palmoplantar and subungual areas and are commonly seen among Asians. Patients commonly display advanced stage of disease at presentation. It may appear unnoticed and mimic benign lesions. Methods: Data for this retrospective study was retrieved from Histopathology Unit, Sarawak General Hospital, Malaysia archive from 2003 to 2009. Result: 62.3% cases of malignant melanoma were acral melanoma. The mean age of diagnosis was 64.3±12.1. The involved sites were the heel (39.4%), middle and frontal plantar area (24.2%), toe (24.2%) and web spaces (9.1%). The clinical presentations were; an enlarging mass (60.6%), nonhealing ulcer (24.2%) and abnormal pigmented lesion (15.2%). Most cases exhibited Breslow thickness >4.00 mm (87.9%) and Clark’s levels V (50%). The majority showed moderate (non brisk) tumour infiltrating lymphocytes (57.6%). Ulceration (84.8%) and lymphovascular involvement were seen (24.2%). Conclusion: Acral melanoma is the commonest malignant melanoma in this Sarawakian cohort. Most of the cases presented with advanced stage disease. Medical Journal of Malaysia 2012 Article NonPeerReviewed text en http://ir.unimas.my/id/eprint/2209/1/Acral%20melanoma%20of%20the%20extremities_a%20study%20of%2033%20cases%20Sarawakian%20patients.pdf Zainal, A.I and Zulkarnaen, M. and Norlida, D.K and Syed Alwi, S.A.R (2012) Acral melanoma of the extremities_a study of 33 cases Sarawakian patients. Medical Journal of Malaysia, 67 (1). |
| spellingShingle | Q Science (General) R Medicine (General) Zainal, A.I Zulkarnaen, M. Norlida, D.K Syed Alwi, S.A.R Acral melanoma of the extremities_a study of 33 cases Sarawakian patients |
| title | Acral melanoma of the extremities_a study of 33 cases Sarawakian patients |
| title_full | Acral melanoma of the extremities_a study of 33 cases Sarawakian patients |
| title_fullStr | Acral melanoma of the extremities_a study of 33 cases Sarawakian patients |
| title_full_unstemmed | Acral melanoma of the extremities_a study of 33 cases Sarawakian patients |
| title_short | Acral melanoma of the extremities_a study of 33 cases Sarawakian patients |
| title_sort | acral melanoma of the extremities_a study of 33 cases sarawakian patients |
| topic | Q Science (General) R Medicine (General) |
| url | http://ir.unimas.my/id/eprint/2209/ http://ir.unimas.my/id/eprint/2209/1/Acral%20melanoma%20of%20the%20extremities_a%20study%20of%2033%20cases%20Sarawakian%20patients.pdf |