Expression Trend of Selected Ribosomal Protein Genes in Nasopharyngeal Carcinoma

Ribosomal proteins are traditionally associated with protein biosynthesis until recent studies that implicated their extraribosomal functions in human diseases and cancers. Our previous studies using GeneFishingTM DEG method and microarray revealed underexpression of three ribosomal protein genes,...

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Main Authors: Sim, Edmund, Ling, Teck Yee, Tiong, Thung-Sing, Selva, Subramaniam, Khoo, Alan
Format: Article
Language:English
Published: My Jurnal 2012
Subjects:
Online Access:http://ir.unimas.my/id/eprint/2150/
http://ir.unimas.my/id/eprint/2150/1/Expression%20Trend%20of%20Selected%20Ribosomal%20Protein%20Genes%20in%20Nasopharyngeal%20Carcinoma.pdf
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author Sim, Edmund
Ling, Teck Yee
Tiong, Thung-Sing
Selva, Subramaniam
Khoo, Alan
author_facet Sim, Edmund
Ling, Teck Yee
Tiong, Thung-Sing
Selva, Subramaniam
Khoo, Alan
author_sort Sim, Edmund
building UNIMAS Institutional Repository
collection Online Access
description Ribosomal proteins are traditionally associated with protein biosynthesis until recent studies that implicated their extraribosomal functions in human diseases and cancers. Our previous studies using GeneFishingTM DEG method and microarray revealed underexpression of three ribosomal protein genes, RPS26, RPS27, and RPL32 in cancer of the nasopharynx. Herein, we investigated the expression pattern and nucleotide sequence integrity of these genes in nasopharyngeal carcinoma to further delineate their involvement in tumourigenesis. The relationship of expression level with clinicopathologic factors was also statistically studied.
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institution Universiti Malaysia Sarawak
institution_category Local University
language English
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publishDate 2012
publisher My Jurnal
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spelling unimas-21502015-03-19T06:40:33Z http://ir.unimas.my/id/eprint/2150/ Expression Trend of Selected Ribosomal Protein Genes in Nasopharyngeal Carcinoma Sim, Edmund Ling, Teck Yee Tiong, Thung-Sing Selva, Subramaniam Khoo, Alan AC Collections. Series. Collected works Q Science (General) Ribosomal proteins are traditionally associated with protein biosynthesis until recent studies that implicated their extraribosomal functions in human diseases and cancers. Our previous studies using GeneFishingTM DEG method and microarray revealed underexpression of three ribosomal protein genes, RPS26, RPS27, and RPL32 in cancer of the nasopharynx. Herein, we investigated the expression pattern and nucleotide sequence integrity of these genes in nasopharyngeal carcinoma to further delineate their involvement in tumourigenesis. The relationship of expression level with clinicopathologic factors was also statistically studied. My Jurnal 2012 Article NonPeerReviewed text en http://ir.unimas.my/id/eprint/2150/1/Expression%20Trend%20of%20Selected%20Ribosomal%20Protein%20Genes%20in%20Nasopharyngeal%20Carcinoma.pdf Sim, Edmund and Ling, Teck Yee and Tiong, Thung-Sing and Selva, Subramaniam and Khoo, Alan (2012) Expression Trend of Selected Ribosomal Protein Genes in Nasopharyngeal Carcinoma. Malays J Med Sci. 2012 ; 19(4) : 23-30. http://www.myjurnal.my/
spellingShingle AC Collections. Series. Collected works
Q Science (General)
Sim, Edmund
Ling, Teck Yee
Tiong, Thung-Sing
Selva, Subramaniam
Khoo, Alan
Expression Trend of Selected Ribosomal Protein Genes in Nasopharyngeal Carcinoma
title Expression Trend of Selected Ribosomal Protein Genes in Nasopharyngeal Carcinoma
title_full Expression Trend of Selected Ribosomal Protein Genes in Nasopharyngeal Carcinoma
title_fullStr Expression Trend of Selected Ribosomal Protein Genes in Nasopharyngeal Carcinoma
title_full_unstemmed Expression Trend of Selected Ribosomal Protein Genes in Nasopharyngeal Carcinoma
title_short Expression Trend of Selected Ribosomal Protein Genes in Nasopharyngeal Carcinoma
title_sort expression trend of selected ribosomal protein genes in nasopharyngeal carcinoma
topic AC Collections. Series. Collected works
Q Science (General)
url http://ir.unimas.my/id/eprint/2150/
http://ir.unimas.my/id/eprint/2150/
http://ir.unimas.my/id/eprint/2150/1/Expression%20Trend%20of%20Selected%20Ribosomal%20Protein%20Genes%20in%20Nasopharyngeal%20Carcinoma.pdf