Synthesis and antibacterial study of organotin(IV) complexes containing hydrazinopyridine ligand [Sintesis dan kajian antibakteria kompleks organostanum(IV) yang mengandungi ligan hidrazinopiridin]
Nowadays, the studies on organotin(IV) complexes with hydrazone ligand become more interesting due to their potential in various applications including medicinal area. In our recent studies, four new organotin(IV) complexes MeSnCl2(C12H12N4) (2), BuSnCl2(C12H12N4) (3), PhSnCl2(C12H12N4) (4) and Ph2S...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The Malaysian Analytical Sciences Society
2017
|
| Subjects: | |
| Online Access: | http://ir.unimas.my/id/eprint/18937/ http://ir.unimas.my/id/eprint/18937/3/SYNTHESIS.pdf |
| _version_ | 1848838613641461760 |
|---|---|
| author | Dayang Norafizan, Awang Chee Monica Lulo, Rodis Norziah, Saat Zainab, Ngaini Ainaa Nadiah, Abd Halim |
| author_facet | Dayang Norafizan, Awang Chee Monica Lulo, Rodis Norziah, Saat Zainab, Ngaini Ainaa Nadiah, Abd Halim |
| author_sort | Dayang Norafizan, Awang Chee |
| building | UNIMAS Institutional Repository |
| collection | Online Access |
| description | Nowadays, the studies on organotin(IV) complexes with hydrazone ligand become more interesting due to their potential in various applications including medicinal area. In our recent studies, four new organotin(IV) complexes MeSnCl2(C12H12N4) (2), BuSnCl2(C12H12N4) (3), PhSnCl2(C12H12N4) (4) and Ph2SnCl(C12H12N4) (5) were synthesized by the direct reaction of methyl-2-pyridylketone-2-hydrazinopyridine ligand (1) and organotin(IV) chloride(s) in absolute methanol. These complexes have been characterized by UV-Visible, FT-IR, 1H and 13C NMR spectroscopies. All of the synthesized compounds were screened for antibacterial activity against Escherichia coli and Staphylococcus aureus. However, the complexes showed weak activity against the bacteria compared to the free ligand. |
| first_indexed | 2025-11-15T06:58:20Z |
| format | Article |
| id | unimas-18937 |
| institution | Universiti Malaysia Sarawak |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T06:58:20Z |
| publishDate | 2017 |
| publisher | The Malaysian Analytical Sciences Society |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | unimas-189372023-08-09T08:19:38Z http://ir.unimas.my/id/eprint/18937/ Synthesis and antibacterial study of organotin(IV) complexes containing hydrazinopyridine ligand [Sintesis dan kajian antibakteria kompleks organostanum(IV) yang mengandungi ligan hidrazinopiridin] Dayang Norafizan, Awang Chee Monica Lulo, Rodis Norziah, Saat Zainab, Ngaini Ainaa Nadiah, Abd Halim QD Chemistry Nowadays, the studies on organotin(IV) complexes with hydrazone ligand become more interesting due to their potential in various applications including medicinal area. In our recent studies, four new organotin(IV) complexes MeSnCl2(C12H12N4) (2), BuSnCl2(C12H12N4) (3), PhSnCl2(C12H12N4) (4) and Ph2SnCl(C12H12N4) (5) were synthesized by the direct reaction of methyl-2-pyridylketone-2-hydrazinopyridine ligand (1) and organotin(IV) chloride(s) in absolute methanol. These complexes have been characterized by UV-Visible, FT-IR, 1H and 13C NMR spectroscopies. All of the synthesized compounds were screened for antibacterial activity against Escherichia coli and Staphylococcus aureus. However, the complexes showed weak activity against the bacteria compared to the free ligand. The Malaysian Analytical Sciences Society 2017 Article PeerReviewed text en http://ir.unimas.my/id/eprint/18937/3/SYNTHESIS.pdf Dayang Norafizan, Awang Chee and Monica Lulo, Rodis and Norziah, Saat and Zainab, Ngaini and Ainaa Nadiah, Abd Halim (2017) Synthesis and antibacterial study of organotin(IV) complexes containing hydrazinopyridine ligand [Sintesis dan kajian antibakteria kompleks organostanum(IV) yang mengandungi ligan hidrazinopiridin]. Malaysian Journal of Analytical Sciences, 21 (5). pp. 1143-1150. ISSN 13942506 http://www.ukm.my/mjas/mjas2018/ DOI: 10.17576/mjas-2017-2105-17 |
| spellingShingle | QD Chemistry Dayang Norafizan, Awang Chee Monica Lulo, Rodis Norziah, Saat Zainab, Ngaini Ainaa Nadiah, Abd Halim Synthesis and antibacterial study of organotin(IV) complexes containing hydrazinopyridine ligand [Sintesis dan kajian antibakteria kompleks organostanum(IV) yang mengandungi ligan hidrazinopiridin] |
| title | Synthesis and antibacterial study of organotin(IV) complexes containing hydrazinopyridine ligand [Sintesis dan kajian antibakteria kompleks organostanum(IV) yang mengandungi ligan hidrazinopiridin] |
| title_full | Synthesis and antibacterial study of organotin(IV) complexes containing hydrazinopyridine ligand [Sintesis dan kajian antibakteria kompleks organostanum(IV) yang mengandungi ligan hidrazinopiridin] |
| title_fullStr | Synthesis and antibacterial study of organotin(IV) complexes containing hydrazinopyridine ligand [Sintesis dan kajian antibakteria kompleks organostanum(IV) yang mengandungi ligan hidrazinopiridin] |
| title_full_unstemmed | Synthesis and antibacterial study of organotin(IV) complexes containing hydrazinopyridine ligand [Sintesis dan kajian antibakteria kompleks organostanum(IV) yang mengandungi ligan hidrazinopiridin] |
| title_short | Synthesis and antibacterial study of organotin(IV) complexes containing hydrazinopyridine ligand [Sintesis dan kajian antibakteria kompleks organostanum(IV) yang mengandungi ligan hidrazinopiridin] |
| title_sort | synthesis and antibacterial study of organotin(iv) complexes containing hydrazinopyridine ligand [sintesis dan kajian antibakteria kompleks organostanum(iv) yang mengandungi ligan hidrazinopiridin] |
| topic | QD Chemistry |
| url | http://ir.unimas.my/id/eprint/18937/ http://ir.unimas.my/id/eprint/18937/ http://ir.unimas.my/id/eprint/18937/ http://ir.unimas.my/id/eprint/18937/3/SYNTHESIS.pdf |