Accuracy of Modified Checklist for Autism in Toddlers (M-CHAT) in Detecting Autism and Other Developmental Disorders in Community Clinics

This study determined the accuracy of Modified Checklist for Autism in Toddlers (M-CHAT) in detecting toddlers with autism spectrum disorder (ASD) and other developmental disorders (DD) in community mother and child health clinics. We analysed 19,297 eligible toddlers (15–36 months) who had M-CHAT p...

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Main Authors: Toh, Teck‑Hock, Tan, Vivian Wee-Yen, Lau, Peter Sie-Teck, Andrew, Kiyu
Format: Article
Language:English
Published: Springer New York LLC. 2017
Subjects:
Online Access:http://ir.unimas.my/id/eprint/18696/
http://ir.unimas.my/id/eprint/18696/7/Accuracy%20of%20Modified%20Checklist%20for%20Autism%20in%20Toddlers%20%28abstract%29.pdf
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author Toh, Teck‑Hock
Tan, Vivian Wee-Yen
Lau, Peter Sie-Teck
Andrew, Kiyu
author_facet Toh, Teck‑Hock
Tan, Vivian Wee-Yen
Lau, Peter Sie-Teck
Andrew, Kiyu
author_sort Toh, Teck‑Hock
building UNIMAS Institutional Repository
collection Online Access
description This study determined the accuracy of Modified Checklist for Autism in Toddlers (M-CHAT) in detecting toddlers with autism spectrum disorder (ASD) and other developmental disorders (DD) in community mother and child health clinics. We analysed 19,297 eligible toddlers (15–36 months) who had M-CHAT performed in 2006–2011. Overall sensitivities for detecting ASD and all DD were poor but better in the 21 to <27 months and 27–36-month age cohorts (54.5–64.3%). Although positive predictive value (PPV) was poor for ASD, especially the younger cohort, positive M-CHAT helped in detecting all DD (PPV = 81.6%). This suggested M-CHAT for screening ASD was accurate for older cohorts (>21 months) and a useful screening tool for all DD.
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spelling unimas-186962017-11-30T01:36:48Z http://ir.unimas.my/id/eprint/18696/ Accuracy of Modified Checklist for Autism in Toddlers (M-CHAT) in Detecting Autism and Other Developmental Disorders in Community Clinics Toh, Teck‑Hock Tan, Vivian Wee-Yen Lau, Peter Sie-Teck Andrew, Kiyu RJ101 Child Health. Child health services This study determined the accuracy of Modified Checklist for Autism in Toddlers (M-CHAT) in detecting toddlers with autism spectrum disorder (ASD) and other developmental disorders (DD) in community mother and child health clinics. We analysed 19,297 eligible toddlers (15–36 months) who had M-CHAT performed in 2006–2011. Overall sensitivities for detecting ASD and all DD were poor but better in the 21 to <27 months and 27–36-month age cohorts (54.5–64.3%). Although positive predictive value (PPV) was poor for ASD, especially the younger cohort, positive M-CHAT helped in detecting all DD (PPV = 81.6%). This suggested M-CHAT for screening ASD was accurate for older cohorts (>21 months) and a useful screening tool for all DD. Springer New York LLC. 2017-09-02 Article PeerReviewed text en http://ir.unimas.my/id/eprint/18696/7/Accuracy%20of%20Modified%20Checklist%20for%20Autism%20in%20Toddlers%20%28abstract%29.pdf Toh, Teck‑Hock and Tan, Vivian Wee-Yen and Lau, Peter Sie-Teck and Andrew, Kiyu (2017) Accuracy of Modified Checklist for Autism in Toddlers (M-CHAT) in Detecting Autism and Other Developmental Disorders in Community Clinics. Journal of Autism and Developmental Disorders. pp. 1-8. ISSN 0162-3257 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85028764085&doi=10.1007%2fs10803-017-3287-x&partnerID=40&md5=21bce2407197b8b1e43b4420d274861b DOI: 10.1007/s10803-017-3287-x
spellingShingle RJ101 Child Health. Child health services
Toh, Teck‑Hock
Tan, Vivian Wee-Yen
Lau, Peter Sie-Teck
Andrew, Kiyu
Accuracy of Modified Checklist for Autism in Toddlers (M-CHAT) in Detecting Autism and Other Developmental Disorders in Community Clinics
title Accuracy of Modified Checklist for Autism in Toddlers (M-CHAT) in Detecting Autism and Other Developmental Disorders in Community Clinics
title_full Accuracy of Modified Checklist for Autism in Toddlers (M-CHAT) in Detecting Autism and Other Developmental Disorders in Community Clinics
title_fullStr Accuracy of Modified Checklist for Autism in Toddlers (M-CHAT) in Detecting Autism and Other Developmental Disorders in Community Clinics
title_full_unstemmed Accuracy of Modified Checklist for Autism in Toddlers (M-CHAT) in Detecting Autism and Other Developmental Disorders in Community Clinics
title_short Accuracy of Modified Checklist for Autism in Toddlers (M-CHAT) in Detecting Autism and Other Developmental Disorders in Community Clinics
title_sort accuracy of modified checklist for autism in toddlers (m-chat) in detecting autism and other developmental disorders in community clinics
topic RJ101 Child Health. Child health services
url http://ir.unimas.my/id/eprint/18696/
http://ir.unimas.my/id/eprint/18696/
http://ir.unimas.my/id/eprint/18696/
http://ir.unimas.my/id/eprint/18696/7/Accuracy%20of%20Modified%20Checklist%20for%20Autism%20in%20Toddlers%20%28abstract%29.pdf