Superparamagnetic core-shell nanoparticles for biomedical applications

Superparamagnetic magnetite (Fe3O4) nanoparticles have been widely studied for various scientific and technological applications such as magnetic storage media, contrast agents for magnetic resonance imaging (MRI), biolabelling and separation of biomolecules, and magnetic targetted drug delivery. In...

Full description

Bibliographic Details
Main Authors: Suk, Fun Chin, Swaminatha Iyer, K., Raston, Colin L.
Format: Article
Language:English
Published: IEEE 2011
Subjects:
Online Access:http://ir.unimas.my/id/eprint/16658/
http://ir.unimas.my/id/eprint/16658/1/Superparamagnetic%20Core-Shell%20Nanoparticles%20for%20Biomedical%20Applications%20%28abstract%29.pdf
_version_ 1848838109326737408
author Suk, Fun Chin
Swaminatha Iyer, K.
Raston, Colin L.
author_facet Suk, Fun Chin
Swaminatha Iyer, K.
Raston, Colin L.
author_sort Suk, Fun Chin
building UNIMAS Institutional Repository
collection Online Access
description Superparamagnetic magnetite (Fe3O4) nanoparticles have been widely studied for various scientific and technological applications such as magnetic storage media, contrast agents for magnetic resonance imaging (MRI), biolabelling and separation of biomolecules, and magnetic targetted drug delivery. In the absence of surface coating, Fe3O4 nanoparticles tend to aggregate due to the Van der Waals forces coupled with the magnetic dipole-dipole attractions between the particles. In order to successfully prepare stable magnetite dispersions, any attractive forces between the nanoparticles must be overcome. In this study, magnetite nanoparticles have been prepared by chemical precipitation method. Gold (Au) and silver (Ag) are ideal coating for Fe3O4 nanoparticles due to their high chemical stability, biocompatibility, and their affinity for binding to amine/thiol terminal groups of organic molecules. In addition these coatings also render the Fe3O4 nanoparticles with plasmonic properties.
first_indexed 2025-11-15T06:50:20Z
format Article
id unimas-16658
institution Universiti Malaysia Sarawak
institution_category Local University
language English
last_indexed 2025-11-15T06:50:20Z
publishDate 2011
publisher IEEE
recordtype eprints
repository_type Digital Repository
spelling unimas-166582017-06-15T01:36:29Z http://ir.unimas.my/id/eprint/16658/ Superparamagnetic core-shell nanoparticles for biomedical applications Suk, Fun Chin Swaminatha Iyer, K. Raston, Colin L. QD Chemistry Superparamagnetic magnetite (Fe3O4) nanoparticles have been widely studied for various scientific and technological applications such as magnetic storage media, contrast agents for magnetic resonance imaging (MRI), biolabelling and separation of biomolecules, and magnetic targetted drug delivery. In the absence of surface coating, Fe3O4 nanoparticles tend to aggregate due to the Van der Waals forces coupled with the magnetic dipole-dipole attractions between the particles. In order to successfully prepare stable magnetite dispersions, any attractive forces between the nanoparticles must be overcome. In this study, magnetite nanoparticles have been prepared by chemical precipitation method. Gold (Au) and silver (Ag) are ideal coating for Fe3O4 nanoparticles due to their high chemical stability, biocompatibility, and their affinity for binding to amine/thiol terminal groups of organic molecules. In addition these coatings also render the Fe3O4 nanoparticles with plasmonic properties. IEEE 2011 Article PeerReviewed text en http://ir.unimas.my/id/eprint/16658/1/Superparamagnetic%20Core-Shell%20Nanoparticles%20for%20Biomedical%20Applications%20%28abstract%29.pdf Suk, Fun Chin and Swaminatha Iyer, K. and Raston, Colin L. (2011) Superparamagnetic core-shell nanoparticles for biomedical applications. International Conference on Enabling Science and Nanotechnology (ESciNano), 2010. ISSN ISBN: 978-1-4244-8854-4 http://ieeexplore.ieee.org/document/5700936/ DOI: 10.1109/ESCINANO.2010.5700936
spellingShingle QD Chemistry
Suk, Fun Chin
Swaminatha Iyer, K.
Raston, Colin L.
Superparamagnetic core-shell nanoparticles for biomedical applications
title Superparamagnetic core-shell nanoparticles for biomedical applications
title_full Superparamagnetic core-shell nanoparticles for biomedical applications
title_fullStr Superparamagnetic core-shell nanoparticles for biomedical applications
title_full_unstemmed Superparamagnetic core-shell nanoparticles for biomedical applications
title_short Superparamagnetic core-shell nanoparticles for biomedical applications
title_sort superparamagnetic core-shell nanoparticles for biomedical applications
topic QD Chemistry
url http://ir.unimas.my/id/eprint/16658/
http://ir.unimas.my/id/eprint/16658/
http://ir.unimas.my/id/eprint/16658/
http://ir.unimas.my/id/eprint/16658/1/Superparamagnetic%20Core-Shell%20Nanoparticles%20for%20Biomedical%20Applications%20%28abstract%29.pdf