An improved binary particle swarm optimization algorithm for DNA encoding enhancement

The accuracy of DNA computing highly depends on the DNA strands used in solving complex computations. As such, many approaches are proposed to design DNA oligonucleotides that are stable and unique. In this paper, an improved binary particle swarm optimization (IBPSO) algorithm is proposed and imple...

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Main Authors: Mohd Saufee, Muhammad, Krishna Veni, Selvan, Sharifah Masniah, Wan Masra
Format: Article
Language:English
Published: IEEE 2011
Subjects:
Online Access:http://ir.unimas.my/id/eprint/16643/
http://ir.unimas.my/id/eprint/16643/1/An%20Improved%20Binary%20Particle%20Swarm%20Optimization%20%28abstract%29.pdf
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author Mohd Saufee, Muhammad
Krishna Veni, Selvan
Sharifah Masniah, Wan Masra
author_facet Mohd Saufee, Muhammad
Krishna Veni, Selvan
Sharifah Masniah, Wan Masra
author_sort Mohd Saufee, Muhammad
building UNIMAS Institutional Repository
collection Online Access
description The accuracy of DNA computing highly depends on the DNA strands used in solving complex computations. As such, many approaches are proposed to design DNA oligonucleotides that are stable and unique. In this paper, an improved binary particle swarm optimization (IBPSO) algorithm is proposed and implemented. Four objective functions which are H-measure, similarity, hairpin and continuity are employed to define the uniqueness of designed sequences. The DNA words are constrained within a predefined range of GC-content and melting temperature. The performances and the ability of the algorithm to enhance the characteristics of generated DNA code words are analyzed. The results obtained show that this algorithm executes better sequences and did perform better compared to other optimization techniques. Moreover, it converges faster than the previously suggested binary particle swarm optimization algorithm.
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institution Universiti Malaysia Sarawak
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publishDate 2011
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spelling unimas-166432017-06-14T06:45:51Z http://ir.unimas.my/id/eprint/16643/ An improved binary particle swarm optimization algorithm for DNA encoding enhancement Mohd Saufee, Muhammad Krishna Veni, Selvan Sharifah Masniah, Wan Masra TK Electrical engineering. Electronics Nuclear engineering The accuracy of DNA computing highly depends on the DNA strands used in solving complex computations. As such, many approaches are proposed to design DNA oligonucleotides that are stable and unique. In this paper, an improved binary particle swarm optimization (IBPSO) algorithm is proposed and implemented. Four objective functions which are H-measure, similarity, hairpin and continuity are employed to define the uniqueness of designed sequences. The DNA words are constrained within a predefined range of GC-content and melting temperature. The performances and the ability of the algorithm to enhance the characteristics of generated DNA code words are analyzed. The results obtained show that this algorithm executes better sequences and did perform better compared to other optimization techniques. Moreover, it converges faster than the previously suggested binary particle swarm optimization algorithm. IEEE 2011 Article PeerReviewed text en http://ir.unimas.my/id/eprint/16643/1/An%20Improved%20Binary%20Particle%20Swarm%20Optimization%20%28abstract%29.pdf Mohd Saufee, Muhammad and Krishna Veni, Selvan and Sharifah Masniah, Wan Masra (2011) An improved binary particle swarm optimization algorithm for DNA encoding enhancement. IEEE Symposium on Swarm Intelligence (SIS), 2011. ISSN ISBN: 978-1-61284-052-9 http://ieeexplore.ieee.org/document/5952579/ DOI: 10.1109/SIS.2011.5952579
spellingShingle TK Electrical engineering. Electronics Nuclear engineering
Mohd Saufee, Muhammad
Krishna Veni, Selvan
Sharifah Masniah, Wan Masra
An improved binary particle swarm optimization algorithm for DNA encoding enhancement
title An improved binary particle swarm optimization algorithm for DNA encoding enhancement
title_full An improved binary particle swarm optimization algorithm for DNA encoding enhancement
title_fullStr An improved binary particle swarm optimization algorithm for DNA encoding enhancement
title_full_unstemmed An improved binary particle swarm optimization algorithm for DNA encoding enhancement
title_short An improved binary particle swarm optimization algorithm for DNA encoding enhancement
title_sort improved binary particle swarm optimization algorithm for dna encoding enhancement
topic TK Electrical engineering. Electronics Nuclear engineering
url http://ir.unimas.my/id/eprint/16643/
http://ir.unimas.my/id/eprint/16643/
http://ir.unimas.my/id/eprint/16643/
http://ir.unimas.my/id/eprint/16643/1/An%20Improved%20Binary%20Particle%20Swarm%20Optimization%20%28abstract%29.pdf