Avocado Oil Supplementation Modifies Cardiovascular Risk Profile Markers in a Rat Model of Sucrose-Induced Metabolic Changes

The purpose of this study was to evaluate the effects of avocado oil administration on biochemical markers of cardiovascular risk profile in rats with metabolic changes induced by sucrose ingestion. Twenty-five rats were divided into five groups: a control group (CG; basic diet), a sick group (MC;...

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Main Authors:	Octavio, Carvajal-Zarrabal, Cirilo Nolasco, Nolasco-Hipólito, M. Guadalupe, Aguilar-Uscanga, Guadalupe, Melo-Santiesteban, Hayward-Jones, Patricia M., Barradas-Dermitz, Dulce M.
Format:	Article
Language:	English
Published:	Hindawi Publishing Corporation 2014
Subjects:	QD Chemistry QR Microbiology
Online Access:	http://ir.unimas.my/id/eprint/16276/ http://ir.unimas.my/id/eprint/16276/1/Avocado%20Oil%20Supplementation%20Modifies%20Cardiovascular%20%28abstract%29.pdf

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author	Octavio, Carvajal-Zarrabal Cirilo Nolasco, Nolasco-Hipólito M. Guadalupe, Aguilar-Uscanga Guadalupe, Melo-Santiesteban Hayward-Jones, Patricia M. Barradas-Dermitz, Dulce M.
author_facet	Octavio, Carvajal-Zarrabal Cirilo Nolasco, Nolasco-Hipólito M. Guadalupe, Aguilar-Uscanga Guadalupe, Melo-Santiesteban Hayward-Jones, Patricia M. Barradas-Dermitz, Dulce M.
author_sort	Octavio, Carvajal-Zarrabal
building	UNIMAS Institutional Repository
collection	Online Access
description	The purpose of this study was to evaluate the effects of avocado oil administration on biochemical markers of cardiovascular risk profile in rats with metabolic changes induced by sucrose ingestion. Twenty-five rats were divided into five groups: a control group (CG; basic diet), a sick group (MC; basic diet plus 30% sucrose solution), and three other groups (MCao, MCac, and MCas; basic diet plus 30% sucrose solution plus olive oil and avocado oil extracted by centrifugation or using solvent, resp.). Glucose, total cholesterol, triglycerides, phospholipids, low- and high-density lipoproteins (LDL, HDL), very low-density lipoprotein (VLDL), lactic dehydrogenase, creatine kinase, and high sensitivity C-reactive protein concentration were analyzed. Avocado oil reduces TG, VLDL, and LDL levels, in the LDL case significantly so, without affecting HDL levels. An effect was exhibited by avocado oil similar to olive oil, with no significant difference between avocado oil extracted either by centrifugation or solvent in myocardial injury biochemical indicators.Avocado oil decreased hs-CRP levels, indicating that inflammatory processes were partially reversed. These findings suggested that avocado oil supplementation has a positive health outcome because it reduces inflammatory events and produces positive changes in the biochemical indicators studied, related to the development of metabolic syndrome.
first_indexed	2025-11-15T06:48:59Z
format	Article
id	unimas-16276
institution	Universiti Malaysia Sarawak
institution_category	Local University
language	English
last_indexed	2025-11-15T06:48:59Z
publishDate	2014
publisher	Hindawi Publishing Corporation
recordtype	eprints
repository_type	Digital Repository
spelling	unimas-162762017-05-17T06:24:32Z http://ir.unimas.my/id/eprint/16276/ Avocado Oil Supplementation Modifies Cardiovascular Risk Profile Markers in a Rat Model of Sucrose-Induced Metabolic Changes Octavio, Carvajal-Zarrabal Cirilo Nolasco, Nolasco-Hipólito M. Guadalupe, Aguilar-Uscanga Guadalupe, Melo-Santiesteban Hayward-Jones, Patricia M. Barradas-Dermitz, Dulce M. QD Chemistry QR Microbiology The purpose of this study was to evaluate the effects of avocado oil administration on biochemical markers of cardiovascular risk profile in rats with metabolic changes induced by sucrose ingestion. Twenty-five rats were divided into five groups: a control group (CG; basic diet), a sick group (MC; basic diet plus 30% sucrose solution), and three other groups (MCao, MCac, and MCas; basic diet plus 30% sucrose solution plus olive oil and avocado oil extracted by centrifugation or using solvent, resp.). Glucose, total cholesterol, triglycerides, phospholipids, low- and high-density lipoproteins (LDL, HDL), very low-density lipoprotein (VLDL), lactic dehydrogenase, creatine kinase, and high sensitivity C-reactive protein concentration were analyzed. Avocado oil reduces TG, VLDL, and LDL levels, in the LDL case significantly so, without affecting HDL levels. An effect was exhibited by avocado oil similar to olive oil, with no significant difference between avocado oil extracted either by centrifugation or solvent in myocardial injury biochemical indicators.Avocado oil decreased hs-CRP levels, indicating that inflammatory processes were partially reversed. These findings suggested that avocado oil supplementation has a positive health outcome because it reduces inflammatory events and produces positive changes in the biochemical indicators studied, related to the development of metabolic syndrome. Hindawi Publishing Corporation 2014 Article PeerReviewed text en http://ir.unimas.my/id/eprint/16276/1/Avocado%20Oil%20Supplementation%20Modifies%20Cardiovascular%20%28abstract%29.pdf Octavio, Carvajal-Zarrabal and Cirilo Nolasco, Nolasco-Hipólito and M. Guadalupe, Aguilar-Uscanga and Guadalupe, Melo-Santiesteban and Hayward-Jones, Patricia M. and Barradas-Dermitz, Dulce M. (2014) Avocado Oil Supplementation Modifies Cardiovascular Risk Profile Markers in a Rat Model of Sucrose-Induced Metabolic Changes. Disease Markers, 2014. ISSN 0278-0240 https://www.researchgate.net/publication/261362403 http://dx.doi.org/10.1155/2014/386425
spellingShingle	QD Chemistry QR Microbiology Octavio, Carvajal-Zarrabal Cirilo Nolasco, Nolasco-Hipólito M. Guadalupe, Aguilar-Uscanga Guadalupe, Melo-Santiesteban Hayward-Jones, Patricia M. Barradas-Dermitz, Dulce M. Avocado Oil Supplementation Modifies Cardiovascular Risk Profile Markers in a Rat Model of Sucrose-Induced Metabolic Changes
title	Avocado Oil Supplementation Modifies Cardiovascular Risk Profile Markers in a Rat Model of Sucrose-Induced Metabolic Changes
title_full	Avocado Oil Supplementation Modifies Cardiovascular Risk Profile Markers in a Rat Model of Sucrose-Induced Metabolic Changes
title_fullStr	Avocado Oil Supplementation Modifies Cardiovascular Risk Profile Markers in a Rat Model of Sucrose-Induced Metabolic Changes
title_full_unstemmed	Avocado Oil Supplementation Modifies Cardiovascular Risk Profile Markers in a Rat Model of Sucrose-Induced Metabolic Changes
title_short	Avocado Oil Supplementation Modifies Cardiovascular Risk Profile Markers in a Rat Model of Sucrose-Induced Metabolic Changes
title_sort	avocado oil supplementation modifies cardiovascular risk profile markers in a rat model of sucrose-induced metabolic changes
topic	QD Chemistry QR Microbiology
url	http://ir.unimas.my/id/eprint/16276/ http://ir.unimas.my/id/eprint/16276/ http://ir.unimas.my/id/eprint/16276/ http://ir.unimas.my/id/eprint/16276/1/Avocado%20Oil%20Supplementation%20Modifies%20Cardiovascular%20%28abstract%29.pdf

Avocado Oil Supplementation Modifies Cardiovascular Risk Profile Markers in a Rat Model of Sucrose-Induced Metabolic Changes

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