Late presentation of Nipah virus encephalitis and kinetics of the humoral immune response

Nipah virus is a newly discovered paramyxovirus transmitted directly from pigs to humans. During a large encephalitis outbreak in Malaysia and Singapore in 1998–9, most patients presented acutely. A 12 year old child is described who developed encephalitis 4 months after exposure to the virus. She w...

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Main Authors: Wong, See Chang, Ooi, Mong How, Wong, MNL, Tio, Phaik Hooi, Solomon, Tom, Cardosa, Mary Jane
Format: Article
Language:English
Published: BMJ Publishing Group Ltd 2001
Subjects:
Online Access:http://ir.unimas.my/id/eprint/15788/
http://ir.unimas.my/id/eprint/15788/1/Late%20presentation%20of%20Nipah%20virus%20encephalitis%20%28abstract%29.pdf
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author Wong, See Chang
Ooi, Mong How
Wong, MNL
Tio, Phaik Hooi
Solomon, Tom
Cardosa, Mary Jane
author_facet Wong, See Chang
Ooi, Mong How
Wong, MNL
Tio, Phaik Hooi
Solomon, Tom
Cardosa, Mary Jane
author_sort Wong, See Chang
building UNIMAS Institutional Repository
collection Online Access
description Nipah virus is a newly discovered paramyxovirus transmitted directly from pigs to humans. During a large encephalitis outbreak in Malaysia and Singapore in 1998–9, most patients presented acutely. A 12 year old child is described who developed encephalitis 4 months after exposure to the virus. She was diagnosed by a new indirect IgG enzyme linked immunosorbent assay (ELISA), which is also described. The late presentation and IgG subclass responses had similarities to subacute sclerosing panencephalitis. Nipah virus should be considered in patients with encephalitis even months after their possible exposure.
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publishDate 2001
publisher BMJ Publishing Group Ltd
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spelling unimas-157882017-04-03T07:04:02Z http://ir.unimas.my/id/eprint/15788/ Late presentation of Nipah virus encephalitis and kinetics of the humoral immune response Wong, See Chang Ooi, Mong How Wong, MNL Tio, Phaik Hooi Solomon, Tom Cardosa, Mary Jane Q Science (General) Nipah virus is a newly discovered paramyxovirus transmitted directly from pigs to humans. During a large encephalitis outbreak in Malaysia and Singapore in 1998–9, most patients presented acutely. A 12 year old child is described who developed encephalitis 4 months after exposure to the virus. She was diagnosed by a new indirect IgG enzyme linked immunosorbent assay (ELISA), which is also described. The late presentation and IgG subclass responses had similarities to subacute sclerosing panencephalitis. Nipah virus should be considered in patients with encephalitis even months after their possible exposure. BMJ Publishing Group Ltd 2001 Article PeerReviewed text en http://ir.unimas.my/id/eprint/15788/1/Late%20presentation%20of%20Nipah%20virus%20encephalitis%20%28abstract%29.pdf Wong, See Chang and Ooi, Mong How and Wong, MNL and Tio, Phaik Hooi and Solomon, Tom and Cardosa, Mary Jane (2001) Late presentation of Nipah virus encephalitis and kinetics of the humoral immune response. Journal of Neurology Neurosurgery & Psychiatry, 71. pp. 552-554. ISSN 1468-330X http://jnnp.bmj.com/content/71/4/552.full http://dx.doi.org/10.1136/jnnp.71.4.552
spellingShingle Q Science (General)
Wong, See Chang
Ooi, Mong How
Wong, MNL
Tio, Phaik Hooi
Solomon, Tom
Cardosa, Mary Jane
Late presentation of Nipah virus encephalitis and kinetics of the humoral immune response
title Late presentation of Nipah virus encephalitis and kinetics of the humoral immune response
title_full Late presentation of Nipah virus encephalitis and kinetics of the humoral immune response
title_fullStr Late presentation of Nipah virus encephalitis and kinetics of the humoral immune response
title_full_unstemmed Late presentation of Nipah virus encephalitis and kinetics of the humoral immune response
title_short Late presentation of Nipah virus encephalitis and kinetics of the humoral immune response
title_sort late presentation of nipah virus encephalitis and kinetics of the humoral immune response
topic Q Science (General)
url http://ir.unimas.my/id/eprint/15788/
http://ir.unimas.my/id/eprint/15788/
http://ir.unimas.my/id/eprint/15788/
http://ir.unimas.my/id/eprint/15788/1/Late%20presentation%20of%20Nipah%20virus%20encephalitis%20%28abstract%29.pdf