Diversity of Leptospira spp. in Rats and Environment from Urban Areas of Sarawak, Malaysia

Various prevalence studies on Leptospira in animals and humans, as well as environmental samples, had been conducted worldwide, includingMalaysia. However, limited studies have been documented on the presence of pathogenic, intermediate, and saprophytic Leptospira in selected animals and environme...

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Main Authors: Chai, Fung Pui, Lesley Maurice, Bilung, Kasing, Apun, Lela, Su’ut
Format: Article
Language:English
Published: Hindawi Limited 2017
Subjects:
Online Access:http://ir.unimas.my/id/eprint/15613/
http://ir.unimas.my/id/eprint/15613/1/Diversity%20of%20Leptospira%20spp.%20in%20Rats%20%28abstract%29.pdf
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author Chai, Fung Pui
Lesley Maurice, Bilung
Kasing, Apun
Lela, Su’ut
author_facet Chai, Fung Pui
Lesley Maurice, Bilung
Kasing, Apun
Lela, Su’ut
author_sort Chai, Fung Pui
building UNIMAS Institutional Repository
collection Online Access
description Various prevalence studies on Leptospira in animals and humans, as well as environmental samples, had been conducted worldwide, includingMalaysia. However, limited studies have been documented on the presence of pathogenic, intermediate, and saprophytic Leptospira in selected animals and environments. This study was therefore conducted to detect Leptospira spp. in rats, soil, and water from urban areas of Sarawak using the polymerase chain reaction (PCR) method. A total of 107 rats, 292 soil samples, and 324 water samples were collected fromApril 2014 to February 2015. Pathogenic Leptospira was present in 5.6% (6/107) of rats, 11.6% (34/292) of soil samples, and 1.9% (6/324) of water samples. Intermediate Leptospira was present in 2.7% (8/292) of soil samples and 1.9% (6/324) of water samples. Saprophytic Leptospira was present in 10.3% (11/107) of rats, 1.4% (4/292) of soil samples, and 0.3% (1/324) of water samples. From this study, 76 Leptospira spp. were isolated. Based on DNA sequencing, the dominant Leptospira spp. circulating in urban areas of Sarawak are pathogenic Leptospira noguchii, intermediate Leptospira wolffii serovar Khorat, and saprophytic Leptospirameyeri, respectively.Overall, this study provided important surveillance data on the prevalence of Leptospira spp. from rats and the environment, with dominant local serovars in urban areas of Sarawak.
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spelling unimas-156132017-05-22T06:09:20Z http://ir.unimas.my/id/eprint/15613/ Diversity of Leptospira spp. in Rats and Environment from Urban Areas of Sarawak, Malaysia Chai, Fung Pui Lesley Maurice, Bilung Kasing, Apun Lela, Su’ut SF Animal culture Various prevalence studies on Leptospira in animals and humans, as well as environmental samples, had been conducted worldwide, includingMalaysia. However, limited studies have been documented on the presence of pathogenic, intermediate, and saprophytic Leptospira in selected animals and environments. This study was therefore conducted to detect Leptospira spp. in rats, soil, and water from urban areas of Sarawak using the polymerase chain reaction (PCR) method. A total of 107 rats, 292 soil samples, and 324 water samples were collected fromApril 2014 to February 2015. Pathogenic Leptospira was present in 5.6% (6/107) of rats, 11.6% (34/292) of soil samples, and 1.9% (6/324) of water samples. Intermediate Leptospira was present in 2.7% (8/292) of soil samples and 1.9% (6/324) of water samples. Saprophytic Leptospira was present in 10.3% (11/107) of rats, 1.4% (4/292) of soil samples, and 0.3% (1/324) of water samples. From this study, 76 Leptospira spp. were isolated. Based on DNA sequencing, the dominant Leptospira spp. circulating in urban areas of Sarawak are pathogenic Leptospira noguchii, intermediate Leptospira wolffii serovar Khorat, and saprophytic Leptospirameyeri, respectively.Overall, this study provided important surveillance data on the prevalence of Leptospira spp. from rats and the environment, with dominant local serovars in urban areas of Sarawak. Hindawi Limited 2017 Article PeerReviewed text en http://ir.unimas.my/id/eprint/15613/1/Diversity%20of%20Leptospira%20spp.%20in%20Rats%20%28abstract%29.pdf Chai, Fung Pui and Lesley Maurice, Bilung and Kasing, Apun and Lela, Su’ut (2017) Diversity of Leptospira spp. in Rats and Environment from Urban Areas of Sarawak, Malaysia. Journal of Tropical Medicine, 2017. ISSN 1687-9686 https://www.hindawi.com/journals/jtm/2017/3760674/abs/ https://doi.org/10.1155/2017/3760674
spellingShingle SF Animal culture
Chai, Fung Pui
Lesley Maurice, Bilung
Kasing, Apun
Lela, Su’ut
Diversity of Leptospira spp. in Rats and Environment from Urban Areas of Sarawak, Malaysia
title Diversity of Leptospira spp. in Rats and Environment from Urban Areas of Sarawak, Malaysia
title_full Diversity of Leptospira spp. in Rats and Environment from Urban Areas of Sarawak, Malaysia
title_fullStr Diversity of Leptospira spp. in Rats and Environment from Urban Areas of Sarawak, Malaysia
title_full_unstemmed Diversity of Leptospira spp. in Rats and Environment from Urban Areas of Sarawak, Malaysia
title_short Diversity of Leptospira spp. in Rats and Environment from Urban Areas of Sarawak, Malaysia
title_sort diversity of leptospira spp. in rats and environment from urban areas of sarawak, malaysia
topic SF Animal culture
url http://ir.unimas.my/id/eprint/15613/
http://ir.unimas.my/id/eprint/15613/
http://ir.unimas.my/id/eprint/15613/
http://ir.unimas.my/id/eprint/15613/1/Diversity%20of%20Leptospira%20spp.%20in%20Rats%20%28abstract%29.pdf