Green synthesis and characterization of 3-carboxycoumarin and ethylcoumarin-3-carboxylate via Knoevenagel condensation
Environmentally benign, simple, efficient and clean syntheses of 3-carboxycoumarins and ethyl coumarin-3-carboxylate have been synthesized via Knoevenagel condensation using green catalysts such as aqueous extract of Acacia concinna pods and amino acids. These syntheses were carried out in solvents...
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| Format: | Article |
| Language: | English |
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Chemical Publishing Co
2017
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| Online Access: | http://ir.unimas.my/id/eprint/15428/ http://ir.unimas.my/id/eprint/15428/2/Green%20synthesis.pdf |
| _version_ | 1848837849905889280 |
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| author | Syed Salman, Shafqat Amirazam, Khan Misbahulain, Khan Shanti Faridah, Salleh Mohd Syahmi, Jamaludin Pang, Suh Cem |
| author_facet | Syed Salman, Shafqat Amirazam, Khan Misbahulain, Khan Shanti Faridah, Salleh Mohd Syahmi, Jamaludin Pang, Suh Cem |
| author_sort | Syed Salman, Shafqat |
| building | UNIMAS Institutional Repository |
| collection | Online Access |
| description | Environmentally benign, simple, efficient and clean syntheses of 3-carboxycoumarins and ethyl coumarin-3-carboxylate have been synthesized via Knoevenagel condensation using green catalysts such as aqueous extract of Acacia concinna pods and amino acids. These syntheses were carried out in solvents as well as solvent-less media. The yields obtained (between 86 % to 96 %) for the reactions were equal or better than those previously reported. The products were isolated, purified and characterized through melting points, TLC, IR, GC Mass and 1H NMR spectroscopy. The characterized molecules showed structural and compositional conformity with the predicted reactions. The green route used for these reactions has shown to be efficient in reducing the time of reaction and in avoiding the toxic nature of the catalysts employed in classical reaction |
| first_indexed | 2025-11-15T06:46:12Z |
| format | Article |
| id | unimas-15428 |
| institution | Universiti Malaysia Sarawak |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T06:46:12Z |
| publishDate | 2017 |
| publisher | Chemical Publishing Co |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | unimas-154282022-06-24T01:23:34Z http://ir.unimas.my/id/eprint/15428/ Green synthesis and characterization of 3-carboxycoumarin and ethylcoumarin-3-carboxylate via Knoevenagel condensation Syed Salman, Shafqat Amirazam, Khan Misbahulain, Khan Shanti Faridah, Salleh Mohd Syahmi, Jamaludin Pang, Suh Cem QD Chemistry TP Chemical technology Environmentally benign, simple, efficient and clean syntheses of 3-carboxycoumarins and ethyl coumarin-3-carboxylate have been synthesized via Knoevenagel condensation using green catalysts such as aqueous extract of Acacia concinna pods and amino acids. These syntheses were carried out in solvents as well as solvent-less media. The yields obtained (between 86 % to 96 %) for the reactions were equal or better than those previously reported. The products were isolated, purified and characterized through melting points, TLC, IR, GC Mass and 1H NMR spectroscopy. The characterized molecules showed structural and compositional conformity with the predicted reactions. The green route used for these reactions has shown to be efficient in reducing the time of reaction and in avoiding the toxic nature of the catalysts employed in classical reaction Chemical Publishing Co 2017 Article PeerReviewed text en http://ir.unimas.my/id/eprint/15428/2/Green%20synthesis.pdf Syed Salman, Shafqat and Amirazam, Khan and Misbahulain, Khan and Shanti Faridah, Salleh and Mohd Syahmi, Jamaludin and Pang, Suh Cem (2017) Green synthesis and characterization of 3-carboxycoumarin and ethylcoumarin-3-carboxylate via Knoevenagel condensation. Asian Journal of Chemistry, 29 (2). pp. 261-266. ISSN 0970-7077 http://www.asianjournalofchemistry.co.in/user/journal/viewarticle.aspx?ArticleID=29_2_5 DOI: 10.14233/ajchem.2017.20142 |
| spellingShingle | QD Chemistry TP Chemical technology Syed Salman, Shafqat Amirazam, Khan Misbahulain, Khan Shanti Faridah, Salleh Mohd Syahmi, Jamaludin Pang, Suh Cem Green synthesis and characterization of 3-carboxycoumarin and ethylcoumarin-3-carboxylate via Knoevenagel condensation |
| title | Green synthesis and characterization of 3-carboxycoumarin and ethylcoumarin-3-carboxylate via Knoevenagel condensation |
| title_full | Green synthesis and characterization of 3-carboxycoumarin and ethylcoumarin-3-carboxylate via Knoevenagel condensation |
| title_fullStr | Green synthesis and characterization of 3-carboxycoumarin and ethylcoumarin-3-carboxylate via Knoevenagel condensation |
| title_full_unstemmed | Green synthesis and characterization of 3-carboxycoumarin and ethylcoumarin-3-carboxylate via Knoevenagel condensation |
| title_short | Green synthesis and characterization of 3-carboxycoumarin and ethylcoumarin-3-carboxylate via Knoevenagel condensation |
| title_sort | green synthesis and characterization of 3-carboxycoumarin and ethylcoumarin-3-carboxylate via knoevenagel condensation |
| topic | QD Chemistry TP Chemical technology |
| url | http://ir.unimas.my/id/eprint/15428/ http://ir.unimas.my/id/eprint/15428/ http://ir.unimas.my/id/eprint/15428/ http://ir.unimas.my/id/eprint/15428/2/Green%20synthesis.pdf |