Evaluation of antibacterial activity of neolamarckia macrophylla leaf extract

Tremendous research were done to extract bioactive compound from natural product especially plant which can be used as an alternative drugs to treat infection. The evaluation of atntibacterial activity of Neolamarckia macrophylla leaves crude extract by using three method: maceration, Soxhlet and d...

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Main Author: Izzarul Atirah, binti Boestamam
Format: Final Year Project Report / IMRAD
Language:English
Published: Universiti Malaysia Sarawak, (UNIMAS) 2016
Subjects:
Online Access:http://ir.unimas.my/id/eprint/15357/
http://ir.unimas.my/id/eprint/15357/5/Izzarul%20Atirah.pdf
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author Izzarul Atirah, binti Boestamam
author_facet Izzarul Atirah, binti Boestamam
author_sort Izzarul Atirah, binti Boestamam
building UNIMAS Institutional Repository
collection Online Access
description Tremendous research were done to extract bioactive compound from natural product especially plant which can be used as an alternative drugs to treat infection. The evaluation of atntibacterial activity of Neolamarckia macrophylla leaves crude extract by using three method: maceration, Soxhlet and direct use was determined using disc diffusion method against medically important baceria such as Escherichia coli, Klebsiella sp., Pseudomonas aeruginos, Salmonella typhimuriu,, Listeria monocytogenes, Staphylococcus aureus and Bacillus cereus with different concentration (12.5%, 50%, 75% and 100%). The results showed that the inhibition growth varies among tested bacteria with maceration method gives better result compared ot other techniques used. Two solvents were used; ethanol and distilled water, and ethanol extradtion has better antinacterial acivity compared to aqueous extraction. This study provides preliminary results suggestisng that N. macrophylla can be used as a source of drug to fight infection.
first_indexed 2025-11-15T06:45:59Z
format Final Year Project Report / IMRAD
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institution Universiti Malaysia Sarawak
institution_category Local University
language English
last_indexed 2025-11-15T06:45:59Z
publishDate 2016
publisher Universiti Malaysia Sarawak, (UNIMAS)
recordtype eprints
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spelling unimas-153572024-04-12T08:34:16Z http://ir.unimas.my/id/eprint/15357/ Evaluation of antibacterial activity of neolamarckia macrophylla leaf extract Izzarul Atirah, binti Boestamam RS Pharmacy and materia medica SB Plant culture Tremendous research were done to extract bioactive compound from natural product especially plant which can be used as an alternative drugs to treat infection. The evaluation of atntibacterial activity of Neolamarckia macrophylla leaves crude extract by using three method: maceration, Soxhlet and direct use was determined using disc diffusion method against medically important baceria such as Escherichia coli, Klebsiella sp., Pseudomonas aeruginos, Salmonella typhimuriu,, Listeria monocytogenes, Staphylococcus aureus and Bacillus cereus with different concentration (12.5%, 50%, 75% and 100%). The results showed that the inhibition growth varies among tested bacteria with maceration method gives better result compared ot other techniques used. Two solvents were used; ethanol and distilled water, and ethanol extradtion has better antinacterial acivity compared to aqueous extraction. This study provides preliminary results suggestisng that N. macrophylla can be used as a source of drug to fight infection. Universiti Malaysia Sarawak, (UNIMAS) 2016 Final Year Project Report / IMRAD NonPeerReviewed text en http://ir.unimas.my/id/eprint/15357/5/Izzarul%20Atirah.pdf Izzarul Atirah, binti Boestamam (2016) Evaluation of antibacterial activity of neolamarckia macrophylla leaf extract. [Final Year Project Report / IMRAD] (Unpublished)
spellingShingle RS Pharmacy and materia medica
SB Plant culture
Izzarul Atirah, binti Boestamam
Evaluation of antibacterial activity of neolamarckia macrophylla leaf extract
title Evaluation of antibacterial activity of neolamarckia macrophylla leaf extract
title_full Evaluation of antibacterial activity of neolamarckia macrophylla leaf extract
title_fullStr Evaluation of antibacterial activity of neolamarckia macrophylla leaf extract
title_full_unstemmed Evaluation of antibacterial activity of neolamarckia macrophylla leaf extract
title_short Evaluation of antibacterial activity of neolamarckia macrophylla leaf extract
title_sort evaluation of antibacterial activity of neolamarckia macrophylla leaf extract
topic RS Pharmacy and materia medica
SB Plant culture
url http://ir.unimas.my/id/eprint/15357/
http://ir.unimas.my/id/eprint/15357/5/Izzarul%20Atirah.pdf