Synthesis and Characterization of Molecular Imprinting Polymer Microspheres of Piperine: Extraction of Piperine from Spiked Urine
Molecularly imprinted polymer (MIP) microspheres for Piperine were synthesized by precipitation polymerization with a noncovalent approach. In this research Piperine was used as a template, acrylic acid as a functional monomer, ethylene glycol dimethacrylate as a cross-linker, and 2,2′-azobisisobuty...
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| Format: | Article |
| Language: | English |
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Hindawi Publishing Corporation
2016
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| Online Access: | http://ir.unimas.my/id/eprint/15304/ http://ir.unimas.my/id/eprint/15304/1/Rachel%20Marcella.pdf |
| _version_ | 1848837825115455488 |
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| author | Roland, Rachel Marcella Bhawani, Showkat Ahmad |
| author_facet | Roland, Rachel Marcella Bhawani, Showkat Ahmad |
| author_sort | Roland, Rachel Marcella |
| building | UNIMAS Institutional Repository |
| collection | Online Access |
| description | Molecularly imprinted polymer (MIP) microspheres for Piperine were synthesized by precipitation polymerization with a noncovalent approach. In this research Piperine was used as a template, acrylic acid as a functional monomer, ethylene glycol dimethacrylate as a cross-linker, and 2,2′-azobisisobutyronitrile (AIBN) as an initiator and acetonitrile as a solvent. The imprinted and nonimprinted polymer particles were characterized by using Fourier transform infrared spectroscopy (FT-IR) and Scanning Electron Microscopy (SEM). The synthesized polymer particles were further evaluated for their rebinding efficiency by batch binding assay. The highly selected imprinted polymer for Piperine was MIP 3 with a composition (molar ratio) of 0.5: 3: 8, template: monomer: cross-linker, respectively. The MIP 3 exhibits highest binding capacity (84.94%) as compared to other imprinted and nonimprinted polymers. The extraction efficiency of highly selected imprinted polymer of Piperine from spiked urine was above 80%. |
| first_indexed | 2025-11-15T06:45:48Z |
| format | Article |
| id | unimas-15304 |
| institution | Universiti Malaysia Sarawak |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T06:45:48Z |
| publishDate | 2016 |
| publisher | Hindawi Publishing Corporation |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | unimas-153042022-02-08T06:20:04Z http://ir.unimas.my/id/eprint/15304/ Synthesis and Characterization of Molecular Imprinting Polymer Microspheres of Piperine: Extraction of Piperine from Spiked Urine Roland, Rachel Marcella Bhawani, Showkat Ahmad QD Chemistry Molecularly imprinted polymer (MIP) microspheres for Piperine were synthesized by precipitation polymerization with a noncovalent approach. In this research Piperine was used as a template, acrylic acid as a functional monomer, ethylene glycol dimethacrylate as a cross-linker, and 2,2′-azobisisobutyronitrile (AIBN) as an initiator and acetonitrile as a solvent. The imprinted and nonimprinted polymer particles were characterized by using Fourier transform infrared spectroscopy (FT-IR) and Scanning Electron Microscopy (SEM). The synthesized polymer particles were further evaluated for their rebinding efficiency by batch binding assay. The highly selected imprinted polymer for Piperine was MIP 3 with a composition (molar ratio) of 0.5: 3: 8, template: monomer: cross-linker, respectively. The MIP 3 exhibits highest binding capacity (84.94%) as compared to other imprinted and nonimprinted polymers. The extraction efficiency of highly selected imprinted polymer of Piperine from spiked urine was above 80%. Hindawi Publishing Corporation 2016 Article PeerReviewed text en http://ir.unimas.my/id/eprint/15304/1/Rachel%20Marcella.pdf Roland, Rachel Marcella and Bhawani, Showkat Ahmad (2016) Synthesis and Characterization of Molecular Imprinting Polymer Microspheres of Piperine: Extraction of Piperine from Spiked Urine. Journal of Analytical Methods in Chemistry, 2016. ISSN 20908865 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85005966777&doi=10.1155%2f2016%2f5671507&partnerID=40&md5=b953173a9d8f1da028f5dc3544b09cdc DOI: 10.1155/2016/5671507 |
| spellingShingle | QD Chemistry Roland, Rachel Marcella Bhawani, Showkat Ahmad Synthesis and Characterization of Molecular Imprinting Polymer Microspheres of Piperine: Extraction of Piperine from Spiked Urine |
| title | Synthesis and Characterization of Molecular Imprinting Polymer Microspheres of Piperine: Extraction of Piperine from Spiked Urine |
| title_full | Synthesis and Characterization of Molecular Imprinting Polymer Microspheres of Piperine: Extraction of Piperine from Spiked Urine |
| title_fullStr | Synthesis and Characterization of Molecular Imprinting Polymer Microspheres of Piperine: Extraction of Piperine from Spiked Urine |
| title_full_unstemmed | Synthesis and Characterization of Molecular Imprinting Polymer Microspheres of Piperine: Extraction of Piperine from Spiked Urine |
| title_short | Synthesis and Characterization of Molecular Imprinting Polymer Microspheres of Piperine: Extraction of Piperine from Spiked Urine |
| title_sort | synthesis and characterization of molecular imprinting polymer microspheres of piperine: extraction of piperine from spiked urine |
| topic | QD Chemistry |
| url | http://ir.unimas.my/id/eprint/15304/ http://ir.unimas.my/id/eprint/15304/ http://ir.unimas.my/id/eprint/15304/ http://ir.unimas.my/id/eprint/15304/1/Rachel%20Marcella.pdf |