Fabrication of cellulose aerogel from sugarcane bagasse as drug delivery carriers
Currently most of the aerogel-based drug delivery carriers are made from non-biodegradable materials, such as silica. In this study, highly porous cellulose aerogels with Brunauer-Emmett-Teller (BET) surface areas that varied between 22 m2 g-1 and 525 m2 g-1 were prepared from a sugarcane bagasse ce...
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| Format: | Article |
| Language: | English |
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Universiti Sains Malaysia
2016
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| Online Access: | http://ir.unimas.my/id/eprint/15302/ http://ir.unimas.my/id/eprint/15302/2/Fabrication%20of%20Cellulose%20-%20Copy.pdf |
| _version_ | 1848837824574390272 |
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| author | Chin, Sukfun Jimmy, Fiona Beragai Pang, Suhcem |
| author_facet | Chin, Sukfun Jimmy, Fiona Beragai Pang, Suhcem |
| author_sort | Chin, Sukfun |
| building | UNIMAS Institutional Repository |
| collection | Online Access |
| description | Currently most of the aerogel-based drug delivery carriers are made from non-biodegradable materials, such as silica. In this study, highly porous cellulose aerogels with Brunauer-Emmett-Teller (BET) surface areas that varied between 22 m2 g-1 and 525 m2 g-1 were prepared from a sugarcane bagasse cellulose solution of various concentrations. The potential utility of cellulose aerogels as controlled release carriers was evaluated by loading methylene blue (MB) as a model hydrophilic drug. The MB loading capacity and release kinetic profiles of cellulose aerogels were observed to be substantially influenced by their BET surface areas. Under optimum conditions, a maximum loading capacity of 6.4 mg MB mg-1 cellulose aerogel was achieved with sustained release of MB from cellulose aerogels at physiological pH over a period of 23 h |
| first_indexed | 2025-11-15T06:45:48Z |
| format | Article |
| id | unimas-15302 |
| institution | Universiti Malaysia Sarawak |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T06:45:48Z |
| publishDate | 2016 |
| publisher | Universiti Sains Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | unimas-153022022-05-24T08:35:29Z http://ir.unimas.my/id/eprint/15302/ Fabrication of cellulose aerogel from sugarcane bagasse as drug delivery carriers Chin, Sukfun Jimmy, Fiona Beragai Pang, Suhcem QD Chemistry Currently most of the aerogel-based drug delivery carriers are made from non-biodegradable materials, such as silica. In this study, highly porous cellulose aerogels with Brunauer-Emmett-Teller (BET) surface areas that varied between 22 m2 g-1 and 525 m2 g-1 were prepared from a sugarcane bagasse cellulose solution of various concentrations. The potential utility of cellulose aerogels as controlled release carriers was evaluated by loading methylene blue (MB) as a model hydrophilic drug. The MB loading capacity and release kinetic profiles of cellulose aerogels were observed to be substantially influenced by their BET surface areas. Under optimum conditions, a maximum loading capacity of 6.4 mg MB mg-1 cellulose aerogel was achieved with sustained release of MB from cellulose aerogels at physiological pH over a period of 23 h Universiti Sains Malaysia 2016 Article PeerReviewed text en http://ir.unimas.my/id/eprint/15302/2/Fabrication%20of%20Cellulose%20-%20Copy.pdf Chin, Sukfun and Jimmy, Fiona Beragai and Pang, Suhcem (2016) Fabrication of cellulose aerogel from sugarcane bagasse as drug delivery carriers. Journal of Physical Science, 27 (3). pp. 159-168. ISSN 16753402 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85002939757&doi=10.21315%2fjps2016.27.3.10&partnerID=40&md5=99b4f6e6a3f43a69cc8f3403fa0d06ae DOI: 10.21315/jps2016.27.3.10 |
| spellingShingle | QD Chemistry Chin, Sukfun Jimmy, Fiona Beragai Pang, Suhcem Fabrication of cellulose aerogel from sugarcane bagasse as drug delivery carriers |
| title | Fabrication of cellulose aerogel from sugarcane bagasse as drug delivery carriers |
| title_full | Fabrication of cellulose aerogel from sugarcane bagasse as drug delivery carriers |
| title_fullStr | Fabrication of cellulose aerogel from sugarcane bagasse as drug delivery carriers |
| title_full_unstemmed | Fabrication of cellulose aerogel from sugarcane bagasse as drug delivery carriers |
| title_short | Fabrication of cellulose aerogel from sugarcane bagasse as drug delivery carriers |
| title_sort | fabrication of cellulose aerogel from sugarcane bagasse as drug delivery carriers |
| topic | QD Chemistry |
| url | http://ir.unimas.my/id/eprint/15302/ http://ir.unimas.my/id/eprint/15302/ http://ir.unimas.my/id/eprint/15302/ http://ir.unimas.my/id/eprint/15302/2/Fabrication%20of%20Cellulose%20-%20Copy.pdf |