Molecular phylogeny of modern coxsackievirus A16
A phylogenetic analysis of VP1 and VP4 nucleotide sequences of 52 recent CVA16 strains demonstrated two distinct CVA16 genogroups, A and B, with the prototype strain being the only member of genogroup A. CVA16 G-10, the prototype strain, showed a nucleotide difference of 27.7–30.2% and 19.9–25...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer-Verlag
2007
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| Subjects: | |
| Online Access: | http://ir.unimas.my/id/eprint/13623/ http://ir.unimas.my/id/eprint/13623/1/Molecular%20phylogeny%20of%20modern%20coxsackievirus%20A16%20%28abstract%29.pdf |
| Summary: | A phylogenetic analysis of VP1 and VP4 nucleotide
sequences of 52 recent CVA16 strains demonstrated
two distinct CVA16 genogroups, A and B,
with the prototype strain being the only member
of genogroup A. CVA16 G-10, the prototype strain,
showed a nucleotide difference of 27.7–30.2% and
19.9–25.2% in VP1 and VP4, respectively, in relation
to other CVA16 strains, which formed two
separate lineages in genogroup B with nucleotide
variation of less than 13.4% and less than 16.3%
in VP1 and VP4, respectively. Lineage 1 strains
circulating before 2000 were later displaced by lineage
2 strains. |
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